Harnessing biopolymeric double network hydrogels for cartilage repair: a review of current strategies. [PDF]
Rahimkhoei V +5 more
europepmc +1 more source
Therapeutic Applications of Stimuli‐Based Release and Engineering of Extracellular Vesicles
This review summarizes the effects of endogenous and exogenous stimuli, their effects on the natural release of extracellular vesicles, as well as their uptake and release. It also gives an overview of stimuli‐responsive EVs and their therapeutic applications. Extracellular vesicles (EVs), nano‐ to microsized lipid bilayer membrane‐bound particles, are
Gloria Kemunto, Kristen Dellinger
wiley +1 more source
BMSC-Exosomes Combined With TGF-β1 Enhance Meniscal Fibrochondrocyte Function: Implications for Cartilage Repair. [PDF]
Song P +6 more
europepmc +1 more source
A bioinspired triphasic scaffold integrating 3D printed polycaprolactone and electrospun poly(lactic‐co‐glycolic acid) is developed to replicate the organization of the tendon‐to‐bone enthesis. Cyclic mechanical stimulation induces spatially defined cell morphology and lineage‐related gene expression in human mesenchymal stem cells, highlighting the ...
Ginevra Pegollo +7 more
wiley +1 more source
Models of cartilage repair with autologous mesenchymal stem cells seeded on scaffolds: a systematic narrative review. [PDF]
Wróbel M +5 more
europepmc +1 more source
Quantitative assessment and comparison of the heterogeneous chondrogenic progenitors resident in various tissues around osteoarthritic knee for cartilage repair [PDF]
V.R. Mantripragada +6 more
openalex +1 more source
Articular cartilage repair and transplantation [PDF]
J A, Buckwalter, H J, Mankin
openaire +2 more sources
Liposomal Delivery of L‐2‐Hydroxyglutarate for Targeting Epigenetic Dysregulation in Osteoarthritis
Osteoarthritis involves cartilage degeneration, inflammation, and epigenetic dysregulation. A liposomal formulation of the TET1 inhibitor L‐2‐hydroxyglutarate to overcome rapid joint clearance was developed. The formulation showed good physicochemical properties, reduced inflammatory and catabolic gene expression in chondrocytes, and alleviated ...
Denise Murgia +10 more
wiley +1 more source
Cell Co-Implantations With Chondrocytes for Cartilage Repair: A Systematic Review of In Vivo Results. [PDF]
Olijve WT +5 more
europepmc +1 more source
AAV-mediated dual-axis gene therapy to enhance cartilage repair
Kyla F. Ortved
openalex +1 more source

