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Emerging Strategies in Cartilage Repair and Joint Preservation. [PDF]
Focsa MA, Florescu S, Gogulescu A.
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Orthopedic Clinics of North America, 2023
Osteochondral lesions of the ankle joint are typically associated with a traumatic etiology and present with ankle pain and swelling. Conservative management yields unsatisfactory results because of the poor healing capacity of the articular cartilage. Smaller lesions (10 mm), cystic lesions, uncontained lesions, or patients who have failed prior bone ...
Mohammad T, Azam +6 more
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Osteochondral lesions of the ankle joint are typically associated with a traumatic etiology and present with ankle pain and swelling. Conservative management yields unsatisfactory results because of the poor healing capacity of the articular cartilage. Smaller lesions (10 mm), cystic lesions, uncontained lesions, or patients who have failed prior bone ...
Mohammad T, Azam +6 more
openaire +2 more sources
Cartilage Tissue and Therapeutic Strategies for Cartilage Repair
Current Molecular Medicine, 2021: High incidence of articular cartilage defects is still a major challenge in orthopedic and trauma surgery worldwide. It also has great socioeconomic effects as it is the major cause of disability in industrialized countries. This highlights the essential need for new treatments.
Sahar, Khajeh +4 more
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Physical Medicine and Rehabilitation Clinics of North America, 2000
Articular cartilage is a complex structure that, once damaged, has little capacity for permanent repair. The problem lies in the inability of the body to regenerate tissue with the appropriate macromolecular constituents and architecture of normal hyaline cartilage.
S C, Ghivizzani +3 more
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Articular cartilage is a complex structure that, once damaged, has little capacity for permanent repair. The problem lies in the inability of the body to regenerate tissue with the appropriate macromolecular constituents and architecture of normal hyaline cartilage.
S C, Ghivizzani +3 more
openaire +2 more sources
Clinical Orthopaedics and Related Research, 2001
Techniques for repairing focal articular cartilage defects are evolving from methods that induce a local stimulation of fibrocartilaginous repair to methods that will lead to a hyaline articular cartilage repair. Mosaicplasty and autologous chondrocyte implantation are examples of the latter.
R D, Coutts +5 more
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Techniques for repairing focal articular cartilage defects are evolving from methods that induce a local stimulation of fibrocartilaginous repair to methods that will lead to a hyaline articular cartilage repair. Mosaicplasty and autologous chondrocyte implantation are examples of the latter.
R D, Coutts +5 more
openaire +2 more sources
Foot and Ankle Clinics, 2003
The cause of a typical osteochondral lesion of the talus is traumatic; if symptomatic, several options exist. Because nonoperative treatment results in no more than 50% good to excellent results, the following types of surgery are in clinical use: (1) debridement and drilling, (2) osteochondral transfer, and (3) autologous chondrocyte transplantation ...
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The cause of a typical osteochondral lesion of the talus is traumatic; if symptomatic, several options exist. Because nonoperative treatment results in no more than 50% good to excellent results, the following types of surgery are in clinical use: (1) debridement and drilling, (2) osteochondral transfer, and (3) autologous chondrocyte transplantation ...
openaire +3 more sources
2016
Regenerative scaffold-based procedures have emerged in the last years as a potential therapeutic option for the treatment of chondral and osteochondral lesions. The rationale of using a scaffold is to have a temporary 3D structure of biodegradable polymers for the growth of living cells.
KON, ELIZAVETA +5 more
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Regenerative scaffold-based procedures have emerged in the last years as a potential therapeutic option for the treatment of chondral and osteochondral lesions. The rationale of using a scaffold is to have a temporary 3D structure of biodegradable polymers for the growth of living cells.
KON, ELIZAVETA +5 more
openaire +1 more source
The American Journal of Sports Medicine, 1998
Articular cartilage can tolerate a tremendous amount of intensive and repetitive physical stress. However, it manifests a striking inability to heal even the most minor injury. Both the remarkable functional characteristics and the healing limitations reflect the intricacies of its structure and biology.
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Articular cartilage can tolerate a tremendous amount of intensive and repetitive physical stress. However, it manifests a striking inability to heal even the most minor injury. Both the remarkable functional characteristics and the healing limitations reflect the intricacies of its structure and biology.
openaire +2 more sources

