Comparison of Knee Articular Cartilage Defect Size Between Measurements Obtained on Preoperative MRI Versus During Arthrotomy [PDF]
Orthopaedic Journal of Sports Medicine, 2023 Background: Treatment decisions for cartilage defects are often based on lesion size. Magnetic resonance imaging (MRI) is widely used to diagnose cartilage defects noninvasively; however, their size estimated from MRI may differ from defect sizes ...
Jade Perry PhD +6 more
doaj +2 more sources
Knee focal cartilage defect location heat map and local surface morphology characterisation: Insights for focal knee resurfacing implant design [PDF]
Journal of Experimental OrthopaedicsPurpose The objective of this work was to characterise the dimensions of knee focal cartilage defects, generate a heat map of cartilage defect locations, and characterise the native articular surface morphology at the most common defect sites to aid in ...
Majid Mohammad Sadeghi +6 more
doaj +2 more sources
Construction of 3D-Bioprinted cartilage-mimicking substitute based on photo-crosslinkable Wharton's jelly bioinks for full-thickness articular cartilage defect repair [PDF]
Materials Today Bio, 2023 Three-dimensional (3D) bioprinted cartilage-mimicking substitutes for full-thickness articular cartilage defect repair have emerged as alternatives to in situ defect repair models.
Guanhuai Hu +11 more
doaj +2 more sources
Three-dimensional MRI shows cartilage defect extension with no separation from the meniscus in women in their 70 s with knee osteoarthritis [PDF]
Scientific Reports, 2022 The positional relationship between cartilage defects and the meniscus is poorly understood for osteoarthritis of the knee. Our purpose was to clarify how cartilage defects extend and their association with the meniscus location during osteoarthritis ...
Hisako Katano +6 more
doaj +2 more sources
Senescence-targeted MicroRNA/Organoid composite hydrogel repair cartilage defect and prevention joint degeneration via improved chondrocyte homeostasis [PDF]
Bioactive MaterialsIntroduction: Cartilage defect (CD) is a common complication in osteoarthritis (OA). Impairment of chondrogenesis and cellular senescence are considered as hallmarks of OA development and caused failure of cartilage repair in most clinical CD cases ...
Ye Sun +4 more
doaj +2 more sources
MRI monitoring of USPIO-labeled BMSCs combined with alginate scaffold for cartilage defect repair [PDF]
Frontiers in Bioengineering and BiotechnologyObjectiveThis study aimed to evaluate the effectiveness of bone marrow mesenchymal stem cells (BMSCs) combined with sodium alginate scaffolds in repairing knee cartilage defects in New Zealand rabbits.
Shanyu Lu +19 more
doaj +2 more sources
Hyaluronic acid hydrogel encapsulated BMP-14-modified ADSCs accelerate cartilage defect repair in rabbits [PDF]
Journal of Orthopaedic Surgery and Research, 2021 Background Cartilage defect has a limited capacity to heal. In this context, we hypothesized that hyaluronic acid (HA) hydrogel encapsulated BMP-14-modified adipose-derived mesenchymal stem cells (ADSCs) could accelerate cartilage defect repair in ...
Hao Liu +4 more
doaj +2 more sources
Advances in the Treatment of Partial-Thickness Cartilage Defect [PDF]
International Journal of Nanomedicine, 2022 Xu Liangliang
exaly +2 more sources
Time Matters: Knee Cartilage Defect Expansion and High-Grade Lesion Formation while Awaiting Autologous Chondrocyte Implantation [PDF]
Cartilage, 2021 Robert Pettit +2 more
exaly +2 more sources
Intra-articular Administration of Triamcinolone Acetonide in a Murine Cartilage Defect Model Reduces Inflammation but Inhibits Endogenous Cartilage Repair [PDF]
American Journal of Sports Medicine, 2022 Laura Creemers +2 more
exaly +2 more sources