Results 161 to 170 of about 135,908 (286)

Three‐Dimensional Architecture of Ectopic Epithelium and Vasculature in Ovarian Endometriosis Revealed by Tissue‐Clearing Imaging

open access: yesCell Proliferation, EarlyView.
Our study employed a modified tissue‐clearing method combined with deep imaging for 3D reconstruction of ovarian endometriosis (OEM) lesions, revealing its morphological polymorphism at tissue and cellular levels. Besides, vessels preferentially clustered around the ectopic epithelium, with their distribution pattern strongly linked to the location of ...
Fanyuan Sun   +13 more
wiley   +1 more source

Mechanistic Insights into Glycine's Regulation of Milk Protein Synthesis via PI3K-AKT-mTOR Signaling. [PDF]

open access: yesCurr Issues Mol Biol
Zhang X   +12 more
europepmc   +1 more source

A guide to the types, structures, and multifaceted functions of matrix metalloproteinases in cancer

open access: yesThe FEBS Journal, EarlyView.
Matrix metalloproteinases (MMPs) orchestrate cancer progression and metastasis through proteolytic and non‐proteolytic actions. By remodeling the tumor microenvironment, enhancing growth factor availability, and modulating cell behavior, MMPs promote proliferation, migration or invasion, and epithelial‐to‐mesenchymal transition. Alongside extracellular
Zoi Piperigkou   +4 more
wiley   +1 more source

Pickering emulsion as an oral delivery platform of anti-TNF-α antibody for ulcerative colitis therapy. [PDF]

open access: yesInt J Pharm
Xie J   +6 more
europepmc   +1 more source

Kinetics of casein micelle destabilization

open access: yes, 2000
Destabilization of casein micelles in reconstituted skim milk was studied experimentally in both nonmixed and mixed conditions. The process of micelle destabilization was described with a three-step kinetic model accounting for hydrolysis of casein in ...
Sefcikova, M, Sefcik, J, Bales, V
core  

S‐Adenosylmethionine (SAM) hydrolases counter increased SAM epimerisation in thermophilic archaea

open access: yesThe FEBS Journal, EarlyView.
S‐Adenosyl‐l‐methionine (SAM) is a vital enzyme cofactor. Epimerisation at the sulfonium centre of biologically active (SS,SCα)‐SAM is driven by heat, yielding biologically inactive (RS,SCα)‐SAM. Here, two novel archaeal SAM hydrolases from the thermophilic Sulfolobus acidocaldarius and the halophilic Haloferax volcanii are shown to cleave (RS,SCα)‐SAM.
Agnes Bartels   +7 more
wiley   +1 more source

Casein genotypes associate with baseline and dynamic regression components of seminal quality in Murciano-Granadina bucks. [PDF]

open access: yesSci Rep
Peláez Caro M   +5 more
europepmc   +1 more source

Functional characterization of 42 CK2α de novo variants associated with Okur‐Chung neurodevelopmental syndrome

open access: yesThe FEBS Journal, EarlyView.
Okur‐Chung neurodevelopmental syndrome (OCNDS) is a neurodevelopmental disorder associated with mutations in the gene coding for Protein kinase CK2α. In this work, 42 variants of CK2α associated with OCNDS were characterized in vitro. This included determination of catalytic activity and CK2α/CK2β‐interaction as well as an assessment of evolutionary ...
Alexander Gast   +3 more
wiley   +1 more source

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