Results 31 to 40 of about 147 (74)

Design and Synthesis of Novel Candidate CK1δ Proteolysis Targeting Chimeras (PROTACs). [PDF]

Molecules
Arnold M, Thompson T, Glennie L, Hollnagel M, Sapkota G, Peifer C.   +5 more
europepmc   +1 more source

CK1α, CK1δ, and CK1ε are necrosome components which phosphorylate serine 227 of human RIPK3 to activate necroptosis. [PDF]

Proc Natl Acad Sci U S A, 2020
Hanna-Addams S, Liu S, Liu H, Chen S, Wang Z.   +4 more
europepmc   +1 more source

CK1δ/ε-mediated TDP-43 phosphorylation contributes to early motor neuron disease toxicity in amyotrophic lateral sclerosis. [PDF]

Acta Neuropathol Commun
Ko VI, Ong K, Kwon DY, Li X, Pietrasiewicz A, Harvey JS, Lulla M, Bhat G, Cleveland DW, Ravits JM.   +9 more
europepmc   +1 more source

Exosomes derived from hucMSC attenuate renal fibrosis through CK1δ/β-TRCP-mediated YAP degradation. [PDF]

Cell Death Dis, 2020
Ji C, Zhang J, Zhu Y, Shi H, Yin S, Sun F, Wang Q, Zhang L, Yan Y, Zhang X, Xu W, Qian H.   +11 more
europepmc   +1 more source

Molecular simulations of enzymatic phosphorylation of disordered proteins and their condensates. [PDF]

Nat Commun
Zippo E, Dormann D, Speck T, Stelzl LS.
europepmc   +1 more source

Evaluation of QT Liability for PF-05251749 in the Presence of Potential Circadian Rhythm Modification. [PDF]

CPT Pharmacometrics Syst Pharmacol, 2020
Huh Y, Chen D, Riley S, Chang C, Nicholas T.   +4 more
europepmc   +1 more source

Pharmacological targeting of casein kinase 1δ suppresses oncogenic NRAS-driven melanoma. [PDF]

Nat Commun
Wen Y, Wang H, Yang X, Zhu Y, Li M, Ma X, Huang L, Wan R, Zhang C, Li S, Jia H, Guo Q, Lu X, Li Z, Shen X, Zhang Q, Si L, Yin C, Liu T.   +18 more
europepmc   +1 more source

Autokinase Activity of Casein Kinase 1 δ/ε Governs the Period of Mammalian Circadian Rhythms. [PDF]

J Biol Rhythms, 2019
Guo G, Wang K, Hu SS, Tian T, Liu P, Mori T, Chen P, Johnson CH, Qin X.   +8 more
europepmc   +1 more source

Motor neuron preservation and decrease of in vivo TDP-43 phosphorylation by protein CK-1δ kinase inhibitor treatment. [PDF]

Sci Rep, 2020
Martínez-González L, Rodríguez-Cueto C, Cabezudo D, Bartolomé F, Andrés-Benito P, Ferrer I, Gil C, Martín-Requero Á, Fernández-Ruiz J, Martínez A, de Lago E.   +10 more
europepmc   +1 more source

Effects of a selective casein kinase 1δ and ε inhibitor on FcεRI expression and IgE-mediated immediate-type cutaneous reactions in dogs. [PDF]

J Vet Med Sci, 2019
Ohno H, Takahashi K, Yanuma N, Ogawa M, Hasegawa A, Sugita K, Kawano K, Sasaki K, Shirai J, Nagaoka K, Ohmori K.   +10 more
europepmc   +1 more source