Results 41 to 50 of about 790 (114)

Oral delivery of the non-β-blocking R-carvedilol enantiomer for skin cancer chemoprevention in SKH-1 mice

AAPS Open
Purpose Skin cancer remains the most prevalent cancer worldwide with its incidence continuously rising. Previous studies have demonstrated the efficacy of the β-blocker carvedilol and its non-β-blocking enantiomer R-carvedilol in mitigating UV-induced ...
Pabitra K. Sardar, Steven Yeung, Ruby Tow, Jacqueline Luga, Matthew Huang, Ayaz Shahid, Bradley T. Andresen, Ying Huang   +7 more
doaj   +1 more source

ALPHA1-ADRENERGIC RECEPTOR BLOCKING ACTION OF CARVEDILOL CONTRIBUTES TO TACKLING DEXAMETHASONE-INDUCED INSULIN RESISTANCE AND TO A LESSER EXTENT HEPATIC DAMAGE [PDF]

Bulletin of Pharmaceutical Sciences. Assiut University
Insulin resistance is a well-established risk factor for serious health problems, including type 2 diabetes, cardiovascular disease, and stroke. Carvedilol has been documented to improve insulin sensitivity, ameliorate hyperlipidemia, and reduce the risk
Mohamed Hafez, Enssaf Ahmad, Mona Mahmoud, Islam Ibrahim   +3 more
doaj   +1 more source

Evaluation of a Point‐of‐Care Viscoelastic Coagulation Monitor (VCM Vet) and Thromboelastography (TEG) in Bonobos (Pan paniscus)

Journal of Medical Primatology, Volume 55, Issue 4, August 2026.
ABSTRACT Introduction Bonobos (Pan paniscus) are endangered and uncommon in managed care. Prothrombotic and hypofibrinolytic states are encountered with cardiovascular disease, ischemic stroke, and neoplasia. Materials and Methods Twelve bonobos from one institution were evaluated during anesthetized exams.
Megan M. Roeder, Priya Bapodra‐Villaverde, Lauren E. Mumm, Alex M. Lynch, Laura R. Culbreth, Megan L. Cabot, Timothy A. Georoff, Larry J. Minter   +7 more
wiley   +1 more source

S‐ and R‐Carvedilol Prevent Benzo(a)pyrene‐Induced Lung Carcinogenesis

Thoracic Cancer
Lung cancer is the most common and deadly type of cancer. Our previous study showed that carvedilol, a β‐blocker, can prevent lung cancer induced by benzo(a)pyrene [B(a)P].
Ayaz Shahid, Steven Yeung, Bradley T. Andresen, Ying Huang   +3 more
doaj   +1 more source

Comparison of the Preventive Effects of Carvedilol and Nebivolol on Kidney Ischemia Reperfusion Injury

Turkish Journal of Nephrology, 2020
Objective: To compare the ameliorating effects of carvedilol and nebivolol on kidney Ischemia/Reperfusion Injury (IRI). Materials and Methods: A total of 24 rats were separated into 4 groups.
Murat Küçük, Özer Ural Çakıcı, İpek Işık Gönül, Mustafa Kavutçu, Selim Turgay Arınsoy   +4 more
doaj   +1 more source

The quantitative impact of metabolism‐inhibiting drugs on the occurrence of adverse drug reactions—A backward selection approach

British Journal of Clinical Pharmacology, Volume 92, Issue 7, Page 2203-2211, July 2026.
Abstract Aim The quantitative effect of several inhibitory drugs on the development of adverse drug reactions (ADRs) is currently difficult to estimate. Our aim was to identify metabolic pathways, which, when inhibited, increase the risk for certain ADRs, and to use this system to consider comedication at individual level. Methods Data of a prospective
Judith Berres, Justyna Wozniak, Hannah Fölsch, Anja Knueppel‐Ruppert, Verena Graeff, Andrea Kriegisch‐Stumpf, Harald Dormann, Julia C. Stingl, Katja S. Just   +8 more
wiley   +1 more source

EVALUATION OF CARVEDILOL EFFECTS ON THE BASIC DATA OF LEFT VENTRICLE SYSTOLIC AND DIASTOLIC FUNCTION AFTER ACUTE MYOCARDIAL INFARCTION

Российский кардиологический журнал, 2001
We have examinated 106 patients with primary acute myocardial Q-infarction. Favourable effects of carvedilol on basic parameters of central, intracardial and peripheral hemodynamic was identificated.
L. N. Mingazetdinova, L. F. Maxiutova, L. A. Valeeva, A. F. Maxiutova, M. E. Kanshina, V. N. Golubkova   +5 more
doaj  

Retroperitoneal Extra‐Adrenal Paraganglioma Presenting With Secondary Amenorrhea and Hypertension in an Adolescent: A Rare Case From Sub‐Saharan Africa

Clinical Case Reports, Volume 14, Issue 7, July 2026.
ABSTRACT Extra‐adrenal paragangliomas are rare neuroendocrine tumors that may cause hypertension and reproductive dysfunction in adolescents. We report a 16‐year‐old girl with uncontrolled hypertension and secondary amenorrhea caused by a functional Organ of Zuckerkandl paraganglioma.
Getasew Kassaw Alemu, Ibraist Yohannes Haileyesus, Hirsi Haahi Ahmed, Ahmednasir Abdi Hasan, Mubarek Abdi Mohamed   +4 more
wiley   +1 more source

Carvedilol prevents impairment of the counterregulatory response in recurrently hypoglycaemic diabetic rats

Endocrinology, Diabetes & Metabolism, 2021
Aim It has been suggested that repeated activation of the adrenergic system during antecedent episodes of hypoglycaemia contributes to the development of counterregulatory failure.
Rawad Farhat, Eliane deSantana‐Van Vliet, Gong Su, Levi Neely, Thea Benally, Owen Chan   +5 more
doaj   +1 more source

Prescribing Caution: A Critique of OpenEvidence to Answer Medication‐Related Questions

JACCP: JOURNAL OF THE AMERICAN COLLEGE OF CLINICAL PHARMACY, Volume 9, Issue 7, July 2026.
ABSTRACT OpenEvidence is a newer medical large language model (LLM) that is growing in use among health professionals and students for clinical care and research. This paper provides an overview of existing literature on the accuracy of using OpenEvidence to answer clinical questions.
Jessica M. Bergsbaken, Paije Wilson, Susan Vandagriff, Leslie Christensen, Lia Vellardita   +4 more
wiley   +1 more source