Editorial: Casein kinases in human diseases [PDF]
Frontiers in Molecular Biosciences, 2022 Andrea Venerando +2 more
exaly +8 more sources
Casein kinases are required for the stability of the glucose-sensing receptor Rgt2 in yeast [PDF]
Scientific Reports, 2022 In yeast, glucose induction of HXT (glucose transporter gene) expression is achieved via the Rgt2 and Snf3 glucose sensing receptor (GSR)-mediated signal transduction pathway.
Jeong-Ho Kim +6 more
doaj +2 more sources
Heterologous Caseins: The Role of Phosphorylation in Their Functionality and How to Achieve It [PDF]
BiomoleculesHeterologous expression of caseins in non-mammalian systems offers a sustainable and scalable alternative for producing milk proteins, with potential applications in the food and biopharmaceutical industries.
Soledad Mora Vásquez +3 more
doaj +2 more sources
Casein Kinases 2-dependent phosphorylation of the placental ligand VAR2CSA regulates Plasmodium falciparum-infected erythrocytes cytoadhesion. [PDF]
PLoS PathogensPlacental malaria is characterized by the massive accumulation and sequestration of infected erythrocytes in the placental intervillous blood spaces, causing severe birth outcomes.
Dominique Dorin-Semblat +7 more
doaj +2 more sources
Phosphorylation of Shiftless by casein kinase 1 δ/ε is required for its antiviral activity [PDF]
Journal of VirologyShiftless (SHFL) is a host antiviral factor that inhibits the viral −1 programmed ribosomal frameshifting (−1PRF). How the antiviral activity of SHFL is regulated is not known. Here, we report that the phosphorylation of SHFL by the casein kinase 1 delta
Yongle Wang +3 more
doaj +2 more sources
Molecular genetic characterization of CASEIN KINASE 1-LIKE 12 in Arabidopsis [PDF]
Plant Signaling & BehaviorThe CASEIN KINASE 1 (CK1) family plays diverse roles in the development, physiology, and disease in eukaryotes. In Arabidopsis thaliana, the CASEIN KINASE 1-LIKE (CKL) family has 13 members, but to date, the roles of these kinases remain largely unclear.
Adam Seluzicki +3 more
doaj +2 more sources
Phosphorylation of αs2‐casein by two rat liver ‘casein kinases’ [PDF]
FEBS Letters, 1978 MEGGIO, FLAVIO +2 more
openaire +3 more sources
CK2 and protein kinases of the CK1 superfamily as targets for neurodegenerative disorders
Frontiers in Molecular Biosciences, 2022 Casein kinases are involved in a variety of signaling pathways, and also in inflammation, cancer, and neurological diseases. Therefore, they are regarded as potential therapeutic targets for drug design.
Andrea Baier, Ryszard Szyszka
doaj +1 more source
Ribofuranosyl‐benzimidazole derivatives as inhibitors of casein kinase‐2 and casein kinase‐1 [PDF]
European Journal of Biochemistry, 1990 5,6‐Dichloro‐1‐(β‐d‐ribofuranosyl)benzimidazole (DiCl‐RB) is a powerful inhibitor of casein kinase‐2 (CK‐2) [Zandomeni, R. et al. (1986) J. Biol. Chem. 261, 3414–3420]. Here a series of 17 analogues of DiCl‐RB has been employed for studying the specificity and the mode of action of this family of CK‐2 inhibitors.
MEGGIO, FLAVIO, Shugar D, PINNA, LORENZO
openaire +3 more sources
PLoS Neglected Tropical Diseases, 2021 The unicellular protozoan Trypanosoma cruzi is the causing agent of Chagas disease which affects several millions of people around the world. The components of the cell signaling pathways in this parasite have not been well studied yet, although its ...
Edio Maldonado +3 more
doaj +1 more source