Results 171 to 180 of about 318,537 (297)

Artemisinin attenuated ischemic stroke induced pyroptosis by inhibiting ROS/TXNIP/NLRP3/Caspase-1 signaling pathway

Yue Wang, Huiling Yuan, Da Shen, Shuyuan Liu, Weiao Kong, Keying Zheng, Jiehong Yang, Lijun Ge   +7 more
openalex   +1 more source

PLA2G16‐Mediated Tetracosatetraenoic Acid Rewires Fatty Acid Oxidation to Impair CD8+ T Cell Immune Function in Promoting Breast Cancer Lung Metastasis

Advanced Science, EarlyView.
Illustrating how tumor‐derived PLA2G16 regulates tetracosatetraenoic acid (C24:4 (n‐6)) accumulation and CD8+ T cell activation via the C24:4‐PPARα‐FAO axis in early metastatic niches, thereby promoting lung metastasis of triple‐negative breast cancer.
Yubi Gan, Die Meng, Lei Lang, Jing Luo, Peijin Dai, Chao Chang, Zexiu Lu, Yuetong Guo, Rui Wang, Shanchun Chen, Xi Tang, Yixuan Hou, Dongmei Tan, Manran Liu   +13 more
wiley   +1 more source

Curcumin exerts therapeutic effects on colorectal cancer by inducing pyroptosis through caspase‑1 activation. [PDF]

Mol Med Rep
Zhu J, Yang L, Fang Z, Chen J, Wu Y, Liu H, Liu S, Fei B.   +7 more
europepmc   +1 more source

Induction of ASC pyroptosis requires gasdermin D or caspase-1/11-dependent mediators and IFNβ from pyroptotic macrophages [PDF]

, 2020
Cuiping Zhang, Caiqi Zhao, Xiaohong Chen, Rujia Tao, Sijiao Wang, Guangxun Meng, Xing Liu, Changzhou Shao, Xiao Su   +8 more
openalex   +1 more source

Alkyltriphenylphosphonium Binding to Cardiolipin Triggers Oncosis in Cancer Cells

Advanced Science, EarlyView.
Alkyltriphenylphosphonium, exemplified by TPP+‐C14, preferentially accumulates in mitochondria and selectively binds to cardiolipin, a key phospholipid of the inner mitochondrial membrane, causing loss of mitochondrial membrane potential, severe cellular ATP depletion, and calcium imbalance.
Jin Li, Hang Zheng, Yuxing Lin, Ziwei Zhao, Yijia Mai, Zhangrong Lou, Qiang Liu, Zhao Ma, Chengjun Wu   +8 more
wiley   +1 more source

Novel strategies for PEDV to interfere with host antiviral immunity through Caspase-1. [PDF]

Virulence
Shi W, Xu W, Lv Q, Zhang Z, Fu X, Li D, He S, Wang Y, Xu J, Liu S, Ge Y, Li P, Ou C, Li X, Shi F.   +14 more
europepmc   +1 more source

YopJ-Induced Caspase-1 Activation in Yersinia-Infected Macrophages: Independent of Apoptosis, Linked to Necrosis, Dispensable for Innate Host Defense

, 2012
Ying Zheng, Sarit Lilo, Patricio Mena, James B. Bliska   +3 more
openalex   +2 more sources

Precise Regulation of Membrane Proteins: From Physical Technology to Biomolecular Strategy

Advanced Science, EarlyView.
This review summarizes the emerging strategies for the precise regulation of membrane proteins using physical stimuli and biomolecule‐based tools. These methods provide new insights into cell regulation and offer promising directions for future disease treatment.
Xiu Zhao, Qingqing Zhou, Mengli Li, Wen Zou, Zhenzhong Zhang, Jinjin Shi, Junjie Liu   +6 more
wiley   +1 more source

The omega-3 DHA induces pyroptosis and mitochondrial dysfunction in ovarian cancer cells via ROS and caspase-1 activation. [PDF]

Cell Death Discov
Pasquarelli-do-Nascimento G, Bezerra SP, Manchine JP, Lago NCS, Braz-de-Melo HA, Soares da Cruz N, Bellozi PMQ, Rocha AP, Santos IO, Lago FG, Machado SA, Nicola AM, de Bem AF, Báo SN, Magalhães KG.   +14 more
europepmc   +1 more source

Anti-apoptotic Activity of Ginsenoside Rb₁in Hydrogen Peroxide-treated Chondrocytes: Stabilization of Mitochondria and the Inhibition of Caspase-3 [PDF]

, 2012
Ji-Young Na, Sokho Kim, Kibbeum Song, Kyu-Hee Lim, Gee-Wook Shin, Jong‐Hoon Kim, Bumseok Kim, Young‐Bae Kwon, Jungkee Kwon   +8 more
openalex   +1 more source