Results 221 to 230 of about 147,512 (341)
Owing to the margination effect, rod‐shaped nanoparticles exhibit markedly enhanced co‐localization with endothelial‐adherent platelets (PLTs) under dynamic blood flow. When internalized by PLTs, rod‐shaped PNR@Res inhibit FAK and PI3K/AKT signaling in a morphology‐dependent manner, thereby disrupting their pathological crosstalk with various ...
Bin Zhang +6 more
wiley +1 more source
Enhancing the Reliability of Cartilage Repair Evaluation: A Simplified Volume-Based Approach. [PDF]
Puhakka J +8 more
europepmc +1 more source
PA30 Intrinsic repair of cartilage defects: A challenge for the future?
openalex +1 more source
Advances in Nanoenabled 3D Matrices for Cartilage Repair
Catarina Leite Pereira +2 more
openalex +1 more source
Senescent synovial intimal fibroblasts (SIF) are identified as key drivers of osteoarthritis. They promote M1 macrophage polarization and cartilage degeneration via the ANGPTL4–α5β1 axis, regulated by transcription factors EGR1 and ATF3. Pharmacological inhibition of this pathway alleviates disease, revealing SIF senescence as a promising therapeutic ...
Muhai Deng +7 more
wiley +1 more source
Adjuvant injection therapies following knee cartilage repair demonstrate heterogeneous evidence: A systematic review. [PDF]
Saráchaga Mendoza MA +4 more
europepmc +1 more source
Advances in the Regulation of Periostin for Osteoarthritic Cartilage Repair Applications
Shyh‐Jen Shih +11 more
openalex +1 more source
Multi‐Tissue Genetic Regulation of RNA Editing in Pigs
This study presents the first multi‐tissue map of RNA editing and its genetic regulation in pigs. By integrating RNA editing profiles, edQTL mapping, GWAS, and cross‐species comparisons, this work establishes RNA editing as a distinct regulatory layer linking genetic variation to complex traits, highlighting its functional and evolutionary significance.
Xiangchun Pan +21 more
wiley +1 more source
Five-Year Clinical and MRI-Based Outcomes After Cartilage Repair With or Without ACL Reconstruction: Worse Clinical Outcome after ACL Reconstruction Does not Affect Cartilage Repair Tissue Quality. [PDF]
Koenig FRM +9 more
europepmc +1 more source
Mechanical loading induces a previously unrecognized Sox9+Acan+ transitional mesenchymal cell population in the periodontal ligament that promotes osteoclastogenesis via the FGF2–FGFR2–ERK axis. Targeting this mechanoresponsive stromal population using a localized GelMA@siRNA delivery strategy attenuates pathological osteoclast overactivation and root ...
Miao Tan +9 more
wiley +1 more source

