Ultra‐Fine 3D Bioprinting of Dynamic Hyaluronic Acid Hydrogel for in Vitro Modeling
3D bioprinting merges tissue engineering and additive manufacturing to create biological structures. A bioink is developed by modifying hyaluronic acid, a natural extracellular matrix polymer, with cysteine. Potassium iodide is later added to tune gelation kinetics, enabling fine printing with a 32G needle.
Shima Tavakoli+3 more
wiley +1 more source
A closed-form solution of the three-dimensional contact problem for biphasic cartilage layers [PDF]
A three-dimensional unilateral contact problem for articular cartilage layers is considered in the framework of the biphasic cartilage model. The articular cartilages bonded to subchondral bones are modeled as biphasic materials consisting of a solid phase and a fluid phase.
arxiv
Bioxolography, a novel volumetric 3D‐bioprinting technique, enables rapid and high‐resolution fabrication of >1 cm3 engineered living materials. A newly developed three‐component photoinitiator system significantly enhances the photoreactivity of gelatin methacryloyl‐based bioresins, allowing for precise xolographic bioprinting.
Alexis Wolfel+6 more
wiley +1 more source
Shear loading of costal cartilage [PDF]
A series of tests were performed on a single post-mortem human subject at various length scales. First, tabletop tests were performed. Next, the ribs and intercostal muscles were tested with the view to characterize the load transfer between the ribs. Finally, the costal cartilage was tested under shear loading, as it plays an important in the transfer
arxiv
Preliminary characterisation of the surface of cartilage following exposure to saturated and unsaturated synthetic lips [PDF]
Articular cartilage is covered by a microscopic structure known as surface amorphous layer. This surface structure is often the first victim of attack during cartilage degeneration, thereby resulting in a gross impairment in cartilage function such as ...
Gudimetla, Prasad+3 more
core +2 more sources
Adjusting Cell‐Surface Interactions Through a Covalent Immobilization of Biomolecules
This review presents an overview of current and emerging immobilization techniques coupled with an in‐depth investigation of the underlying mechanisms governing the activity and stability of covalently immobilized biomolecules. The aim of this study is to serve as a guide for the development of long‐lasting biomedical coatings with versatile biological
Sara Shakibania+2 more
wiley +1 more source
Introduction: Chondroplasty is a surgical option for chondral defects, but its effect on larger cartilage defects in the setting of knee osteoarthritis remains unclear.
Yusuf Mufti+6 more
doaj
Large animal models in experimental knee sports surgery: focus on clinical translation
Large animal models play a crucial role in sports surgery of the knee, as they are critical for the exploration of new experimental strategies and the clinical translation of novel techniques.
Henning Madry+4 more
doaj +1 more source
Collaborative Multi-agent Learning for MR Knee Articular Cartilage Segmentation [PDF]
The 3D morphology and quantitative assessment of knee articular cartilages (i.e., femoral, tibial, and patellar cartilage) in magnetic resonance (MR) imaging is of great importance for knee radiographic osteoarthritis (OA) diagnostic decision making. However, effective and efficient delineation of all the knee articular cartilages in large-sized and ...
arxiv
T1ρ-based fibril-reinforced poroviscoelastic constitutive relation of human articular cartilage using inverse finite element technology [PDF]
BackgroundMapping of T1ρ relaxation time is a quantitative magnetic resonance (MR) method and is frequently used for analyzing microstructural and compositional changes in cartilage tissues.
Alliston, Tamara+6 more
core +1 more source