Prevalence of knee radiographic and symptomatic osteoarthritis and ultrasound features across sex and body mass index groups: The Johnston County Health Study. [PDF]
Patel M +12 more
europepmc +1 more source
MDL‐800‐induced SIRT6 activation decreases age‐associated osteoarthritis in mice
Objective SIRT6 is a nuclear‐localized histone deacetylase that regulates multiple pathways associated with aging. This study aimed to determine whether systemic administration of a small molecule activator of SIRT6, MDL‐800, decreases the severity of age‐associated osteoarthritis (OA) in mice.
Matheus Moreira Perez +13 more
wiley +1 more source
Quantifying knee cartilage development trajectories in children aged 6-12 years via diffusion tensor imaging. [PDF]
Cheng Z +9 more
europepmc +1 more source
Objective Calcium pyrophosphate deposition (CPPD) disease is a heterogeneous condition and is frequently misdiagnosed due to the different clinical presentations and variable disease progression. Aim of this study is to identify clinical phenotypes of CPPD disease by integrating real‐world data from two data sets. Methods Data from the COLCHICORT trial
Greta Pellegrino +20 more
wiley +1 more source
Effects of anti-aging diets and exercise on age-related musculoskeletal diseases via gut microbiota modulation. [PDF]
Yu M, Guo P, Liu Q, Zhang XA.
europepmc +1 more source
Abstract The anterior cruciate ligament (ACL) and anterolateral ligament (ALL) play key roles in maintaining rotational stability of the knee joint. Injuries that cause ACL tears have been shown to also frequently compromise the integrity of the ALL.
Taidhgin J. Keel +6 more
wiley +1 more source
Correction: Mechanotransduction in intervertebral disc degeneration: from compartment-specific sensors to translational frontiers. [PDF]
Li H +8 more
europepmc +1 more source
Abstract Bone block transfer for the treatment of glenohumeral instability with severe glenoid bone loss or multiple recurrences has grown in popularity in recent years. In this technical note, we described an arthroscopic‐assisted free bone block transfer technique, using a specially designed anchor‐button unit to treat glenohumeral instability caused
Batuhan Bahadir +6 more
wiley +1 more source
Exploring the therapeutic applications of metformin in articular cartilage repair: mechanistic insights and translational perspectives. [PDF]
Jin P +11 more
europepmc +1 more source
Abstract Subchondral insufficiency fracture of the knee, previously known as spontaneous osteonecrosis of the knee, commonly affects the medial femoral condyle and may progress to subchondral collapse and eventually osteoarthritis. Joint‐preserving options for focal medial femoral condyle lesions remain limited, particularly in middle‐aged patients ...
Eugene Pak‐Lin Ng +5 more
wiley +1 more source

