Results 141 to 150 of about 2,520,258 (203)

Rh(II)/Pd(0) Dual Catalysis: Carbenoid N-H Insertion/Allylation Cascade Reaction to Construct Highly Functionalized and Polysubstituted Pyrrolidines. [PDF]

Molecules
Tang M, Jiao X, He D, Zhao JX, Liu P, Li CT.   +5 more
europepmc   +1 more source

Neferine inhibits BMECs pyroptosis and maintains blood-brain barrier integrity in ischemic stroke by triggering a cascade reaction of PGC-1α. [PDF]

Sci Rep
Zheng ZJ, Zhu LZ, Qiu H, Zheng WY, You PT, Chen SH, Hu CL, Huang JR, Zhou YJ.   +8 more
europepmc   +1 more source

Nano oxygen chamber by cascade reaction for hypoxia mitigation and reactive oxygen species scavenging in wound healing. [PDF]

Bioact Mater
Han X, Ju L, Saengow C, Ren W, Ewoldt R, Fan T, Irudayaraj J.   +6 more
europepmc   +1 more source

Phosphomethylpyrimidine Synthase (ThiC): Trapping of Five Intermediates Provides Mechanistic Insights on a Complex Radical Cascade Reaction in Thiamin Biosynthesis. [PDF]

ACS Cent Sci
Sharma V, Fedoseyenko D, Joshi S, Abdelwahed S, Begley TP.   +4 more
europepmc   +1 more source

Enantioselective synthesis of spiro[indoline-3,1'-pyrazolo[1,2-<i>b</i>]phthalazine] derivatives <i>via</i> an organocatalytic three-component cascade reaction. [PDF]

RSC Adv
Song L, Sun Y, An R, Wang L, Jin Y.
europepmc   +1 more source

A Facile Ugi/Ullmann Cascade Reaction to Access Fused Indazolo-Quinoxaline Derivatives with Potent Anticancer Activity. [PDF]

Molecules
Li Y, He L, Qin H, Liu Y, Yang B, Xu Z, Yang D.   +6 more
europepmc   +1 more source

Synthesis of novel aryl-substituted 2-aminopyridine derivatives by the cascade reaction of 1,1-enediamines with vinamidinium salts to develop novel anti-Alzheimer agents. [PDF]

Sci Rep
Loori S, Pourtaher H, Mehranpour A, Hasaninejad A, Eftekharian M, Iraji A.   +5 more
europepmc   +1 more source

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Bounds on the Ultrasensitivity of Biochemical Reaction Cascades

Bulletin of Mathematical Biology, 2023
Abstract The ultrasensitivity of a dose response function can be quantifiably defined using the generalized Hill coefficient of the function. Our group examined an upper bound for the Hill coefficient of the composition of two functions, namely the product of their individual Hill coefficients.
Marcello Pajoh-Casco, Abishek Vinujudson, German Enciso   +2 more
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Cluster Channeling in Cascade Reactions

The Journal of Physical Chemistry B, 2021
Enzymatic cascade reactions, where a substrate is converted into a product in several steps, play a critical role in many biological systems. The enzymes in such reactions are often clustered inside intracellular compartments. To understand the effect of localization, we develop a theory for cascade reactions converting substrates into intermediates ...
openaire   +2 more sources

Cascade Reactions in Total Synthesis

Angewandte Chemie International Edition, 2006
AbstractThe design and implementation of cascade reactions is a challenging facet of organic chemistry, yet one that can impart striking novelty, elegance, and efficiency to synthetic strategies. The application of cascade reactions to natural products synthesis represents a particularly demanding task, but the results can be both stunning and ...
K C, Nicolaou, David J, Edmonds, Paul G, Bulger   +2 more
openaire   +2 more sources