Results 21 to 30 of about 1,184 (187)
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Social Media Cartooning: Visual and Multimodal Metaphors in Iraqi Newspapers Cartoons
The current study explores the investigation of visual and multimodal metaphors by the use of metaphorical elements in cartoons that focus on social media networking. Thirty-two cartoons, by well-known cartoonists, are gathered from the Iraqi newspapers.
Hayder Tuma Jassim Alsaedi
doaj +1 more source
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Features of the Analysis of Human Images as Objects of Forensic Portrait Examination
The authors present an analysis of the practice of forensic portrait examinations appointed on criminal and civil cases to the Russian Federal Centre of Forensic Science of the Ministry of Justice of the Russian Federation, the objects of which have been
A. M. Zinin, V. V. Vorontsova
doaj +1 more source
Throughout the 20th century, cartoons relentlessly appeared in all sorts of newspapers, evidence of the immense cultural impact of illustrative satire long before the era of television. Many events were recorded in print, such as the Great War, the 1916 Easter Rising, women’s suffrage, the Second World War, and the Cold War.
Jane Chapman +3 more
openaire +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Victims or villains? How editorial cartoons depict the 2023 Israel – Palestine war
The study analyzed online editorial cartoons depicting the Israel-Palestine conflict through visual, symbolic, metaphorical, and textual analysis. The study reveals a prevailing anti-war sentiment across editorial cartoons, with a notable inclination ...
Gondwe Gregory, Walcott Carolyn
doaj +1 more source
Multimodal Discourse Features in Selected Nigerian Political Cartoons
Political cartoons in Nigerian society serve as tools for political commentary and social critique. This research investigates the socio-political impact of visual and linguistic strategies in selected Nigerian political cartoons, addressing a ...
Esther Olajumoke Adeagbo +1 more
doaj +1 more source

