Results 21 to 30 of about 96,982 (307)
PRP and BMAC for Musculoskeletal Conditions via Biomaterial Carriers. [PDF]
, 2019 Platelet-rich plasma (PRP) and bone marrow aspirate concentrate (BMAC) are orthobiologic therapies considered as an alternative to the current therapies for muscle, bone and cartilage. Different formulations of biomaterials have been used as carriers for
Shams, Shahin +3 more
core +1 more source
Magnetically Controlled 3D Cartilage Regeneration
CARTILAGE, 2023 Objective The cartilage regeneration field has not yet overcome the issue of effective “shaping”: growing regenerated cartilage in the desired shape, and maintaining that shape, is problematic. This study reports on a new method of cartilage regeneration in which the cartilage is shaped in three dimensions. Since cartilage is composed only of cartilage
Xia Chen +6 more
openaire +2 more sources
Endogenous musculoskeletal tissue engineering - a focused perspective [PDF]
, 2012 Two major difficulties facing widespread clinical implementation of existing Tissue Engineering (TE) strategies for the treatment of musculoskeletal disorders are (1) the cost, space and time required for ex vivo culture of a patient’s autologous cells ...
Adam, Clayton
core +2 more sources
Military Medical Research, 2022 Bone, cartilage, and soft tissue regeneration is a complex spatiotemporal process recruiting a variety of cell types, whose activity and interplay must be precisely mediated for effective healing post-injury.
Yuan Xiong +13 more
doaj +1 more source
Platelet autologous growth factors decrease the osteochondral regeneration capability of a collagen-hydroxyapatite scaffold in a sheep model [PDF]
, 2010 Current research aims to develop innovative approaches to improve chondral and osteochondral regeneration. The objective of this study was to investigate the regenerative potential of platelet-rich plasma (PRP) to enhance the repair process of a collagen-
Kon, Elizaveta +7 more
core +1 more source
Scientific Reports, 2017 Cartilage tissue is avascular and hypoxic which regulates chondrocyte phenotype via stabilization of HIFs. Here, we investigated the role of hypoxia and HIFs in regulation of Rho and canonical Wnt signaling in chondrocytes.
Ece Öztürk +4 more
doaj +1 more source
Frontiers in Bioengineering and Biotechnology, 2021 The scarcity of ideal biocompatible scaffolds makes the regeneration of cartilage in the subcutaneous environment of large animals difficult. We have previously reported the successful regeneration of good-quality cartilage in a nude mouse model using ...
Rui Zheng +19 more
doaj +1 more source
Articular Cartilage Regeneration in Osteoarthritis [PDF]
Cells, 2019 There has been considerable advancement over the last few years in the treatment of osteoarthritis, common chronic disease and a major cause of disability in older adults. In this pathology, the entire joint is involved and the regeneration of articular cartilage still remains one of the main challenges, particularly in an actively inflammatory ...
Livia Roseti +4 more
openaire +3 more sources
Cell Transplantation, 2012 To overcome the weak points of the present cartilage regenerative medicine, we applied a porous scaffold for the production of tissue-engineered cartilage with a greater firmness and a 3D structure.
Yukiyo Asawa +7 more
doaj +1 more source
Bioactive Materials, 2022 The development of interdisciplinary biomedical engineering brings significant breakthroughs to the field of cartilage regeneration. However, cartilage defects are considerably more complicated in clinical conditions, especially when injuries occur at ...
Zhonghan Wang +8 more
doaj +1 more source