Results 51 to 60 of about 149,645 (257)

α‐Synuclein Forms Distinct Micelle‐Like Assemblies at Low Ionic Strengths

Advanced Science, EarlyView.
At high ionic strength, α‐synuclein forms diverse assemblies, including oligomers, fibrils, and condensates. Here, we show that at low ionic strength, α‐synuclein adopts a distinct, low‐abundance assembly state. These assemblies maintain a constant size above a critical concentration and do not coalesce, suggesting a micelle‐like organization ...
Sophie Hertel, Soumik Ray, Federica Saraceno, Giacomo Nisini, Georgia Nasi, Thomas Oliver Mason, Antonin Kunka, Effrosyni Agrimaki, Dannie Juul Olesen, Francesco Simone Ruggeri, Alexander K. Buell   +10 more
wiley   +1 more source

Structure and Function of a Multi‐Megadalton Virus‐Like Proteolytic Dodecahedron

Angewandte Chemie, EarlyView.
Zuzalysin, a virulence metallopeptidase of the periodontal pathogen Porphyromonas gingivalis, is secreted as a latent, flexible ≈95‐kDa monomer. Calcium triggers cysteine‐switch activation and hierarchical assembly into pentamers, bipentamers, tripentamers, and a ≈5.6‐MDa, ≈355‐Å dodecahedron. Structures at 1.8–3.6 Å reveal a virus‐sized catalytic cage
Mariusz Madej, Arturo Rodríguez‐Banqueri, Danuta Mizgalska, Borys Szmigielski, Zuzanna Nowakowska, Małgorzata Benedyk‐Machaczka, Monika Bzowska, Katarzyna Mikruta, Juan Sebastián Ramírez‐Larrota, Chinanu Agunanne, Olivier Julien, Anthony J. O'Donoghue, Carsten Scavenius, Mario López‐Martín, Enrique Marcos, Łukasz Koziej, Sebastian Glatt, Pablo Guerra, Ulrich Eckhard, Jan Potempa, F. Xavier Gomis‐Rüth   +20 more
wiley   +2 more sources

Application of FT near spectroscopy for determination of true protein and casein in milk

Czech Journal of Animal Science, 2007
Our study deals with a possibility of determining true protein and casein in cow's, ewe's and goat's milk and in ewe's colostrums by FT NIR spectroscopy. Samples of milk were analysed by FT NIR in the reflectance mode with the transflectance cuvette. The
K. Šustová, J. Růžičková, J. Kuchtík   +2 more
doaj   +1 more source

Genetic analysis of protein composition of bovine milk [PDF]

, 2010
This thesis is part of the Dutch Milk Genomics Initiative, and the general aim was to obtain more insight into the genetic background of bovine milk protein composition.
Schopen, G.C.B.
core  

Implications of kappa-casein evolutionary diversity for the self-assembly and aggregation of casein micelles

, 2019
<p>Code for the analysis and figures for the paper: “Implications of kappa-casein evolutionary diversity for the self-assembly and stabilization of casein micelles” (in preparation)</p ...
Jean Manguy, Jean Manguy (3594356)
core   +1 more source

Genetic variability of the equine casein genes. [PDF]

, 2016
The casein genes are known to be highly variable in typical dairy species, such as cattle and goat, but the knowledge about equine casein genes is limited.
Thaller, G, Tetens, J, Jagannathan, Vidhya, Drögemüller, Cord, Rieder, S, Leeb, Tosso, Brinkmann, J   +6 more
core   +1 more source

An Effector TaCRVP From Tuta Absoluta Oral Secretion Impairs H2O2‐Mediated Plant Defense by Targeting Tomato SlCAT2

Advanced Science, EarlyView.
The Tuta absoluta salivary effector TaCRVP subverts tomato immunity by hijacking host catalase SlCAT2. Through a sophisticated dual mechanism, TaCRVP simultaneously promotes SlCAT2 tetramerization for activation and blocks its SlAdBiL‐mediated degradation for stabilization.
Jianquan Yan, Youdan Zhang, Zhujun Wang, Huatao Tang, Huiping Liu, Zi Chen, Shuai Liu, Jiayi Shi, Lu Peng, Youming Hou   +9 more
wiley   +1 more source

Code for the analysis and figures for the paper: "Implications of kappa-casein evolutionary diversity for the self-assembly and stabilization of casein micelles"

, 2019
Code for the analysis and figures for the paper: "Implications of kappa-casein evolutionary diversity for the self-assembly and stabilization of casein micelles"
Denis C. Shields (18564), Jean Manguy, Denis C. Shields, Jean Manguy (3594356)   +3 more
core   +1 more source

A novel splicing variant encoding putative catalytic alpha subunit of maize protein kinase CK2 [PDF]

, 2009
A cDNA highly homologous to the known catalytic alpha subunit of protein kinase CK2 was cloned from maize (Zea mays). It was designated ZmCK2 alpha-4 (accession no. AAF76187). Sequence analysis shows that ZmCK2 alpha-4 and the previously identified ZmCK2
Moro, S, Jadwiga Szczegielniak, Giorgio Cozza, Łebska, Maja, Grażyna Dobrowolska, Stefano Moro, Grażyna Muszyńska, Dobrowolska, Grażyna, Cozza, G, Szczegielniak, Jadwiga, Maja Łebska, Muszyńska, Grażyna   +11 more
core   +1 more source

Macrophage RSAD2 Couples mtDNA Synthesis With a Self‐Amplifying Inflammatory Circuit to Orchestrate Tissue Repair

Advanced Science, EarlyView.
Macrophage RSAD2 dually regulates CMPK2—the rate‐limiting enzyme for mitochondrial DNA synthesis—by suppressing its ubiquitination and promoting its phosphorylation via Csnk2a2 recruitment. This amplifies mtDNA production, which simultaneously activates a cGAS‐STING‐IRF3‐RSAD2 feedforward loop and the NLRP3 inflammasome, driving a self‐sustaining ...
Haomiao Yuan, Shukui Du, Chunfei Li, Xinjie Li, Shuyang Mu, Anran Qu, Hengxu Yan, Chongchong Xu, Jinnong Yang, Jingkai Sun, Yijun Wang, Jiayang Xiao, Fuyuan Zhang, Linlin Wang, Tiegang Li, Rui Zhao, Dawei Guan   +16 more
wiley   +1 more source