Results 11 to 20 of about 96,982 (307)

Comparative study of alginate and type I collagen as biomaterials for cartilage stem/progenitor cells to construct tissue-engineered cartilage in vivo

Frontiers in Bioengineering and Biotechnology, 2023
With the help of biomaterials, cartilage stem/progenitor cells (CSPCs) derived from cartilage tissue present a promising choice for cartilage regeneration.
Xiaodie Zhang, Lin Qi, XiaoGang Chen, Yongxian Lai, Kai Liu, Ke Xue, Ke Xue   +6 more
doaj   +1 more source

Laryngeal Cartilage Regeneration of Nude Rats by Transplantation of Mesenchymal Stem Cells Derived from Human-Induced Pluripotent Stem Cells

Cell Transplantation, 2023
Previous studies transplanted human-induced pluripotent stem cells (hiPSCs)-derived mesenchymal stem cells (iMSCs) into thyroid cartilage defect of X-liked severe combined immunodeficiency (X-SCID) rats and confirmed transplanted cell survival and ...
Keisuke Mizuno, Hiroe Ohnishi, Masayoshi Yoshimatsu, Chengzhu Zhao, Yasuyuki Hayashi, Fumihiko Kuwata, Shinji Kaba, Hideaki Okuyama, Yoshitaka Kawai, Nao Hiwatashi, Yo Kishimoto, Tatsunori Sakamoto, Makoto Ikeya, Koichi Omori   +13 more
doaj   +1 more source

Hypotrochoidal scaffolds for cartilage regeneration

Materials Today Bio, 2022
AbstractThe main function of articular cartilage is to provide a low friction surface and protect the underlying subchondral bone. The extracellular matrix composition of articular cartilage mainly consists of glycosaminoglycans and collagen type II.
Kenny A. van Kampen, Elena Olaret, Izabela-Cristina Stancu, Daniela F. Duarte Campos, Horst Fischer, Carlos Mota, Lorenzo Moroni   +6 more
openaire   +4 more sources

Defactinib attenuates osteoarthritis by inhibiting positive feedback loop between H-type vessels and MSCs in subchondral bone

Journal of Orthopaedic Translation, 2020
Summary: Background: Abnormal bone formation in subchondral bone resulting from uncoupled bone remodeling is considered a central feature in osteoarthritis (OA) pathogenesis. H-type vessels can couple angiogenesis and osteogenesis.
Yanjun Hu, Hangtian Wu, Ting Xu, Yutian Wang, Hanjun Qin, Zilong Yao, Peisheng Chen, Yongheng Xie, Zhiguo Ji, Kaifan Yang, Yu Chai, Xianrong Zhang, Bin Yu, Zhuang Cui   +13 more
doaj   +1 more source

Polymer- and Hybrid-Based Biomaterials for Interstitial, Connective, Vascular, Nerve, Visceral and Musculoskeletal Tissue Engineering [PDF]

, 2020
In this review, materials based on polymers and hybrids possessing both organic and inorganic contents for repairing or facilitating cell growth in tissue engineering are discussed.
Abalymov, Anatolii, Parakhonskiy, Bogdan, Skirtach, Andre   +2 more
core   +1 more source

Injectable hydrogel microspheres in cartilage repair

Biomedical Technology, 2023
The key to regenerative medicine is in situ regeneration of lesion cells, so as to achieve lesion repair and regeneration. However, the complex environment of the joint cavity where cartilage is located leads to poor efficacy of traditional therapies to ...
Feng Lin, Yihan Li, Wenguo Cui
doaj   +1 more source

Construction of three-dimensional, homogeneous regenerative cartilage tissue based on the ECG-DBM complex

Frontiers in Bioengineering and Biotechnology, 2023
Introduction: The feasibility of using a steel decalcified bone matrix (DBM)-reinforced concrete engineered cartilage gel (ECG) model concept for in vivo cartilage regeneration has been demonstrated in preliminary experiments.
Jingwen Liu, Jingwen Liu, Jingwen Liu, Feifan Chen, Feifan Chen, Daiying Song, Daiying Song, Qixin Zhang, Peizhe Li, Peizhe Li, Zheng Ci, Wei Zhang, Wei Zhang, Guangdong Zhou, Guangdong Zhou   +14 more
doaj   +1 more source

Human stem cells and articular cartilage regeneration. [PDF]

, 2012
The regeneration of articular cartilage damaged due to trauma and posttraumatic osteoarthritis is an unmet medical need. Current approaches to regeneration and tissue engineering of articular cartilage include the use of chondrocytes, stem cells ...
Inui, Atsuyuki, Iwakura, Takashi, Reddi, A Hari   +2 more
core   +4 more sources

Achieving Nasal Septal Cartilage In Situ Regeneration: Focus on Cartilage Progenitor Cells

Biomolecules, 2023
The nasal septal cartilage plays an important role in preventing the collapse of the nasal bones and maintaining the appearance of the nose. In the context of inherent difficulties regarding septal cartilage repair and the shortage of cartilage graft ...
Chong Zhang, Guanhuier Wang, Yang An
doaj   +1 more source

Optimal conditions of collagenase treatment for isolation of articular chondrocytes from aged human tissues

Regenerative Therapy, 2017
Introduction: There are various types of cartilage, including the auricular and articular cartilages. These cartilages have different functions, and their matrix volume and density of chondrocytes may differ.
Kazumichi Yonenaga, Satoru Nishizawa, Takumi Nakagawa, Yuko Fujihara, Yukiyo Asawa, Atsuhiko Hikita, Tsuyoshi Takato, Kazuto Hoshi   +7 more
doaj   +1 more source