Results 21 to 30 of about 24,797 (285)
Phosphorylation of the chromatin binding domain of KSHV LANA. [PDF]
PLoS Pathogens, 2012 The Kaposi sarcoma associated herpesvirus (KSHV) latency associated nuclear antigen (LANA) is expressed in all KSHV associated malignancies and is essential for maintenance of KSHV genomes in infected cells.
Crystal Woodard +12 more
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Heliyon, 2019 Phosphorylation of proteins on serine/threonine residues represents an important biochemical mechanism to regulate several cellular processes. Polo-like kinases (PLKs) are a family of serine-threonine kinases that play an imminent role in cell cycle ...
Sujata Chauhan +5 more
doaj +1 more source
Anticancer Alkaloid Lamellarins Inhibit Protein Kinases
Marine Drugs, 2008 Lamellarins, a family of hexacyclic pyrrole alkaloids originally isolated from marine invertebrates, display promising anti-tumor activity. They induce apoptotic cell death through multi-target mechanisms, including inhibition of topoisomerase I ...
Laurent Meijer +8 more
doaj +1 more source
Dangerous Duplicity: The Dual Functions of Casein Kinase 1 in Parasite Biology and Host Subversion
Frontiers in Cellular and Infection Microbiology, 2021 Casein Kinase 1 (CK1) family members are serine/threonine protein kinases that are involved in many biological processes and highly conserved in eukaryotes from protozoan to humans.
Najma Rachidi +2 more
doaj +1 more source
Phosphorylation of protein kinase C by casein kinase‐1 [PDF]
FEBS Letters, 1989 Because phosphorylation of protein kinase C (PKC) may provide a mechanism for regulation of this enzyme, we have examined the ability of two other kinases to phosphorylate PKC. Our results show that casein kinase 1 (CK‐1), but not casein kinase 2 (CK‐2), can phosphorylate PKC in the absence of Ca2+ and phospholipids.
Vila, Jordi +4 more
openaire +2 more sources
Memorias do Instituto Oswaldo Cruz, 2004 Trypanosoma evansi contains protein kinases capable of phosphorylating endogenous substrates with apparent molecular masses in the range between 20 and 205 kDa.
José Manuel Galán-Caridad +4 more
doaj +1 more source
Roscovitine-Derived, Dual-Specificity Inhibitors of Cyclin-Dependent Kinases and Casein Kinases 1.
, 2008 Cyclin-dependent kinases (CDKs) and casein kinases 1 (CK1) are involved in the two key molecular features of Alzheimer's disease, production of amyloid-beta peptides (extracellular plaques) and hyper-phosphorylation of Tau (intracellular neurofibrillary ...
Myrianthopoulos, Vassilios +11 more
core +2 more sources
Identity and substrate specificity of human erythrocyte membrane-bound and cytosolic casein kinases
, 1991 The relationship and substrate specificity of the human erythrocyte membrane kinase and casein kinase A were investigated. Based onStaphylococcus aureus V8 protease digestion patterns, the 2 kinases appeared to be structurally homologous.
Tao, Mariano, Wei, Tiequan
core +2 more sources
Site-specific phosphorylation of casein kinase 1 δ (CK1δ) regulates its activity towards the circadian regulator PER2. [PDF]
PLoS ONE, 2017 Circadian rhythms are intrinsic ~24 hour cycles that regulate diverse aspects of physiology, and in turn are regulated by interactions with the external environment.
Gracie Wee Ling Eng +2 more
doaj +1 more source
Casein kinase 2 is essential for mitophagy [PDF]
The EMBO Reports, 2013 Mitophagy is a process that selectively degrades mitochondria. When mitophagy is induced in yeast, the mitochondrial outer membrane protein Atg32 is phosphorylated, interacts with the adaptor protein Atg11 and is recruited into the vacuole with mitochondria.
Tomotake, Kanki +10 more
openaire +2 more sources