Results 61 to 70 of about 1,385,457 (289)

Experimental Investigation of Gain Offset Behavior of Feedforward-Controlled WDM AGC EDFA Under Various Dynamic Wavelength Allocations

open access: yesIEEE Photonics Journal, 2016
Realizing dynamics in the optical layer is becoming more important for efficient optical communication networks such as protection switching in the optical domain or reconfiguring the optical layer to meet traffic fluctuations.
Kiyo Ishii, Junya Kurumida, Shu Namiki
doaj   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

open access: yesFEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan   +11 more
wiley   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

open access: yesFEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Time-varying channel estimation in reconfigurable intelligent surface assisted communication system

open access: yesTongxin xuebao
Aiming at the key problems need to be solved, such as cascade channel sparse representation, time-varying channel parameter tracking and signal reconstruction, for time-varying cascade channels estimation of reconfigurable intelligent surface (RIS ...
Kai SHAO, Ben LU, Guangyu WANG
doaj   +2 more sources

All-optical signal processing using cascaded quadratic interactions in periodically poled lithium niobate waveguides

open access: yes, 2012
This thesis investigates all-optical signal processing using cascaded quadratic nonlinearities in periodically poled lithium niobate (PPLN) waveguides for telecommunication applications.
Liu, Sheng
core   +1 more source

Beta1 subunits enable fentanyl‐induced BK channel activation and opioid regulation of cerebral artery diameter

open access: yesFEBS Open Bio, EarlyView.
During the current opioid crisis, the majority of overdose deaths are attributed to ultra‐potent synthetic opioids, such as fentanyl. While fentanyl exerts its action via opioid receptors, we propose that potassium channels in the brain blood vessels may also sense fentanyl.
Shiwani Thapa   +4 more
wiley   +1 more source

Flat-Top Eight-Channel Wavelength Division Demultiplexer for L-Band Optical Communication With Low Crosstalk

open access: yesIEEE Photonics Journal
We have demonstrated an eight-channel wavelength demultiplexer in the L-band based on a cascaded Mach-Zehnder interferometer (MZI) lattice filter fabricated on an 8-inch silicon nitride (SiN) photonics platform.
Yilin Zhong   +5 more
doaj   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit   +11 more
wiley   +1 more source

Diabetes‐Associated Cognitive Impairment: Pathophysiology and Emerging Therapies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Diabetes‐associated cognitive impairment (DACI) is a common yet underrecognized condition, manifesting along a spectrum from mild cognitive impairment to dementia. DACI encompasses patients who develop vascular dementia (VaD) or Alzheimer's disease (AD) with diabetes as a risk factor; however, in certain patients, particularly those lacking ...
Osman Corbali   +4 more
wiley   +1 more source

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