Results 191 to 200 of about 108,199 (280)

SGK1 triggers cartilage degradation in TMJOA via FoxO1/autophagy. [PDF]

Arthritis Res Ther
Tang H, Ma C, Xu M, Wu G, Li N, Chen L.
europepmc   +1 more source

circNR3C2 promotes chondrogenic differentiation and cartilage repair of human adipose‐derived stem cells via the hsa‐miR‐647/SOX9 pathway

Animal Models and Experimental Medicine, EarlyView.
The hypothesis diagram illustrates the function and mechanism of circNR3C2: circNR3C2 overexpression can up‐regulate COL2, Aggrecan and SOX9 expression, and regulate chondrogenic differentiation of hADSCs by targeting hsa‐miR‐647. Abstract Background Human adipose‐derived stem cells (hADSCs) are seed cells with application prospects in cartilage repair.
Dabiao Hou, Huajun Wang, Hao Guo, Dongbin Luo, Xiaofei Zheng, Simin Luo   +5 more
wiley   +1 more source

Emerging concepts in osteoarthritis and musculoskeletal diseases: Insights from the University of Debrecen Musculoskeletal Symposium 2025. [PDF]

Osteoarthr Cartil Open
Kovács P, Vágó J, Mobasheri A, Jenei-Lanzl Z, Zaucke F, Madry H, Csernoch L, Szekanecz Z, Szondy Z, Szöőr Á, Szatmari I, Oláh T, Matta C.   +12 more
europepmc   +1 more source

Time‐ and dose‐related pathological changes in knee osteoarthritis rat model induced by monosodium iodoacetate

Animal Models and Experimental Medicine, EarlyView.
Time‐ and dose‐related pathological changes of knee osteoarthritis rat model induced by monosodium iodoacetate. Abstract Knee osteoarthritis (KOA) is a chronic degenerative disease. Monosodium iodoacetate (MIA) induction is the most commonly used therapeutic effect evaluation and mechanism of action research model; we observed a lack of standardization
Wei Pu, Qi Liu, Shuyan Xue, Siyuan Li, Nan Nan, Yang Liu, Huiqin Hao   +6 more
wiley   +1 more source

Nell-1 regulates fibrocartilage stem cells and alleviates temporomandibular joint osteoarthritis progression by inhibiting hedgehog pathway. [PDF]

J Orthop Surg Res
Hu S, Wu N, Wang C, Li W, Shi J.
europepmc   +1 more source

Animal models of benign airway stenosis: Advances in construction techniques, evaluation systems, and perspectives

Animal Models and Experimental Medicine, EarlyView.
Currently, the animals commonly used to establish animal models of benign airway stenosis (BAS) include mice, rats, pigs, dogs, rabbits, and ferrets. The establishment methods involve one or a combination of two methods such as mechanical injury, tracheal cautery, cuff overpressure intubation, laser injury, and endoscopic silver nitrate cauterization ...
Wusheng Zhang, Yilin Chen, Chengcheng Yang, Yuchao Dong, Haidong Huang, Hui Shi, Chong Bai   +6 more
wiley   +1 more source

Oral administration of soybean okara extract reduces osteoarthritis pain and progression in rats. [PDF]

Int J Med Sci
Lee KT, Chen CM, Tang CH, Lin YY, Chang TC, Wu MH, Chang SL.   +6 more
europepmc   +1 more source

Cartilage pathology in MPS VI: disease modeling using iPSCs and CRISPR/Cas9

, 2021
Mike Broeders
openalex   +1 more source

3D Hydrogel Cell Cultures and Their Biomedical Applications

Advanced NanoBiomed Research, EarlyView.
The review highlights the advantages of hydrogel‐based 3D cell cultures over traditional 2D models. These hydrogels closely mimic natural cellular environments, improving research in tissue engineering, drug discovery, cancer studies, and neuroscience.
Tri Lan Thai, Arushi Manchanda, Sarah L. Higginbottom, Estrella Sanz Rodriguez, Richard Wilson, Eva Tomaskovic‐Crook, Jeremy M. Crook, Brett Paull   +7 more
wiley   +1 more source

Targeting mitochondrial oxidative stress: A novel therapeutic strategy for degenerative joint diseases (Review). [PDF]

Biomed Rep
Hou Y, Yang X, Zhao T, Guo Y, Shi J.
europepmc   +1 more source