Results 141 to 150 of about 36,826 (221)

Effects of catechins, resveratrol, silymarin components and some of their conjugates on xanthine oxidase‐catalyzed xanthine and 6‐mercaptopurine oxidation

Journal of the Science of Food and Agriculture, Volume 105, Issue 5, Page 2765-2776, 30 March 2025.
Abstract BACKGROUND Over the past two decades, the global incidence of gout has markedly increased, affecting people worldwide. Considering the side effects of xanthine oxidase (XO) inhibitor drugs (e.g. allopurinol and febuxostat) used in the treatment of hyperuricemia and gout, the potential application of phytochemicals has been widely studied.
Tímea Bencsik, Orsolya Balázs, Róbert G Vida, Balázs Z Zsidó, Csaba Hetényi, Kateřina Valentová, Miklós Poór   +6 more
wiley   +1 more source

Impact of Age and Nerve Impairment Interaction on Bell's Palsy Prognosis

The Laryngoscope, EarlyView.
This study investigated the prognostic impact of the interaction between aging and nerve impairment severity in 181 patients with Bell's palsy. Although age alone was not an independent predictor, the interaction between older age (≥ 65 years) and a Nerve Excitability Test threshold difference (≥ 3.5 mA) significantly increased the risk of incomplete ...
Hiroyuki Yamada, Miyuki Oshita, Takemichi Tanaka, Shota Miyaji, Takuya Kimura, Shinji Iwata, Ryota Takagi, Naohito Hato   +7 more
wiley   +1 more source

Designing Thermally Stable DNA Hydrogels via Entropically‐Driven Acridine Intercalation

Macromolecular Rapid Communications, EarlyView.
Environmental variables are shown to systematically tune the network dynamics of entropy‐driven, acridine‐based DNA‐intercalating supramolecular hydrogels. Adjusting the buffer composition, ionic identity, and salt concentration impacts electrostatic screening and counterion release of the DNA backbone, offering a powerful handle to tune elasticity and
Shaina M. Hughes, Amy M. DiVito, Patrick F. Strobel, Pearson J. J. Franz, Matthew E. Currier, Nathan J. Oldenhuis   +5 more
wiley   +1 more source

Analysis of Carbohydrates and Glycoconjugates by Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry: An Update for 2023–2024

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley   +1 more source

Senotherapeutics for Knee Osteoarthritis

Medicinal Research Reviews, EarlyView.
ABSTRACT Osteoarthritis (OA) is a chronic disease that imposes a significant economic burden and deteriorates quality of life. Nevertheless, current therapeutic options for OA are limited to symptomatic remedies. As such, there is a high interest in novel methods for treating or preventing OA.
Ezgi Duman, Girish Pattappa, Patrick Pann, Stephan Reppenhagen, Maximilian Rudert, Peter Angele, Denitsa Docheva   +6 more
wiley   +1 more source

Cartoon [PDF]

Ultrasound in Obstetrics & Gynecology, 2008
openaire   +1 more source

Molecular Glue Degraders in Early Development for Cancer Therapy

Medicinal Research Reviews, EarlyView.
ABSTRACT Molecular glue degraders are an emerging class of small molecule allosteric modulators that induce or stabilize protein‐protein interactions, enabling targeted degradation of previously intractable proteins. By redirecting E3 ligases to recognize neosubstrates, proteins that are not typically recognized by a specific E3 ubiquitin ligase, they ...
E. Sila Ozdemir, Hyunbum Jang, Ozlem Keskin, Attila Gursoy, Ruth Nussinov   +4 more
wiley   +1 more source

Mechano‐Optical Behavior of Uniaxially Oriented Fluoropolymer Films: Ethylene Tetrafluoroethylene Copolymer (ETFE) and Tetrafluoroethylene Hexafluoropropylene‐ Vinylidene Fluoride Terpolymer (THV)

Polymer Engineering &Science, EarlyView.
Strain‐optical time slice study and evolution of microstructure via wide and small angle X‐ray scattering patterns and AFM images for uniaxially oriented THV and ETFE films at 145°C. ABSTRACT This study investigates morphological changes during the uniaxial orientation of two fluorinated polymers, ETFE and THV.
Megan Forshey, Miko Cakmak
wiley   +1 more source

Controlling Linear and Non‐Linear Mechanics in Multicomponent Hydrogels Through Programmable Supramolecular and Covalent Interactions

Journal of Polymer Science, EarlyView.
Fully synthetic, multi‐component hydrogels are engineered that possess tunable (non)‐linear mechanics by programmable supramolecular and covalent interactions. By changing the type of inter‐network interaction, the linear and non‐linear mechanics of the macroscopic hydrogel were programmed.
Martin G. T. A. Rutten, Laura Rijns, Jingyi Huang, Ruth Cardinaels, Paul H. J. Kouwer, Patricia Y. W. Dankers   +5 more
wiley   +1 more source

Using art history to explore society's changing connections with agriculture

PLANTS, PEOPLE, PLANET, EarlyView.
Food insecurity is a looming challenge that especially affects those least fortunate. Consumer food choices have a substantial impact on the sustainability of current food systems. Here, we use art as a lens through which to consider our contemporary and historical relationship to one of the world's most crucial crops, the potato, in the context of the
Edward F. Hill‐King, Martin R. McAinsh, Michael R. Roberts   +2 more
wiley   +1 more source