Results 51 to 60 of about 19,471 (205)

Topically Applied Carvedilol Attenuates Solar Ultraviolet Radiation Induced Skin Carcinogenesis [PDF]

, 2017
In previous studies, the β-blocker carvedilol inhibited EGF-induced epidermal cell transformation and chemical carcinogen-induced mouse skin hyperplasia.
Sherry Liang, Yeung, Steven, Kristan H. Cleveland, Huang, Kevin M, Robert Orlando, Frank L. Meyskens, Bradley T. Andresen, Steven Yeung, Oiyemhonlan, Etuajie, Liang, Sherry, Parsa, Cyrus, Etuajie Oiyemhonlan, Ying Huang, Kevin M. Huang, Cleveland, Kristan H, Orlando, Robert, Cyrus Parsa, Huang, Ying, Meyskens, Frank L, Andresen, Bradley T   +19 more
core   +1 more source

Inhibitory effect of carvedilol on bedaquiline metabolism in vitro and in vivo [PDF]

PeerJ
Bedaquiline has recently been approved for the treatment of multidrug-resistant tuberculosis. Carvedilol is a cardiovascular medication extensively used in the treatment of heart failure and hypertension.
Qingqing Li, Wanshu Li, Jie Chen, Hangjuan Lin, Cixia Zhou   +4 more
doaj   +2 more sources

Heart failure medication to prevent cancer therapy–related cardiac dysfunction: A narrative review

British Journal of Pharmacology, EarlyView.
Advances in oncological therapies have improved cancer survival but also have increased the clinical incidence of cancer therapy–related cardiac dysfunction (CTRCD), a spectrum of conditions ranging from subclinical biomarker or strain abnormalities to progressive heart failure and cardiogenic shock.
Fabian Voß, Paul Goerke, Malte Kelm, Amin Polzin   +3 more
wiley   +1 more source

Objectively measured medication adherence using assays for carvedilol and enalaprilat in patients with heart failure in Mozambique and Nigeria

, 2023
Background: Poor medication adherence leads to poor health outcomes and increased healthcare costs among patients with heart failure (HF). This study aimed to objectively assess medication adherence by measuring carvedilol and enalaprilat plasma ...
Gebreyesus, Manna Semere, Charle Andre Viljoen, Julius Chacha Mwita, Paolo Denti, Hoevelmann, Julian, Damasceno, Albertino, Julian Hoevelmann, Wiesner, Lubbe, Ana Olga Mocumbi, Manna Semere Gebreyesus, Gad Cotter, Andre Joubert, Stewart, Simon, Maartens, Gary, Lubbe Wiesner, Gary Maartens, Beth Davison, Viljoen, Charle Andre, Roeland Wasmann, Saidu, Hadiza, Phumla Sinxadi, Mocumbi, Ana Olga, Karen Sliwa, Sani, Mahmoud Umar, Albertino Damasceno, Denti, Paolo, Wasmann, Roeland, Hadiza Saidu, Joubert, Andre, Sinxadi, Phumla, Mwita, Julius Chacha, Simon Stewart, Mahmoud Umar Sani, et al.   +33 more
core   +1 more source

Oral delivery of the non-β-blocking R-carvedilol enantiomer for skin cancer chemoprevention in SKH-1 mice

AAPS Open
Purpose Skin cancer remains the most prevalent cancer worldwide with its incidence continuously rising. Previous studies have demonstrated the efficacy of the β-blocker carvedilol and its non-β-blocking enantiomer R-carvedilol in mitigating UV-induced ...
Pabitra K. Sardar, Steven Yeung, Ruby Tow, Jacqueline Luga, Matthew Huang, Ayaz Shahid, Bradley T. Andresen, Ying Huang   +7 more
doaj   +1 more source

Synthesis and Characterization of Carvedilol-Etched Halloysite Nanotubes Composites with Enhanced Drug Solubility and Dissolution Rate

Molecules, 2023
Carvedilol is a poorly water-soluble drug employed to treat chronic heart failure. In this study, we synthesize new carvedilol-etched halloysite nanotubes (HNTs) composites to enhance solubility and dissolution rate.
Lauretta Maggi, Claudia Urru, Valeria Friuli, Chiara Ferrara, Debora Maria Conti, Giovanna Bruni, Doretta Capsoni   +6 more
doaj   +1 more source

Metabolic remodelling in anthracycline cardiotoxicity: mechanisms and therapeutic insights

British Journal of Pharmacology, EarlyView.
Cardiac metabolic remodelling in anthracycline‐induced cardiomyopathy and metabolically oriented cardioprotective strategies. Schematic representation of substrate utilization, mitochondrial bioenergetic function and metabolic flexibility in the healthy heart, in anthracycline‐induced cardiomyopathy and under potential cardioprotective interventions ...
Giulia Guerra, Francesco Niro, Marco Mergiotti, Giovanni Gavatorta, Emilio Hirsch, Alessandra Ghigo   +5 more
wiley   +1 more source

Role of cytochrome P450 2D6 genetic polymorphism in carvedilol hydroxylation in vitro

, 2016
Zhe Wang,1,* Li Wang,2,3,* Ren-ai Xu,4 Yun-yun Zhan,2 Cheng-ke Huang,1 Da-peng Dai,5 Jian-ping Cai,5 Guo-xin Hu2 1Department of Pharmacy, The Second Affiliated Hospital & Yuying Children’s Hospital of Wenzhou Medical University, 2Department of
Cai JP, Jian-ping Cai, Ren-ai Xu, Guo-xin Hu, Hu GX, Da-peng Dai, Huang CK, Cheng-ke Huang, Yun-yun Zhan, Wang L, Dai DP, Li Wang, Zhan YY, Wang Z, Xu RA, Zhe Wang   +15 more
core   +1 more source

ALPHA1-ADRENERGIC RECEPTOR BLOCKING ACTION OF CARVEDILOL CONTRIBUTES TO TACKLING DEXAMETHASONE-INDUCED INSULIN RESISTANCE AND TO A LESSER EXTENT HEPATIC DAMAGE [PDF]

Bulletin of Pharmaceutical Sciences. Assiut University
Insulin resistance is a well-established risk factor for serious health problems, including type 2 diabetes, cardiovascular disease, and stroke. Carvedilol has been documented to improve insulin sensitivity, ameliorate hyperlipidemia, and reduce the risk
Mohamed Hafez, Enssaf Ahmad, Mona Mahmoud, Islam Ibrahim   +3 more
doaj   +1 more source

Sleep characteristics and self‐reported sleep quality in the oldest‐old: Results from a prospective longitudinal cohort study

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Little is known about the correlation between subjective perception and objective measures of sleep quality in particular in the oldest‐old. The aim of this study was to perform longitudinal home sleep monitoring in this age group, and to correlate results with self‐reported sleep quality.
Hugo Saner, Kevin Möri, Narayan Schütz, Philipp Buluschek, Tobias Nef   +4 more
wiley   +1 more source