Results 61 to 70 of about 14,835 (171)

Left Atrial Coupling Indexes as New Mortality Predictors in Chronic Chagas Disease

Echocardiography, Volume 43, Issue 8, August 2026.
Echocardiographic left atrial coupling indexes are promising prognostic markers of dismal outcome in Chagas disease. They were associated with all‐cause mortality independent from age, sex, and echocardiographic indexes, including LV ejection fraction, supporting their potential clinical relevance.
Roberto M. Saraiva, Mauro Felippe F. Mediano, Henrique H. Veloso, Marcelo T. Holanda, Andréa R. Costa   +4 more
wiley   +1 more source

Post-carvedilol myocardial function in cats with obstructive hypertrophic cardiomyopathy

Frontiers in Veterinary Science
IntroductionHypertrophic cardiomyopathy (HCM) is the most prevalent cardiac disease in cats, and one phenotype includes obstructive HCM with dynamic left ventricular outflow tract obstruction (DLVOTO). Myocardial function has been reported to be lower in
Takahiro Saito, Takahiro Saito, Ryohei Suzuki, Yunosuke Yuchi, Yunosuke Yuchi, Haru Fukuoka, Shuji Satomi, Shuji Satomi, Takahiro Teshima, Hirotaka Matsumoto   +9 more
doaj   +1 more source

Characterization of Usage Patterns of Drugs Suspected to Cause Adverse Drug Reactions in Older Hospitalized Patients

Geriatrics &Gerontology International, Volume 26, Issue 8, August 2026.
ABSTRACT Aim This study aimed to characterize the usage patterns of drugs suspected to cause adverse drug reactions (ADRs) in older hospitalized patients. Methods Medical records of older adults admitted to the Department of Geriatrics and Hypertension at Osaka University Hospital from September 2014 to August 2021 were reviewed.
Mizuki Katsuhisa, Shota Hamada, Chie Hamaie, Yuko Takeshita, Kasumi Ikuta, Yuichiro Saizen, Eriko Koujiya, Yoichi Takami, Koichi Yamamoto, Yasushi Takeya   +9 more
wiley   +1 more source

β3‐AR/β‐arrestin2 Interaction Triggers Cardiac Fibrosis Through JNK/c‐Jun Pathway in Cardiac Fibroblasts

Journal of Cellular and Molecular Medicine, Volume 30, Issue 15, August 2026.
ABSTRACT Myocardial fibrosis (MF) is a critical pathological substrate of heart failure (HF), and β3‐adrenergic receptor (β3‐AR) has been implicated in cardiac remodelling with controversial roles. This study aimed to clarify the pro‐fibrotic mechanism of β3‐AR in cardiac fibroblasts and its association with β‐arrestin2‐mediated biased activation ...
Zhongcheng Xu, Min Zhu, Chun Zhou, Juncang Duan, Jian Ding, Jun Liu, Xuan Ying, Jie Wu, Yang Dong, Wenbiao Wang, Zhaohui Qiu   +10 more
wiley   +1 more source

Endothelial function is unaffected by changing between carvedilol and metoprolol in patients with heart failure-a randomized study

Cardiovascular Diabetology, 2011
Background Carvedilol has been shown to be superior to metoprolol tartrate to improve clinical outcomes in patients with heart failure (HF), yet the mechanisms responsible for these differences remain unclear.
Køber Lars, Major-Pedersen Atheline, Rask-Madsen Christian, Christiansen Buris, Raunsø Jakob, Hermann Thomas, Falskov Britt, Torp-Pedersen Christian, Dominguez Helena   +8 more
doaj   +1 more source

Evaluation of a Point‐of‐Care Viscoelastic Coagulation Monitor (VCM Vet) and Thromboelastography (TEG) in Bonobos (Pan paniscus)

Journal of Medical Primatology, Volume 55, Issue 4, August 2026.
ABSTRACT Introduction Bonobos (Pan paniscus) are endangered and uncommon in managed care. Prothrombotic and hypofibrinolytic states are encountered with cardiovascular disease, ischemic stroke, and neoplasia. Materials and Methods Twelve bonobos from one institution were evaluated during anesthetized exams.
Megan M. Roeder, Priya Bapodra‐Villaverde, Lauren E. Mumm, Alex M. Lynch, Laura R. Culbreth, Megan L. Cabot, Timothy A. Georoff, Larry J. Minter   +7 more
wiley   +1 more source

Effect of particle size on oral absorption of carvedilol nanosuspensions: in vitro and in vivo evaluation

International Journal of Nanomedicine, 2015
Dandan Liu,1 Hao Pan,2 Fengwei He,1 Xiaoyu Wang,3 Jinyu Li,3 Xinggang Yang,3 Weisan Pan31Department of Pharmaceutical Engineering, School of Biomedical and Chemical Engineering, Liaoning Institute of Science and Technology, Benxi, People’s Republic
Liu DD, Pan H, He FW, Wang XY, Li JY, Yang XG, Pan WS   +6 more
doaj  

Catecholamines Activate a Tumour Progression Program in Differentiated Tumour Hepatocytes

Liver International, Volume 46, Issue 8, August 2026.
ABSTRACT Background and Aims The sympathetic nervous system is involved in the progression and aggressiveness of several cancers, including hepatocellular carcinoma (HCC). However, the specific effects of sympathetic innervation and catecholamines on tumour hepatocyte behaviour remain poorly understood.
Elise Lelou, Claudine Rauch, Hélène Dubois‐Pot‐Schneider, Marjorie Dufresne, Abolfazl Zekri Yazdi, Maelle Guillout, Luis Cano, Lise Desquilles, Nicolas Nesseler, Marc Bourgeois, Claude Bendavid, Julie Massart, Orlando Musso, Anne Corlu, Caroline Aninat   +14 more
wiley   +1 more source

Changes in SSM Assessed via 100 Hz‐VCTE Are Associated With Acute HVPG‐Response to i.v. Propranolol: A European Multicentre Study

Liver International, Volume 46, Issue 8, August 2026.
ABSTRACT Background The acute hepatic venous pressure gradient (HVPG)‐response to i.v. propranolol predicts outcomes in patients with advanced chronic liver disease (ACLD) and clinically significant portal hypertension (CSPH). While non‐invasive tests (NIT) to monitor non‐selective beta‐blocker (NSBB)‐induced HVPG changes are lacking, spleen stiffness ...
Paul Thöne, Dario Saltini, Joana Calvão, Lorenz Balcar, Tomas Guasconi, Georg Semmler, Paula Höfinger, Barbara Datterl, Albert Friedrich Stättermayer, Michael Trauner, Thomas Reiberger, José Presa, Filippo Schepis, Mattias Mandorfer, Mathias Jachs   +14 more
wiley   +1 more source

Nano and Microparticulate Chitosan Based System for Formulation of Carvedilol Rapid Melt Tablet

Advanced Pharmaceutical Bulletin, 2015
Purpose: In the present study rapid melt tablets (RMT’s) of carvedilol were prepared by using ionotropic-gelated chitosan nanoparticles using a spray-drying method.
Ravindra Patil, Vishal Pande, Raju Sonawane   +2 more
doaj   +1 more source