Results 91 to 100 of about 707,817 (385)

Effect of counterface on cartilage boundary lubricating ability by proteoglycan 4 and hyaluronan: Cartilage‐glass versus cartilage–cartilage [PDF]

Journal of Orthopaedic Research, 2018
ABSTRACTThe objective of this study was to determine the effect of different sliding interface materials (counterface) on the cartilage lubricating ability of proteoglycan 4 (PRG4) and hyaluronan (HA) by measuring the kinetic coefficient of friction on cartilage‐glass and cartilage–cartilage interfaces over a wide range of sliding velocities.
Philip Egberts, Saleem Abubacker, Sam G. Dorosz, Tannin A. Schmidt, Allison McPeak   +4 more
openaire   +3 more sources

Diffusion‐Weighted Imaging for the Evaluation of the Sacroiliac Joint in Pediatric Patients

Arthritis Care &Research, Accepted Article.
Background Maturational signal in the sacroiliac joint (SIJ) of skeletally immature youth is often misinterpreted as inflammation. Diagnostic tools that improve specificity are greatly needed. Apparent diffusion coefficient (ADC) values from diffusion‐weighted imaging (DWI), when used with standard imaging, may enhance diagnostic accuracy.
Michael L. Francavilla, Timothy G. Brandon, Dmitry Khrichenko, Rui Xiao, Nancy A. Chauvin, Asef Khwaja, Pamela F. Weiss   +6 more
wiley   +1 more source

Increased oxidative phosphorylation through pyruvate dehydrogenase kinase 2 deficiency ameliorates cartilage degradation in mice with surgically induced osteoarthritis

Experimental and Molecular Medicine
Chondrocytes can shift their metabolism to oxidative phosphorylation (OxPhos) in the early stages of osteoarthritis (OA), but as the disease progresses, this metabolic adaptation becomes limited and eventually fails, leading to mitochondrial dysfunction ...
Jin Han, Yoon Hee Kim, Seungwoo Han
doaj   +1 more source

Antimicrobial potency, prevention ability, and killing efficacy of daptomycin-loaded versus vancomycin-loaded β-tricalcium phosphate/calcium sulfate for methicillin-resistant Staphylococcus aureus biofilms

Frontiers in Microbiology, 2022
Growing evidence has shown that the efficacy of systemic administration of daptomycin for the treatment of methicillin-resistant Staphylococcus aureus (MRSA)-related infections is satisfactory.
Xin Zhang, Xin Zhang, Peng Chen, Peng Chen, Hao-yang Wan, Run-jiu Zhu, Yue Zhou, Ming-rui Song, Nan Jiang, Nan Jiang, Bin Yu, Bin Yu   +11 more
doaj   +1 more source

Growth factor releasing scaffolds for cartilage tissue engineering [PDF]

, 2006
Over the last century, life expectancy has increased at a rapid pace resulting in an increase of articular cartilage disorders. To solve this problem, extensive research is currently performed using tissue engineering approaches.
Sohier, Jerome
core   +2 more sources

Viscoelastic properties of human and bovine articular cartilage : a comparison of frequency-dependent trends [PDF]

, 2016
Acknowledgments The authors would like to thank Spencer C. Barnes and Hamid Sadeghi for assistance during experimentation. We would also like to thank patients donating tissue and the surgeons collecting these.
Aspden, Richard M., Aspden, Richard M., Cederlund, Anna A., Espino, Daniel M., Lawless, Bernard M., Temple, Duncan K.   +5 more
core   +3 more sources

Mesenchymal Stromal/stem Cell-derived Extracellular Vesicles Promote Human Cartilage Regeneration In Vitro

Theranostics, 2018
Osteoarthritis (OA) is a rheumatic disease leading to chronic pain and disability with no effective treatment available. Recently, allogeneic human mesenchymal stromal/stem cells (MSC) entered clinical trials as a novel therapy for OA.
L. Vonk, S. van Dooremalen, N. Liv, J. Klumperman, P. Coffer, D. Saris, M. Lorenowicz   +6 more
semanticscholar   +1 more source

Autologous Minced Cartilage Implantation for Treatment of Chondral and Osteochondral Lesions in the Knee Joint: An Overview

Cartilage, 2020
Cartilage defects in the knee are being diagnosed with increased frequency and are treated with a variety of techniques. The aim of any cartilage repair procedure is to generate the highest tissue quality, which might correlate with improved clinical ...
G. Salzmann, R. Ossendorff, Ron Gilat, B. Cole   +3 more
semanticscholar   +1 more source

Retrotransposon Expression Is Upregulated in Adulthood and Suppressed during Regeneration of the Limb in the Axolotl (Ambystoma mexicanum)

Advanced Biology, EarlyView.
The axolotl's remarkable regenerative abilities decline with age, the causes may include the numerous repetitive elements within its genome. This study uncovers how Ty3 retrotransposons and coexpression networks involving muscle and immune pathways respond to aging and regeneration, suggesting that transposons respond to physiological shifts and may ...
Samuel Ruiz‐Pérez, Nicolás Alcaraz, Karla Torres‐Arciga, José Antonio Ocampo‐Cervantes, Alejandra Cervera, Clementina Castro‐Hernández, Cynthia Gabriela Sámano‐Salazar, Ernesto Soto‐Reyes, Rodrigo González‐Barrios   +8 more
wiley   +1 more source

Use of autologous adipose-derived mesenchymal stem cells for creation of laryngeal cartilage [PDF]

, 2017
OBJECTIVES/HYPOTHESIS: Adipose-derived mesenchymal stem cells (ASCs) are an exciting potential cell source for tissue engineering because cells can be derived from the simple excision of autologous fat.
Brookes, Sarah, Halum, Stacey, Parker, Noah, Voytik-Harbin, Sherry, Wallace, Joseph, Zhang, Hongji, Zhang, Lujuan   +6 more
core   +1 more source