Results 11 to 20 of about 44,151 (306)

A Novel Mechanism of Carvedilol Efficacy for Rosacea Treatment: Toll-Like Receptor 2 Inhibition in Macrophages

open access: yesFrontiers in Immunology, 2021
BackgroundRosacea, a chronic inflammatory skin disorder etiologically associated with immune cells and the antibacterial peptide cathelicidin LL-37, can be effectively treated by oral carvedilol administration.ObjectiveTo investigate the molecular ...
Jiawen Zhang   +11 more
doaj   +2 more sources

Is carvedilol superior to propranolol in patients with cirrhosis with portal hypertension: a systematic and meta-analysis [PDF]

open access: yesDrugs in Context
Background: Carvedilol has shown greater potency than propranolol as a β-blocker in managing cardiac conditions. However, its efficacy in reducing portal hypertension (PHTN) in patients with cirrhosis remains unclear.
Siddheesh Rajpurohit   +4 more
doaj   +2 more sources

Inhibitory effect of carvedilol on bedaquiline metabolism in vitro and in vivo [PDF]

open access: yesPeerJ
Bedaquiline has recently been approved for the treatment of multidrug-resistant tuberculosis. Carvedilol is a cardiovascular medication extensively used in the treatment of heart failure and hypertension.
Qingqing Li   +4 more
doaj   +3 more sources

Endothelial function is unaffected by changing between carvedilol and metoprolol in patients with heart failure-a randomized study [PDF]

open access: yesCardiovascular Diabetology, 2011
Background Carvedilol has been shown to be superior to metoprolol tartrate to improve clinical outcomes in patients with heart failure (HF), yet the mechanisms responsible for these differences remain unclear.
Køber Lars   +8 more
doaj   +5 more sources

Effect of Carvedilol on Survival in Severe Chronic Heart Failure [PDF]

open access: bronzeNew England Journal of Medicine, 2001
Milton Packer   +13 more
openalex   +2 more sources

Carvedilol in the treatment of chronic heart failure: Lessons from The Carvedilol Or Metoprolol European Trial [PDF]

open access: yesVascular Health and Risk Management, 2007
Britt Kveiborg, Atheline Major-Petersen, Buris Christiansen, Christian Torp-PedersenDepartment of Cardiology, Bispebjerg University Hospital, Copenhagen, DenmarkAbstract: Beta-blockers have been shown to improve survival in patients with chronic heart ...
Britt Kveiborg   +3 more
doaj   +3 more sources

Carvedilol as the new non‐selective beta‐blocker of choice in patients with cirrhosis and portal hypertension

open access: yesLiver international (Print), 2023
Portal hypertension (PH) is the most common complication ofcirrhosis and represents the main driver of hepatic decompensation. The overarching goal of PH treatments in patients with compensated cirrhosis is to reduce the risk of hepatic decompensation (i.
L. Turco   +3 more
semanticscholar   +1 more source

The β-Blocker Carvedilol Prevents Benzo(a)pyrene-Induced Lung Toxicity, Inflammation and Carcinogenesis

open access: yesCancers, 2023
Simple Summary Benzo(a)pyrene is a ubiquitously present environmental contaminant that induces lung cancer after being converted into active metabolites via aryl hydrocarbon receptor (AhR)-mediated metabolic activation.
A. Shahid   +6 more
semanticscholar   +1 more source

A simple LC-MS/MS method for pharmacokinetic study of carvedilol and 4/-hydroxyphenyl carvedilol at a low dose

open access: yesResearch in Pharmaceutical Sciences, 2022
Background and purpose: The study was aimed at validating a simple, rapid, and low-cost LC-MS/MS method for carvedilol and 4/-hydroxyphenyl carvedilol assay in human plasma. The validated method was applied to investigate the pharmacokinetics after a low
Wanna Eiamart   +5 more
doaj   +1 more source

Comparative Study of Selected Excipients’ Influence on Carvedilol Release from Hypromellose Matrix Tablets

open access: yesPharmaceutics, 2023
Solid dosage forms based on hypromellose (HPMC) with prolonged/extended drug release are very important from the research and industrial viewpoint. In the present research, the influence of selected excipients on carvedilol release performance from HPMC ...
Tadej Ojsteršek   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy