Results 21 to 30 of about 19,982 (254)
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Cartoons in Romanian humorous news
The European Journal of Humour Research, 2020 Studying cartoons in Romanian humorous news is a great way to underline the diversity of humour’s mechanisms and construction. The common topic of cartoons in Romanian media is politics, but there are also a great number of cartoons exploring subjects ...
Nicoleta Andreea Soare
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Features of the Analysis of Human Images as Objects of Forensic Portrait Examination
Теория и практика судебной экспертизы, 2022 The authors present an analysis of the practice of forensic portrait examinations appointed on criminal and civil cases to the Russian Federal Centre of Forensic Science of the Ministry of Justice of the Russian Federation, the objects of which have been
A. M. Zinin, V. V. Vorontsova
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Social Media Cartooning: Visual and Multimodal Metaphors in Iraqi Newspapers Cartoons
آداب الكوفةThe current study explores the investigation of visual and multimodal metaphors by the use of metaphorical elements in cartoons that focus on social media networking. Thirty-two cartoons, by well-known cartoonists, are gathered from the Iraqi newspapers.
Hayder Tuma Jassim Alsaedi
doaj +1 more source
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Disraeli and “One Nation” in British cartoons, 1914-2016
Revue Française de Civilisation Britannique, 2023 This paper analyzes the cartoons featuring Benjamin Disraeli after his death and the concept of “One Nation”. It shows that Disraeli remained through the 20th century a persona which British cartoonists recurringly made use of, although Churchill, and to
Philippe Vervaecke
doaj +1 more source
FEBS Open Bio, EarlyView.KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura +19 more
wiley +1 more source