Results 101 to 110 of about 148,666 (361)

Early Condylectomy: Biological Considerations [PDF]

, 2018
Objective: To describe the early treatment of two patients with unilateral condylar hyperplasia (UCH) diagnosis and therapeutic surgical protocol (early condylectomy) supported by the current biological knowledge about the development and repair of ...
Almeida, Luis Eduardo, Botero, Juliana Ruiz, López, Diego Fernando   +2 more
core   +1 more source

Management of Osteoarthritis with Avocado/Soybean Unsaponifiables. [PDF]

, 2015
Osteoarthritis (OA) is a painful and life-altering disease that severely limits the daily activity of millions of Americans, and is one of the most common causes of disability in the world. With obesity on the rise and the worlds population living longer,
Bhatti, Simi, Christiansen, Blaine, Emami, Shahin, Goudarzi, Ramin   +3 more
core   +1 more source

Articular Cartilage Repair

Science Insights, 2018
The articular cartilage repair can be achieved through different ways that is cell based repair, articular cartilage transplant, the use of micro fracture technique, the use of osteochondral autograft transplant, palliative care and the use of cell and scaffold technology.
openaire   +2 more sources

3D Soft Hydrogels Induce Human Mesenchymal Stem Cells “Deep” Quiescence

Advanced Healthcare Materials, EarlyView.
Three‐dimensional soft hydrogels mimicking the bone marrow niche induce deep quiescence in human mesenchymal stem cells. Unlike 2D culture, 3D matrices halt proliferation, regulate cell‐cycle and quiescence markers, and downregulate mTORC1 signaling, preserving stem cell phenotype and therapeutic potential ex vivo.
David Boaventura Gomes, Timo Rademakers, Ana Filipa Henriques Lourenço, Andrea Calore, Clarissa Tomasina, Denis van Beurden, Jinjie Venema, Bryan Chömpff, Hong Liu, Nicole Bouvy, Sandra Camarero‐Espinosa, Lorenzo Moroni   +11 more
wiley   +1 more source

Chronic tendon pathology: molecular basis and therapeutic implications [PDF]

, 2005
Tendons are frequently affected by chronic pain or rupture. Many causative factors have been implicated in the pathology, which until relatively recently was under-researched and poorly understood.
Riley, GP
core   +1 more source

Imaging of cartilage repair procedures

Indian Journal of Radiology and Imaging, 2014
AbstractThe rationale for cartilage repair is to prevent precocious osteoarthritis in untreated focal cartilage injuries in the young and middle-aged population. The gamut of surgical techniques, normal postoperative radiological appearances, and possible complications have been described.
Darshana Sanghvi, Mihir Munshi, Dinshaw Pardiwala   +2 more
openaire   +3 more sources

Recapitulating Endochondral Ossification for Bone Repair: From Development to Engineering Strategy

Advanced Healthcare Materials, EarlyView.
This review summarizes the developmental basis of endochondral ossification (ECO) and its applications in bone tissue engineering (BTE). It first outlines the key biological processes and signaling pathways underlying ECO, then discusses biomaterial‐based engineering strategies derived from these principles, and finally highlights future directions for
Yiqi Su, Zihao He, Qianqian Chen, Long Chen, Caiyi Wei, Zijin Zhou, Jianhao Lin, Hui Li, Dan Xing   +8 more
wiley   +1 more source

Effects of Silk-Elastin and SpheroSeev Mixture and Minced Cartilage on Cartilage Repair in Rabbit Osteochondral Defect Models

Orthopaedic Journal of Sports Medicine
Background: Autologous chondrocyte implantation, a 2-stage, costly procedure, has limitations, prompting the development of 1-step techniques utilizing autologous minced cartilage (MC).
Naofumi Hashiguchi MD, MPH, Tomoyuki Nakasa MD, PhD, Masakazu Ishikawa MD, PhD, Shingo Kawabata, Shunya Tsuji MD, Atsuo Nakamae MD, PhD, Shigeru Miyaki PhD, Nobuo Adachi MD, PhD   +7 more
doaj   +1 more source

Machine learning to predict mesenchymal stem cell efficacy for cartilage repair.

PLoS Computational Biology, 2020
Inconsistent therapeutic efficacy of mesenchymal stem cells (MSCs) in regenerative medicine has been documented in many clinical trials. Precise prediction on the therapeutic outcome of a MSC therapy based on the patient's conditions would provide ...
Yu Yang Fredrik Liu, Yin Lu, Steve Oh, Gareth J Conduit   +3 more
doaj   +1 more source

Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects

Advanced Materials, EarlyView.
Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley   +1 more source