Results 91 to 100 of about 215,224 (198)

Targeting CCNB1 Repressed Cartilage Degradation Induced by Inflammation Through NF-κB Pathway in Osteoarthritis. [PDF]

J Histochem Cytochem
Li H, Qiao Y, Ding M, Liu Y.
europepmc   +1 more source

Development‐based In Vivo Bioreactor Strategy for Challenging Senescent Bone Reconstruction

Advanced Science, EarlyView.
We present a development‐based in vivo bioreactor strategy to generate rejuvenated bone grafts (vBR‐Bone) within aged hosts. By enclosing vBR‐Bone fragments within an asymmetric biomimetic periosteum, segmental femoral defects in aged mice were successfully repaired within 6 weeks. Mechanistically, the multifactors of vBR‐Bone reconstitute a remodeling
Wenchao Zhang, Kai Dai, Tong Shen, Zehua Gao, Fengying Yan, Yuke Feng, Xuanlin Wang, Shaozhen Zhang, Jing Wang, Changsheng Liu   +9 more
wiley   +1 more source

Ultrasoft Yet Tough Multifunctional Organohydrogels Enabled by Molecular Chain Lubrication Strategy for Self‐Powered Wearable Electronics

Advanced Science, EarlyView.
An ultrasoft yet tough organohydrogel (AQGL) with 5800% stretchability and 14.3 kPa modulus is developed via a novel molecular chain lubrication strategy. It features optical transparency, drying/freezing (−40°C) tolerance, antibacterial activity, conductivity, self‐healing, and adhesiveness.
Si Wang, Lin Hu, Mingbo Pu, Mingfeng Xu, Tao Zhou, Hanbing Rao, Xiong Li, Xiaoliang Ma, Gehong Su, Xiangang Luo   +9 more
wiley   +1 more source

Age-dependent development and microarchitecture of the osteochondral unit of the humeral head in harbour porpoises (Phocoena phocoena). [PDF]

Sci Rep
Księżarczyk MM, IJsseldijk LL, van Weeren PR, Levato R, Malda J.   +4 more
europepmc   +1 more source

Beyond Cartilage‐Inspired Supramolecular Polyurethane for Adaptive Impact‐Resistant Protection with Robustness, Self‐Healing, and Recyclability

Advanced Science, EarlyView.
Cartilage‐inspired supramolecular polyurethane–urea (PU‐BAMB) elastomers are developed by integrating hierarchical hydrogen bonding and π–π stacking interactions within a dynamically reconfigurable network. This synergistic supramolecular architecture overcomes the intrinsic trade‐off between rigidity and recoverability, imparting exceptional toughness,
Rou‐Han Lai, Chia‐An Chiu, Yi‐An Chen, Athis Watwiangkham, Yu‐Hung Cheng, Yan‐Heng Chen, Min‐Han Yu, Lung‐Yi Lu, Chun‐Hsien Chen, Yi‐Ting Chen, Wei‐Hsiang Liao, Shang‐Hsiu Hu, Hsin‐Lung Chen, Siriporn Jungsuttiwong, Ho‐Hsiu Chou   +14 more
wiley   +1 more source

Biophysical signal-driven scaffold design for stem cell-guided osteochondral regeneration. [PDF]

Bioact Mater
Gao Y, Zhuang Y, Zhu T, Zhang H, Wang Y, Chang F, Ding J.   +6 more
europepmc   +1 more source

Harnessing Phase Separation for the Development of High‐Performance Hydrogels

Advanced Science, EarlyView.
ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao, Yiming Ma, Baihao Shao, Molly M. Stevens   +3 more
wiley   +1 more source

A dual-functional hydrogel integrating adhesive and lubricating interfaces for mitochondrial protection-Driven cartilage regeneration. [PDF]

Bioact Mater
Wu Z, Wu G, Zhu Y, Zheng G, Wang T, Liu J, Shen Z, Wang X, Bei X, Xu Y, Li J, Yuan R, Wu Z, Guo Y, Zhang Y, Peng F.   +15 more
europepmc   +1 more source

Artificial Piezoelectric Interface Enables Ultrafast Interfacial Ion Kinetic for Highly‐Sensitive Piezoionic Sensors

Advanced Science, EarlyView.
This study proposes a piezoelectric interface modification strategy to amplify the piezoionic effect. The piezoelectric interface generates an intrinsic electric field, which not only drives rapid ion migration but also concentrates polarized ions on the interface. The flexible sensor delivers superior performance, such as a quick response rate, strong
Yanyu Chen, Xingyue Ling, Rizhong Gao, Xiaohong Zhang, Xi Chen, Chao Lu   +5 more
wiley   +1 more source

Critical Size Defect in Adult Articular Cartilage: A Preclinical Study. [PDF]

Cartilage
Hunziker EB, Shintani N, Keel MJB.
europepmc   +1 more source