Results 41 to 50 of about 14,835 (171)

Carvedilol Exerts Cardioprotective Effects Against Doxorubicin Toxicity via Autophagy Modulation and Energetics Restoration

Pharmaceuticals
Background/Objectives: Carvedilol is an adrenergic blocker FDA-approved to improve outcomes in heart failure with reduced ejection fraction. Clinical trials examining whether carvedilol may be cardioprotective in the setting of cancer therapy-induced ...
Asma Boukhalfa, Pei-Tsz Shin, Dawn M. Meola, Ada Yu, Amene Majidipur, Annie Showers, Dylan A. Valencia, Emmanuella F. Akomeah-Sirleaf, Jenica N. Upshaw, Cheryl A. London, Iris Z. Jaffe, David E. Sosnovik, Lakshmi Pulakat, Vicky K. Yang, Howard H. Chen   +14 more
doaj   +1 more source

ALPHA1-ADRENERGIC RECEPTOR BLOCKING ACTION OF CARVEDILOL CONTRIBUTES TO TACKLING DEXAMETHASONE-INDUCED INSULIN RESISTANCE AND TO A LESSER EXTENT HEPATIC DAMAGE [PDF]

Bulletin of Pharmaceutical Sciences. Assiut University
Insulin resistance is a well-established risk factor for serious health problems, including type 2 diabetes, cardiovascular disease, and stroke. Carvedilol has been documented to improve insulin sensitivity, ameliorate hyperlipidemia, and reduce the risk
Mohamed Hafez, Enssaf Ahmad, Mona Mahmoud, Islam Ibrahim   +3 more
doaj   +1 more source

Sleep characteristics and self‐reported sleep quality in the oldest‐old: Results from a prospective longitudinal cohort study

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Little is known about the correlation between subjective perception and objective measures of sleep quality in particular in the oldest‐old. The aim of this study was to perform longitudinal home sleep monitoring in this age group, and to correlate results with self‐reported sleep quality.
Hugo Saner, Kevin Möri, Narayan Schütz, Philipp Buluschek, Tobias Nef   +4 more
wiley   +1 more source

Endothelial Phenotype Evoked by Low Dose Carvedilol in Pulmonary Hypertension

Frontiers in Cardiovascular Medicine, 2018
Background: The therapeutic benefits of β-blockers are well established in left heart failure. The Pulmonary Arterial Hypertension Treatment with Carvedilol for Heart Failure [PAHTCH] study showed safety and possible benefit of carvedilol in pulmonary ...
Hoi I Cheong, Samar Farha, Margaret M. Park, James D. Thomas, Didem Saygin, Suzy A. A. Comhair, Jacqueline Sharp, Jacqueline Sharp, Kristin B. Highland, W. H. Wilson Tang, W. H. Wilson Tang, Serpil C. Erzurum, Serpil C. Erzurum   +12 more
doaj   +1 more source

Maternal nutrition as a key determinant of placental and developing blood–brain barrier xenobiotic protective functions

The Journal of Physiology, EarlyView.
Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor, Nycolle I. S. Souza, Bruno G. Anjos, Stephen G. Matthews, Enrrico Bloise   +4 more
wiley   +1 more source

EVALUATION OF CARVEDILOL EFFECTS ON THE BASIC DATA OF LEFT VENTRICLE SYSTOLIC AND DIASTOLIC FUNCTION AFTER ACUTE MYOCARDIAL INFARCTION

Российский кардиологический журнал, 2001
We have examinated 106 patients with primary acute myocardial Q-infarction. Favourable effects of carvedilol on basic parameters of central, intracardial and peripheral hemodynamic was identificated.
L. N. Mingazetdinova, L. F. Maxiutova, L. A. Valeeva, A. F. Maxiutova, M. E. Kanshina, V. N. Golubkova   +5 more
doaj  

S‐ and R‐Carvedilol Prevent Benzo(a)pyrene‐Induced Lung Carcinogenesis

Thoracic Cancer
Lung cancer is the most common and deadly type of cancer. Our previous study showed that carvedilol, a β‐blocker, can prevent lung cancer induced by benzo(a)pyrene [B(a)P].
Ayaz Shahid, Steven Yeung, Bradley T. Andresen, Ying Huang   +3 more
doaj   +1 more source

Comparison of the Preventive Effects of Carvedilol and Nebivolol on Kidney Ischemia Reperfusion Injury

Turkish Journal of Nephrology, 2020
Objective: To compare the ameliorating effects of carvedilol and nebivolol on kidney Ischemia/Reperfusion Injury (IRI). Materials and Methods: A total of 24 rats were separated into 4 groups.
Murat Küçük, Özer Ural Çakıcı, İpek Işık Gönül, Mustafa Kavutçu, Selim Turgay Arınsoy   +4 more
doaj   +1 more source

Systemic medications associate with surgically treated cataract among adults over 50 years in Finland

Acta Ophthalmologica, Volume 104, Issue 6, Page e630-e647, September 2026.
Abstract Purpose To identify associations between systemic drugs and cataract surgery in Finland. Methods A historic cohort study based on administrative data. Endpoint event was cataract surgery. Use of drugs in question was based on redeemed prescriptions and consisted of 156 drugs.
Antti Riikonen, Jari Haukka, Tuomas Lilius, Sirpa Loukovaara   +3 more
wiley   +1 more source

Impella‐Assisted High‐Risk Percutaneous Coronary Intervention in Cardiogenic Shock With Low‐Flow, Low‐Gradient Aortic Stenosis and Multivessel Coronary Artery Disease: A Case Report

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Patients with cardiogenic shock, low‐flow, low‐gradient aortic stenosis, and multivessel coronary artery disease who are ineligible for surgery present a major therapeutic challenge. Percutaneous mechanical circulatory support may facilitate revascularization in this high‐risk population. A 69‐year‐old man presented after a mechanical fall and
Douni Roger, Waleed Shaker, Zan Siddiqi, George Abela   +3 more
wiley   +1 more source