Results 91 to 100 of about 136,745 (341)
Advanced Healthcare Materials, EarlyView.Biomimetic glycosaminoglycan analog hydrogels exhibit suitable and robust mechanical properties, as well as hemocompatibility and biocompatibility, making them ideal for the embolization of intracranial aneurysms. Notably, the hydrogel's environment‐selective swelling properties enable complete blockage of the aneurysm cavity while preventing ...
Sarit S. Sivan +8 more
wiley +1 more source
Hybrid bioprinting of chondrogenically induced human mesenchymal stem cell spheroids [PDF]
, 2020 To date, the treatment of articular cartilage lesions remains challenging. A promising strategy for the development of new regenerative therapies is hybrid bioprinting, combining the principles of developmental biology, biomaterial science, and 3D ...
Asadian, Mahtab +8 more
core +2 more sources
Advanced Healthcare Materials, EarlyView.This study developed 3D‐printable THA‐Col microgels for delivering BMP‐7 cmRNA. The key result is that hMSCs transfected on the biomaterials showed BMP‐7 secretion levels comparable to pre‐transfected hMSCs, therefore introducing a cmRNA‐activated matrix to promote bone healing.
Daphne van der Heide +7 more
wiley +1 more source
Acta Orthopaedica, 2018 Background and purpose — The optimal treatment for traumatic cartilage injuries remains unknown. Contrast-enhanced MRI of cartilage (dGEMRIC) evaluates cartilage quality and a low dGEMRIC index may predict radiographic osteoarthritis (OA). The purpose of
Jon Tjörnstrand +5 more
doaj +1 more source
Use of mesenchymal stem cells seeded on the scaffold in articular cartilage repair
Inflammation and Regeneration, 2018 Articular cartilage has poor capacity for repair. Once damaged, they degenerate, causing functional impairment of joints. Allogeneic cartilage transplantation has been performed for functional recovery of articular cartilage.
Kaoru Yamagata +2 more
doaj +1 more source
The regulation of differentiation in mesenchymal stem cells [PDF]
, 2010 Peer reviewedPublisher ...
Augello, Andrea, De Bari, Cosimo
core +1 more source
Pyrophosphate‐Containing Calcium Phosphates Negatively Impact Heterotopic Bone Quality
Advanced Healthcare Materials, EarlyView.The role of calcium pyrophosphate (Ca‐PP) in heterotopic bone formation and material degradation is investigated using calcium phosphate (CaP) compositions with varying Ca‐PP content. Results show that Ca‐PP does not impede heterotopic bone formation, minimally affects CaP degradation at non‐osseous sites, and increases phagocytosis.
Martina Jolic +7 more
wiley +1 more source
Machine learning to predict mesenchymal stem cell efficacy for cartilage repair.
PLoS Computational Biology, 2020 Inconsistent therapeutic efficacy of mesenchymal stem cells (MSCs) in regenerative medicine has been documented in many clinical trials. Precise prediction on the therapeutic outcome of a MSC therapy based on the patient's conditions would provide ...
Yu Yang Fredrik Liu +3 more
doaj +1 more source
Subchondral chitosan/blood implant-guided bone plate resorption and woven bone repair is coupled to hyaline cartilage regeneration from microdrill holes in aged rabbit knees [PDF]
, 2014 SummaryObjectiveLittle is known of how to routinely elicit hyaline cartilage repair tissue in middle-aged patients. We tested the hypothesis that in skeletally aged rabbit knees, microdrill holes can be stimulated to remodel the bone plate and induce a ...
Chen, G. +3 more
core +1 more source
Advanced Healthcare Materials, EarlyView.This study presents the development of large‐scale (15 cm2) cartilage constructs with anisotropic mechanical properties using melt electrowritten (MEW) microfiber reinforced cell‐laden gelatin methacryloyl (gelMA). These constructs mimic the mechanical behavior of native cartilage, providing a suitable environment for Articular Cartilage ...
Lennard Spauwen +5 more
wiley +1 more source