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Articular Cartilage Repair

The American Journal of Sports Medicine, 1998
Articular cartilage can tolerate a tremendous amount of intensive and repetitive physical stress. However, it manifests a striking inability to heal even the most minor injury. Both the remarkable functional characteristics and the healing limitations reflect the intricacies of its structure and biology.
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Proteoglycans and Cartilage Repair

2011
Repair of damaged articular cartilage in osteoarthritis (OA) is a clinical challenge. Because cartilage is an avascular and aneural tissue, normal mechanisms of tissue repair through recruitment of cells to the site of tissue destruction are not feasible.
Mohamed, Ouzzine   +2 more
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Orthobiologics for Cartilage Repair

Clinics in Sports Medicine
Orthobiologics are substances derived from biological sources and are increasingly used in cartilage repair. Mesenchymal signaling cells (MSCs) play a crucial role in cartilage regeneration, but face challenges in clinical application. Platelet-rich plasma, concentrated bone marrow aspirate, adipose tissue, and human umbilical cord blood have all ...
Yusuf N, Mufti   +5 more
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Decellularized cartilage as a prospective scaffold for cartilage repair

Materials Science and Engineering: C, 2019
Articular cartilage lacks self-healing capacity, and there is no effective therapy facilitating cartilage repair. Osteoarthritis (OA) due to cartilage defects represents large and increasing healthcare burdens worldwide. Nowadays, the generation of scaffolds to preserve bioactive factors and the biophysical environment has received increasing attention.
Chen Xia   +10 more
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Magnetic resonance imaging of cartilage and cartilage repair

Clinical Radiology, 2004
Magnetic resonance (MR) imaging of articular cartilage has assumed increased importance because of the prevalence of cartilage injury and degeneration, as well as the development of new surgical and pharmacological techniques to treat damaged cartilage.
K L, Verstraete   +6 more
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EVALUATION OF CARTILAGE INJURIES AND REPAIR

The Journal of Bone and Joint Surgery-American Volume, 2003
Articular cartilage injuries ( Fig. 1 ) are common findings during arthroscopy 1 and diagnostic imaging of the joints 2,3. While there are many techniques for the treatment of cartilage injuries, not enough is known about which lesions need treatment or about the proper treatment modality for a particular lesion. More objective data regarding cartilage
Mats, Brittberg, Carl S, Winalski
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Cartilage biology, pathology, and repair

Cellular and Molecular Life Sciences, 2010
Osteoarthritis is one of the most common forms of musculoskeletal disease and the most prominent type of arthritis encountered in all countries. Although great efforts have been made to investigate cartilage biology and osteoarthritis pathology, the treatment has lagged behind that of other arthritides, as there is a lack of effective disease-modifying
Daniel, Umlauf   +3 more
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Cartilage repair: A critical review

Acta Orthopaedica Scandinavica, 1996
(1996). Cartilage repair: A critical review. Acta Orthopaedica Scandinavica: Vol. 67, No. 5, pp. 523-529.
K, Messner, J, Gillquist
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Advances in Ankle Cartilage Repair

Clinics in Podiatric Medicine and Surgery, 2017
Repair of osteochondral lesions of the talus can be difficult. Smaller lesions respond well to simple arthroscopy and microfracture, whereas larger cystic lesions may require allograft talus replacement or ankle fusions. The lesions in between are more difficult to treat.
Alan, Ng   +2 more
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Allografts in Articular Cartilage Repair

The Journal of Bone & Joint Surgery, 2006
Hyaline articular cartilage is an avascular and insensate tissue with a distinct structural organization, which provides a low-friction and wear-resistant interface for weight-bearing surface articulation in diarthrodial joints. Ideally, articular cartilage is maintained in homeostasis over the lifetime of an individual, with its biomechanical ...
Simon, Görtz, William D, Bugbee
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