Results 31 to 40 of about 96,982 (307)
Hybrid bioprinting of chondrogenically induced human mesenchymal stem cell spheroids [PDF]
, 2020 To date, the treatment of articular cartilage lesions remains challenging. A promising strategy for the development of new regenerative therapies is hybrid bioprinting, combining the principles of developmental biology, biomaterial science, and 3D ...
Asadian, Mahtab +8 more
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Cell Discovery, 2022 Articular cartilage repair and regeneration is an unmet clinical need because of the poor self-regeneration capacity of the tissue. In this study, we found that the expression of prostaglandin E receptor 4 (PTGER4 or EP4) was largely increased in the ...
Yunyun Jin +19 more
doaj +1 more source
Collagen‐Based Hydrogels for Cartilage Regeneration
Orthopaedic Surgery, 2023 Cartilage regeneration remains difficult due to a lack of blood vessels. Degradation of the extracellular matrix (ECM) causes cartilage defects, and the ECM provides the natural environment and nutrition for cartilage regeneration.
Lihui Sun +9 more
doaj +1 more source
Histological Analysis of Failed Cartilage Repair after Marrow Stimulation for the Treatment of Large Cartilage Defect in Medial Compartmental Osteoarthritis of the Knee [PDF]
, 2013 Bone marrow-stimulating techniques such as microfracture and subchondral drilling are valuable treatments for full-thickness cartilage defects. However, marrow stimulation-derived reparative tissues are not histologically well-documented in human ...
Abe, Nobuhiro +5 more
core +1 more source
Recent advances in 3D printing of biomaterials. [PDF]
, 2015 3D Printing promises to produce complex biomedical devices according to computer design using patient-specific anatomical data. Since its initial use as pre-surgical visualization models and tooling molds, 3D Printing has slowly evolved to create one-of ...
Chia, Helena N, Wu, Benjamin M
core +2 more sources
Applied Sciences, 2019 Numerous clinical studies have reported cell-based treatments for cartilage regeneration in knee joint osteoarthritis using mesenchymal stem cells (MSCs). However, the post-surgery rehabilitation and weight-bearing times remain unclear.
Yong-Gon Koh +4 more
doaj +1 more source
Serum and synovial fluid lipidomic profiles predict obesity-associated osteoarthritis, synovitis, and wound repair [PDF]
, 2017 High-fat diet-induced obesity is a major risk factor for osteoarthritis (OA) and diminished wound healing. The objective of this study was to determine the associations among serum and synovial fluid lipid levels with OA, synovitis, adipokine levels, and
Guilak, Farshid +3 more
core +2 more sources
Laser-induced regeneration of cartilage [PDF]
Journal of Biomedical Optics, 2011 Laser radiation provides a means to control the fields of temperature and thermo mechanical stress, mass transfer, and modification of fine structure of the cartilage matrix. The aim of this outlook paper is to review physical and biological aspects of laser-induced regeneration of cartilage and to discuss the possibilities and prospects of its ...
Sobol, E +4 more
openaire +3 more sources
Toward regeneration of articular cartilage [PDF]
Birth Defects Research Part C: Embryo Today: Reviews, 2013 AbstractArticular cartilage is classified as permanent hyaline cartilage and has significant differences in structure, extracelluar matrix components, gene expression profile, and mechanical property from transient hyaline cartilage found in the epiphyseal growth plate.
Masahiro, Iwamoto +3 more
openaire +2 more sources
Arthroscopy combined with high tibial osteotomy promotes cartilage regeneration in osteoarthritis
Journal of Orthopaedic Surgery, 2023 Background To investigate the effect of arthroscopy combined with high tibial osteotomy (HTO) on cartilage regeneration in patients with knee osteoarthritis. Methods A retrospective analysis of 50 patients with varus and medial compartment osteoarthritis
Jiang Wu +7 more
doaj +1 more source