Results 1 to 10 of about 38,527 (248)
Carvedilol inhibits the cardiostimulant and thermogenic effects of MDMA in humans : lost in translation [PDF]
We greatly appreciate the comments offered by Drs Rolle, Takematsu, and Hoffman and the opportunity to put our work into a wider perspective. We share the view that our work does not reflect the clinical situation but rather provides a proof of mechanism
Boehrer +26 more
core +3 more sources
S‐ and R‐Carvedilol Prevent Benzo(a)pyrene‐Induced Lung Carcinogenesis [PDF]
Lung cancer is the most common and deadly type of cancer. Our previous study showed that carvedilol, a β‐blocker, can prevent lung cancer induced by benzo(a)pyrene [B(a)P].
Ayaz Shahid +3 more
doaj +2 more sources
Post-carvedilol myocardial function in cats with obstructive hypertrophic cardiomyopathy [PDF]
IntroductionHypertrophic cardiomyopathy (HCM) is the most prevalent cardiac disease in cats, and one phenotype includes obstructive HCM with dynamic left ventricular outflow tract obstruction (DLVOTO). Myocardial function has been reported to be lower in
Takahiro Saito +9 more
doaj +2 more sources
Optimization and Validation of an HPLC Method for the Analysis of Carvedilol and Impurities. [PDF]
Yuan L +7 more
europepmc +3 more sources
Background and purpose: The study was aimed at validating a simple, rapid, and low-cost LC-MS/MS method for carvedilol and 4/-hydroxyphenyl carvedilol assay in human plasma. The validated method was applied to investigate the pharmacokinetics after a low
Wanna Eiamart +5 more
doaj +1 more source
Effect of Carvedilol on Survival in Severe Chronic Heart Failure [PDF]
Milton Packer +2 more
exaly +2 more sources
Solid dosage forms based on hypromellose (HPMC) with prolonged/extended drug release are very important from the research and industrial viewpoint. In the present research, the influence of selected excipients on carvedilol release performance from HPMC ...
Tadej Ojsteršek +2 more
doaj +1 more source
The β-blocker Nebivolol Is a GRK/β-arrestin Biased Agonist [PDF]
Nebivolol, a third generation β-adrenoceptor (β-AR) antagonist (β-blocker), causes vasodilation by inducing nitric oxide (NO) production. The mechanism via which nebivolol induces NO production remains unknown, resulting in the genesis of much of the ...
Andresen, Bradley T. +9 more
core +11 more sources
Background Carvedilol, the anti-hypertensive drug, has poor bioavailability when administered orally. Ethosomes-mediated transdermal delivery is considered a potential route of administration to increase the bioavailability of carvedilol.
Padmanabha Rao Amarachinta +5 more
doaj +1 more source

