Our study employed a modified tissue‐clearing method combined with deep imaging for 3D reconstruction of ovarian endometriosis (OEM) lesions, revealing its morphological polymorphism at tissue and cellular levels. Besides, vessels preferentially clustered around the ectopic epithelium, with their distribution pattern strongly linked to the location of ...
Fanyuan Sun +13 more
wiley +1 more source
Epigenetic editing of the STAT5B promoter attenuates milk nutrient loss in a bovine mastitis cell model. [PDF]
Li S +5 more
europepmc +1 more source
Mechanistic Insights into Glycine's Regulation of Milk Protein Synthesis via PI3K-AKT-mTOR Signaling. [PDF]
Zhang X +12 more
europepmc +1 more source
A guide to the types, structures, and multifaceted functions of matrix metalloproteinases in cancer
Matrix metalloproteinases (MMPs) orchestrate cancer progression and metastasis through proteolytic and non‐proteolytic actions. By remodeling the tumor microenvironment, enhancing growth factor availability, and modulating cell behavior, MMPs promote proliferation, migration or invasion, and epithelial‐to‐mesenchymal transition. Alongside extracellular
Zoi Piperigkou +4 more
wiley +1 more source
Pickering emulsion as an oral delivery platform of anti-TNF-α antibody for ulcerative colitis therapy. [PDF]
Xie J +6 more
europepmc +1 more source
Kinetics of casein micelle destabilization
Destabilization of casein micelles in reconstituted skim milk was studied experimentally in both nonmixed and mixed conditions. The process of micelle destabilization was described with a three-step kinetic model accounting for hydrolysis of casein in ...
Sefcikova, M, Sefcik, J, Bales, V
core
S‐Adenosylmethionine (SAM) hydrolases counter increased SAM epimerisation in thermophilic archaea
S‐Adenosyl‐l‐methionine (SAM) is a vital enzyme cofactor. Epimerisation at the sulfonium centre of biologically active (SS,SCα)‐SAM is driven by heat, yielding biologically inactive (RS,SCα)‐SAM. Here, two novel archaeal SAM hydrolases from the thermophilic Sulfolobus acidocaldarius and the halophilic Haloferax volcanii are shown to cleave (RS,SCα)‐SAM.
Agnes Bartels +7 more
wiley +1 more source
Casein genotypes associate with baseline and dynamic regression components of seminal quality in Murciano-Granadina bucks. [PDF]
Peláez Caro M +5 more
europepmc +1 more source
Dissociation of casein micelles to soluble casein complexes [PDF]
R F, Murphy, W K, Downey, R D, Kearney
openaire +2 more sources
Okur‐Chung neurodevelopmental syndrome (OCNDS) is a neurodevelopmental disorder associated with mutations in the gene coding for Protein kinase CK2α. In this work, 42 variants of CK2α associated with OCNDS were characterized in vitro. This included determination of catalytic activity and CK2α/CK2β‐interaction as well as an assessment of evolutionary ...
Alexander Gast +3 more
wiley +1 more source

