Results 221 to 230 of about 76,092 (265)

Proteoglycans and Cartilage Repair

2011
Repair of damaged articular cartilage in osteoarthritis (OA) is a clinical challenge. Because cartilage is an avascular and aneural tissue, normal mechanisms of tissue repair through recruitment of cells to the site of tissue destruction are not feasible.
Mohamed, Ouzzine, Narayanan, Venkatesan, Sylvie, Fournel-Gigleux   +2 more
openaire   +2 more sources

Orthobiologics for Cartilage Repair

Clinics in Sports Medicine
Orthobiologics are substances derived from biological sources and are increasingly used in cartilage repair. Mesenchymal signaling cells (MSCs) play a crucial role in cartilage regeneration, but face challenges in clinical application. Platelet-rich plasma, concentrated bone marrow aspirate, adipose tissue, and human umbilical cord blood have all ...
Yusuf N, Mufti, Jared P, Sachs, Andrew S, Bi, Krish S, Sardesai, Adam B, Yanke, Brian J, Cole   +5 more
openaire   +2 more sources

Decellularized cartilage as a prospective scaffold for cartilage repair

Materials Science and Engineering: C, 2019
Articular cartilage lacks self-healing capacity, and there is no effective therapy facilitating cartilage repair. Osteoarthritis (OA) due to cartilage defects represents large and increasing healthcare burdens worldwide. Nowadays, the generation of scaffolds to preserve bioactive factors and the biophysical environment has received increasing attention.
Chen Xia, Sheng Mei, Chenhui Gu, Lin Zheng, Chen Fang, Yiling Shi, Kaiwei Wu, Tongtong Lu, Yongming Jin, Xianfeng Lin, Pengfei Chen   +10 more
openaire   +2 more sources

Magnetic resonance imaging of cartilage and cartilage repair

Clinical Radiology, 2004
Magnetic resonance (MR) imaging of articular cartilage has assumed increased importance because of the prevalence of cartilage injury and degeneration, as well as the development of new surgical and pharmacological techniques to treat damaged cartilage.
K L, Verstraete, F, Almqvist, P, Verdonk, G, Vanderschueren, W, Huysse, R, Verdonk, G, Verbrugge   +6 more
openaire   +2 more sources

Cartilage biology, pathology, and repair

Cellular and Molecular Life Sciences, 2010
Osteoarthritis is one of the most common forms of musculoskeletal disease and the most prominent type of arthritis encountered in all countries. Although great efforts have been made to investigate cartilage biology and osteoarthritis pathology, the treatment has lagged behind that of other arthritides, as there is a lack of effective disease-modifying
Daniel, Umlauf, Svetlana, Frank, Thomas, Pap, Jessica, Bertrand   +3 more
openaire   +2 more sources

EVALUATION OF CARTILAGE INJURIES AND REPAIR

The Journal of Bone and Joint Surgery-American Volume, 2003
Articular cartilage injuries ( Fig. 1 ) are common findings during arthroscopy 1 and diagnostic imaging of the joints 2,3. While there are many techniques for the treatment of cartilage injuries, not enough is known about which lesions need treatment or about the proper treatment modality for a particular lesion. More objective data regarding cartilage
Mats, Brittberg, Carl S, Winalski
openaire   +2 more sources

Biological Approaches for Cartilage Repair

Journal of Knee Surgery, 2009
The social impact of bone and cartilage pathologies entails high costs in terms of therapeutic treatments and loss of income. As a result, the current research trend includes preventive interventions and therapeutic solutions that can lead to an enhancement of tissue regeneration and the reduction of degenerative mechanisms. Many options have been made
Alberto, Gobbi, Lyndon, Bathan
openaire   +2 more sources

Scaffolds for Articular Cartilage Repair

Journal of Long-Term Effects of Medical Implants, 2012
Tissue engineering has been at the forefront of medical research for more than 20 years. One of the most promising applications of tissue engineering is its use in cartilage repair. A successful cartilage repair model relies on the intricate interplay between cells, scaffolds, and the environment. Dedication to this field has resulted in a wide variety
Ashley, Olson, Adam, Graver, Daniel, Grande   +2 more
openaire   +2 more sources

The Role of Periosteum in Cartilage Repair

Clinical Orthopaedics and Related Research, 2001
Periosteum, which can be grown in cell and whole tissue cultures, may meet one or more of the three prerequisites for tissue engineered cartilage repair. Periosteum contains pluripotential mesenchymal stem cells with the potential to form either cartilage or bone.
S W, O'Driscoll, J S, Fitzsimmons
openaire   +2 more sources

Advances in Ankle Cartilage Repair

Clinics in Podiatric Medicine and Surgery, 2017
Repair of osteochondral lesions of the talus can be difficult. Smaller lesions respond well to simple arthroscopy and microfracture, whereas larger cystic lesions may require allograft talus replacement or ankle fusions. The lesions in between are more difficult to treat.
Alan, Ng, Andrew, Bernhard, Kaitlyn, Bernhard   +2 more
openaire   +2 more sources