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Matrices for Cartilage Repair

Clinical Orthopaedics and Related Research, 2001
Techniques for repairing focal articular cartilage defects are evolving from methods that induce a local stimulation of fibrocartilaginous repair to methods that will lead to a hyaline articular cartilage repair. Mosaicplasty and autologous chondrocyte implantation are examples of the latter.
R D, Coutts   +5 more
openaire   +2 more sources

Cartilage repair of the talus

Foot and Ankle Clinics, 2003
The cause of a typical osteochondral lesion of the talus is traumatic; if symptomatic, several options exist. Because nonoperative treatment results in no more than 50% good to excellent results, the following types of surgery are in clinical use: (1) debridement and drilling, (2) osteochondral transfer, and (3) autologous chondrocyte transplantation ...
openaire   +2 more sources

Cartilage Repair: Scaffolding

2016
Regenerative scaffold-based procedures have emerged in the last years as a potential therapeutic option for the treatment of chondral and osteochondral lesions. The rationale of using a scaffold is to have a temporary 3D structure of biodegradable polymers for the growth of living cells.
KON, ELIZAVETA   +5 more
openaire   +1 more source

Articular Cartilage Repair

The American Journal of Sports Medicine, 1998
Articular cartilage can tolerate a tremendous amount of intensive and repetitive physical stress. However, it manifests a striking inability to heal even the most minor injury. Both the remarkable functional characteristics and the healing limitations reflect the intricacies of its structure and biology.
openaire   +2 more sources

Proteoglycans and Cartilage Repair

2011
Repair of damaged articular cartilage in osteoarthritis (OA) is a clinical challenge. Because cartilage is an avascular and aneural tissue, normal mechanisms of tissue repair through recruitment of cells to the site of tissue destruction are not feasible.
Mohamed, Ouzzine   +2 more
openaire   +2 more sources

Decellularized cartilage as a prospective scaffold for cartilage repair

Materials Science and Engineering: C, 2019
Articular cartilage lacks self-healing capacity, and there is no effective therapy facilitating cartilage repair. Osteoarthritis (OA) due to cartilage defects represents large and increasing healthcare burdens worldwide. Nowadays, the generation of scaffolds to preserve bioactive factors and the biophysical environment has received increasing attention.
Chen Xia   +10 more
openaire   +2 more sources

Orthobiologics for Cartilage Repair

Clinics in Sports Medicine
Orthobiologics are substances derived from biological sources and are increasingly used in cartilage repair. Mesenchymal signaling cells (MSCs) play a crucial role in cartilage regeneration, but face challenges in clinical application. Platelet-rich plasma, concentrated bone marrow aspirate, adipose tissue, and human umbilical cord blood have all ...
Yusuf N, Mufti   +5 more
openaire   +2 more sources

Magnetic resonance imaging of cartilage and cartilage repair

Clinical Radiology, 2004
Magnetic resonance (MR) imaging of articular cartilage has assumed increased importance because of the prevalence of cartilage injury and degeneration, as well as the development of new surgical and pharmacological techniques to treat damaged cartilage.
K L, Verstraete   +6 more
openaire   +2 more sources

Cartilage biology, pathology, and repair

Cellular and Molecular Life Sciences, 2010
Osteoarthritis is one of the most common forms of musculoskeletal disease and the most prominent type of arthritis encountered in all countries. Although great efforts have been made to investigate cartilage biology and osteoarthritis pathology, the treatment has lagged behind that of other arthritides, as there is a lack of effective disease-modifying
Daniel, Umlauf   +3 more
openaire   +2 more sources

EVALUATION OF CARTILAGE INJURIES AND REPAIR

The Journal of Bone and Joint Surgery-American Volume, 2003
Articular cartilage injuries ( Fig. 1 ) are common findings during arthroscopy 1 and diagnostic imaging of the joints 2,3. While there are many techniques for the treatment of cartilage injuries, not enough is known about which lesions need treatment or about the proper treatment modality for a particular lesion. More objective data regarding cartilage
Mats, Brittberg, Carl S, Winalski
openaire   +2 more sources

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