Results 41 to 50 of about 96,982 (307)

Hopes and opportunities of stem cells from human exfoliated deciduous teeth (SHED) in cartilage tissue regeneration

Frontiers in Bioengineering and Biotechnology, 2023
Cartilage lesions are common conditions, affecting elderly and non-athletic populations. Despite recent advances, cartilage regeneration remains a major challenge today.
Forough Mahdavi-Jouibari, Benyamin Parseh, Benyamin Parseh, Ezatolah Kazeminejad, Ezatolah Kazeminejad, Ayyoob Khosravi, Ayyoob Khosravi   +6 more
doaj   +1 more source

The Use of Poly(vinyl alcohol)-based Hydrogels in Biomedical Applications [PDF]

, 2018
Polymers have found increasing favor in biomedical applications due to the greater control that researchers can exert over their properties. Researchers have focused on the development of therapies using biologically compatible polymers due to their ...
Subramanian, Deepak
core   +1 more source

Cartilage Regeneration Characteristics of Human and Goat Auricular Chondrocytes

Frontiers in Bioengineering and Biotechnology, 2021
Although cartilage regeneration technology has achieved clinical breakthroughs, whether auricular chondrocytes (AUCs) represent optimal seed cells to achieve stable cartilage regeneration is not clear.
Mengjie Hou, Mengjie Hou, Baoshuai Bai, Baoshuai Bai, Baoxing Tian, Zheng Ci, Zheng Ci, Yu Liu, Yu Liu, Yu Liu, Guangdong Zhou, Guangdong Zhou, Guangdong Zhou, Yilin Cao, Yilin Cao   +14 more
doaj   +1 more source

Proliferation medium in three-dimensional culture of auricular chondrocytes promotes effective cartilage regeneration in vivo

Regenerative Therapy, 2019
Introduction: Cartilage regeneration have been attracted attentions because of the poor ability of cartilage tissues to regenerate. Three-dimensional (3D) culture of chondrocytes is considered to be advantageous for cartilage regeneration. Although it is
Ryuji Okubo, Yukiyo Asawa, Makoto Watanabe, Satoru Nagata, Masaki Nio, Tsuyoshi Takato, Atsuhiko Hikita, Kazuto Hoshi   +7 more
doaj   +1 more source

The chondro-osseous continuum: is it possible to unlock the potential assigned within? [PDF]

, 2018
Endochondral ossification (EO), by which long bones of the axial skeleton form, is a tightly regulated process involving chondrocyte maturation with successive stages of proliferation, maturation, and hypertrophy, accompanied by cartilage matrix ...
Adams, Aizawa, Akintoye, Amling, Bahney, Ballock, Behonick, Boegård, Brachet, Cancedda, Candeliere, Carames, Clarkin, Colnot, Colnot, Day, Dodds, Emons, Enishi, Erenpreisa, Farnum, Farnum, Felson, Galotto, Gebhard, Gerstenfeld, Gibson, Gibson, Hall, Holmbeck, Hu, Hughes, Hunter, Javaheri, Jing, Johnell, Karaplis, Kawaguchi, Kuttapitiya, Lavigne, Lian, Lieu, Mackie, Maeda, Maes, Maes, Marigo, Moskalewski, Murphy, Ono, Ortega, Park, Pottenger, Poulet, Provot, Rawlinson, Riminucci, Roach, Roach, Roach, Shah, Shapiro, Silbermann, Song, Stafford, Stickens, Thesingh, Tsang, Van der Stricht, Vortkamp, Vu, Wade-Gueye, Wang, Woolf, Yang, Yoshioka, Zelzer, Zenmyo, Zhou, Zhou   +79 more
core   +3 more sources

Bilayered scaffold with 3D printed stiff subchondral bony compartment to provide constant mechanical support for long-term cartilage regeneration

Journal of Orthopaedic Translation, 2021
Background/Objective: We seek to figure out the effect of stable and powerful mechanical microenvironment provided by Ti alloy as a part of subchondral bone scaffold on long-term cartilage regeneration.Methods: we developed a bilayered osteochondral ...
Tao Yang, Maryam Tamaddon, Le Jiang, Jing Wang, Ziyu Liu, Zhongqun Liu, Haoye Meng, Yongqiang Hu, Jianming Gao, Xuan Yang, Yanxu Zhao, Yanling Wang, Aiyuan Wang, Qiong Wu, Chaozong Liu, Jiang Peng, Xiaodan Sun, Qingyun Xue   +17 more
doaj   +1 more source

Acrylic acid plasma coated 3D Scaffolds for Cartilage tissue engineering applications [PDF]

, 2018
The current generation of tissue engineered additive manufactured scaffolds for cartilage repair shows high potential for growing adult cartilage tissue.
Cools, Pieter, De Geyter, Nathalie, Ghobeira, Rouba, Lorenzo-Moldero, Ivan, Morent, Rino, Moroni, Lorenzo, Mota, Carlos   +6 more
core   +2 more sources

Sensory nerve EP4 facilitates heterotopic ossification by regulating angiogenesis-coupled bone formation

Journal of Orthopaedic Translation
Objective: Heterotopic ossification (HO) refers to the abnormal development of bone in soft tissue rather than within bone itself. Previous research has shown that sensory nerve prostaglandin E2 receptor 4 (EP4) signaling not only governs pain perception
Rongmin Lin, Hancheng Lin, Chencheng Zhu, Jieming Zeng, Jiahui Hou, Ting Xu, Yihui Tan, Xuyou Zhou, Yuan Ma, Mankai Yang, Kuanhai Wei, Bin Yu, Hangtian Wu, Zhuang Cui   +13 more
doaj   +1 more source

Application of Cord Blood and Cord Blood-Derived Induced Pluripotent Stem Cells for Cartilage Regeneration

Cell Transplantation, 2019
Regeneration of articular cartilage is of great interest in cartilage tissue engineering since articular cartilage has a low regenerative capacity. Due to the difficulty in obtaining healthy cartilage for transplantation, there is a need to develop an ...
Yeri Alice Rim, Yoojun Nam, Ji Hyeon Ju
doaj   +1 more source

Substrate Stress Relaxation Regulates Cell‐Mediated Assembly of Extracellular Matrix

Advanced Functional Materials, EarlyView.
Silicone‐based viscoelastic substrates with tunable stress relaxation reveal how matrix mechanics regulates cellular mechanosensing and cell‐mediated matrix remodelling in the stiff regime. High stress relaxation promotes assembly of fibronectin fibril‐like structures, increased nuclear localization of YAP and formation of β1 integrin‐enriched ...
Jonah L. Voigt, Jens Timmer, Elisabetta Ada Cavalcanti‐Adam   +2 more
wiley   +1 more source