Results 141 to 150 of about 43,522 (228)

Computational Study of Coumarin Compounds as Potential Inhibitors of Casein Kinase 2: DFT, 2D-QSAR, ADMET and Molecular Docking Investigations

Casein kinase 2 (CK2) is an ubiquitous, essential, and highly pleiotropic protein kinase whose abnormally high constitutive activity is suspected to underlie its pathogenic potential in neoplasia and other diseases.
Belaidi, Salah, Ouassaf, Mebarka, Prasad, Onkar, Sinha, Leena, Chtita, Samir, Serdaroglu, Goncaguel, Chennai, Hind Yassmine   +6 more
core   +1 more source

Polycation-dependent, Ca2+-antagonized phosphorylation of calmodulin by casein kinase-2 and a spleen tyrosine protein kinase.

, 1987
Ten distinct protein kinases have been tested for their ability to phosphorylate calmodulin. Only casein kinase-2 and a spleen tyrosine protein kinase (TPK-III) proved effective, their phosphorylation efficiency being dramatically enhanced by histones ...
PINNA, LORENZO, Lorenzo A. Pinna, MEGGIO, FLAVIO, BRUNATI, ANNA MARIA, Pinna, Lorenzo A., Flavio Meggio, Anna Maria Brunati   +6 more
core   +1 more source

Quaternary Structure of Casein Kinase 2 [PDF]

Journal of Biological Chemistry, 1995
Emmanuelle Valero, Salvatore De Bonis, Odile Filhol, Richard H. Wade, Joerg Langowski, Edmond M. Chambaz, Claude Cochet   +6 more
openaire   +1 more source

Casein Kinase 2 (CK2): A Possible Therapeutic Target in Acute Myeloid Leukemia. [PDF]

Cancers (Basel), 2023
Bruserud Ø, Reikvam H.
europepmc   +1 more source

Data from: Prion protein inhibits fast axonal transport through a mechanism involving casein kinase 2

, 2017
Prion diseases include a number of progressive neuropathies involving conformational changes in cellular prion protein (PrPc) that may be fatal sporadic, familial or infectious.
Song, Yuyu, Zamponi, Emiliano, Cataldi, Gabriel E., Caicedo, Hector H., Helguera, Pablo R., Brady, Scott T., Buratti, Fiamma A., Ma, Jiyan, Pigino, Gustavo F., Bisbal, Mariano, Lorenzo, Alfredo, Morfini, Gerardo A., Caicedo, Hector Hugo, Jungbauer, Lisa M., LaDu, Mary J.   +14 more
core   +1 more source

Casein Kinase 2 [PDF]

, 2020
openaire   +1 more source

Casein kinase 2 is the major enzyme in brain that phosphorylates Ser129 of human alpha-synuclein: Implication for alpha-synucleinopathies.

, 2007
In Lewy body diseases and multiple system atrophy, alpha-synuclein is hyperphosphorylated at Ser129, suggesting a role in pathogenesis. Here, we report purification of the protein kinase in rat brain that phosphorylates Ser129 and its identification as ...
Arai, T, Mann, DMA, Nonaka, T, Hasegawa, M, Saito, T, Taniguchi, S, Iwatsubo, T, Goedert, M, Ishii, A, Hisanaga, S   +9 more
core   +1 more source

Casein Kinase 2 Alpha Inhibition Protects against Sepsis-Induced Acute Kidney Injury. [PDF]

Int J Mol Sci, 2023
Koo JH, Yu HC, Nam S, Kim DC, Lee JH.
europepmc   +1 more source

Disruption in the regulation of casein kinase 2 in circadian rhythm leads to pathological states: cancer, diabetes and neurodegenerative disorders. [PDF]

Front Mol Neurosci, 2023
Malik MZ, Dashti M, Fatima Y, Channanath A, John SE, Singh RKB, Al-Mulla F, Thanaraj TA.   +7 more
europepmc   +1 more source

Exploring the potential of approved drugs for triple-negative breast cancer treatment by targeting casein kinase 2: Insights from computational studies. [PDF]

PLoS One, 2023
Shoaib TH, Ibraheem W, Abdelrahman M, Osman W, Sherif AE, Ashour A, Ibrahim SRM, Ghazawi KF, Miski SF, Almadani SA, ALsiyud DF, Mohamed GA, Alzain AA.   +12 more
europepmc   +1 more source