Results 191 to 200 of about 192,550 (253)

Autoantibodies to Joint‐Related Peptides Are Associated with Onset of Rheumatoid Arthritis in Presymptomatic Seronegative Individuals

Arthritis &Rheumatology, Accepted Article.
Objective To identify autoantibodies in presymptomatic individuals that associate with the onset of rheumatoid arthritis (RA), and to distinguish early RA from osteoarthritis (OA), particularly in individuals lacking classic RA serological markers. Methods We analyzed serum and plasma from three cohorts: pre‐symptomatic individuals who later developed ...
Outi Sareila, Linda Johansson, Anders Lundquist, Monica Leu Agelii, Lei Cheng, Yibo He, Erik Lönnblom, Maria Andersson, Jan Kihlberg, Anders Esberg, Inger Gjertsson, Rikard Holmdahl, Solbritt Rantapää‐Dahlqvist   +12 more
wiley   +1 more source

A Systematic Review on Amnion as a Cell Delivery Scaffolding Material for Cartilage Regeneration in Pre-Clinical and Clinical Studies. [PDF]

Bioengineering (Basel)
Liow SY, Tan SL, Lu AJ, Loh KW, Teo SH, Lee CY, Wan L, Abbas AA, Park KS.   +8 more
europepmc   +1 more source

autoscoRA: Deep Learning to Automate Sharp/van der Heijde Scoring of Radiographic Damage in Rheumatoid Arthritis

Arthritis &Rheumatology, Accepted Article.
Objective Regular imaging by conventional radiography to assess for joint damage is a cornerstone in the management of rheumatoid arthritis (RA). Scoring systems to quantify such damage, such as the widely used Sharp/van der Heijde (SvdH) score, are limited by the requirement of time and experienced staff as well as intra‐ and inter‐rater variability ...
Thomas Deimel, Paul J. Weiser, Martin Urschler, Christian Payer, Peter Mandl, Georg Langs, Daniel Aletaha   +6 more
wiley   +1 more source

Hemochromatosis osteoarthritis. [PDF]

Front Endocrinol (Lausanne)
Yang Y, Zu Z, Huang Y.
europepmc   +1 more source

T cells, the next big target in axSpA?

Arthritis &Rheumatology, Accepted Article.
Axial spondyloarthritis (axSpA) is a chronic inflammatory disease characterized by complex immune dysregulation, with T cells playing a central role in its pathogenesis. In this review we synthesize current knowledge on diverse T cell subsets in axSpA, their pathogenic mechanisms, and emerging therapeutic strategies targeting these cells.
Mansi K. Aparnathi, Nigil Haroon
wiley   +1 more source

Long-Term Efficacy of Arthroscopic Microfracture Combined With Autologous Collagen-Induced Chondrogenesis for Knee Cartilage Defects: A 5-Year Prospective Pilot Randomized Controlled Trial. [PDF]

Orthop Surg
Ren S, Bai Z, Lu X, Zhang Y, Sun X, Tang R, Yang B, Qian J, Qiu G.   +8 more
europepmc   +1 more source

Endoscopic Resection of Bizarre Parosteal Osteochondromatous Proliferation of the Calcaneocuboid Joint

Arthroscopy Techniques, EarlyView.
Abstract Bizarre parosteal osteochondromatous proliferation (BPOP), or Nora's lesion, is an unusual, benign, parosteal lesion comprising bone, fibrous tissue, and cartilage. Clinically, the lesions present as slowly growing hard protuberances that are painless in most cases unless they cause local symptoms due to mass effect, including pain, palpable ...
Tun Hing Lui, Kit Leung
wiley   +1 more source

Articular cartilage thickness alterations in hind limb of young and aged PAC1 gene-deficient mice. [PDF]

Cell Tissue Res
Fillér C, Kovács LS, Rácz K, Segal Y, Vágó J, Tóth A, Szegeczki V, Jüngling A, Gergely P, Zákány R, Reglődi D, Juhász T.   +11 more
europepmc   +1 more source

Advanced therapy medicinal products (ATMPs) – An analysis of the global regulatory status

British Journal of Clinical Pharmacology, EarlyView.
Abstract Background A rapid progress in the development of advanced therapy medicinal products (ATMPs) has taken place over the past decades. The ATMPs hold great potential but face challenges in the clinical development and the regulatory process.
Allan Cramer, Freja Karuna Hemmingsen Sørup, Marie Lund, Tonny Studsgaard Petersen, Kristian Karstoft   +4 more
wiley   +1 more source

The role of neutrophils in the pathophysiology of knee osteoarthritis : a review. [PDF]

Bone Joint Res
Štefančík M, Goodman SB, Gallo J.
europepmc   +1 more source