Results 251 to 260 of about 341,145 (337)

Caspase-mediated Cleavage of Hematopoietic Progenitor Kinase 1 (HPK1) Converts an Activator of NFκB into an Inhibitor of NFκB [PDF]

, 2001
Ruediger Arnold, Jen Liou, Hannes C. A. Drexler, Arthur Weiss, Friedemann Kiefer   +4 more
openalex   +1 more source

Snord15b Maintains Stemness of Intestinal Stem Cells via Enhancement of Alternative Splicing of Btrc Short Isoform for Suppression of β‐Catenin Ubiquitination

Advanced Science, EarlyView.
In intestinal stem cells (ISCs), Snord15b associates with Ilf2 to recruit splicing factors for alternative splicing of Btrc mRNA, leading to the generation of short Btrc. This short Btrc fails to form a functional E3 ubiquitin ligase complex for β‐catenin ubiquitination and degradation.
Yuwei Xu, Peikang Zhang, Zhen Xiong, Yufei Lan, Hui Guo, Runyuan Wu, Cunzhen Li, Hongzhe Fan, Ying Du, Xiaoxiao Zhu, Dongdong Fan, Zhonglong Wang, Yong Tian, Zusen Fan   +13 more
wiley   +1 more source

miR-126-5p protects from URSA via inhibiting Caspase-1-dependent pyroptosis of trophoblast cells. [PDF]

Cell Mol Life Sci
Zhu X, Xu K, Ai S, Zhang Y, Chu C, Wei R, Gao S, Liu L, Li W, Zhang Y, Kikete S, Liu X, Zhang Z, Li X.   +13 more
europepmc   +1 more source

Differential Expression of Apoptotic Protease-Activating Factor-1 and Caspase-3 Genes and Susceptibility to Apoptosis during Brain Development and after Traumatic Brain Injury [PDF]

, 2001
Alexander G. Yakovlev, Katsuya Ota, Geping Wang, Vilen Movsesyan, Weili Bao, Koichiro Yoshihara, Alan I. Faden   +6 more
openalex   +1 more source

Draper‐ATG3 Interaction Positively Regulates Autophagy to Mediate Silk Gland Degradation in Bombyx mori

Advanced Science, EarlyView.
Draper is evolutionarily conserved across most insect species. Loss of Draper inhibits autophagy activation, delaying middle silk gland degradation in the silkworm during metamorphosis. Draper interacts with autophagy ‐ related protein 3 (ATG3) to orchestrate autophagosome formation—a process essential for silk gland degradation during the larval‐pupal
Shiyu Zou, Yuhan Luo, Yue Jin, Wenhui Jing, Yuxin Huang, Yanting Liang, Yinghui Li, Zhihua Hao, Yusong Xu, Huabing Wang   +9 more
wiley   +1 more source

The islet-resident macrophage is in an inflammatory state and senses microbial products in blood [PDF]

, 2017
Aggarwal, Amit, Amit, Anders, Andrade, Banaei-Bouchareb, Boris Calderon, Buxadé, Calderon, Calderon, Calderon, Carrero, Castellino, Chee, Chen, Chevrier, Christen, del Rey, Diana, Diana, Dinarello, Dobin, Droop, Dror, Dufour, Emil R. Unanue, Ewald, Ferris, Foster, Fridovich, García, Gautier, Gilchrist, Greeley, Griffith, Haldar, Harrow, Heng, Javier A. Carrero, Johnson, Kaikkonen, Kanehisa, Kawai, Kim, Koblansky, Kotas, Kurth, Kägi, Lavin, Litvak, Love, Mandrup-Poulsen, Markle, Matloubian, Maxim N. Artyomov, Melli, Mi, Mi, Miller, Mootha, Moratz, Oldenburg, Pakala, Park, Pasparakis, Pavel N. Zakharov, Reddy, Reif, Ritchie, Rütti, Schott, Smyth, Stephen T. Ferris, Subramanian, Suri, Tai, Terauchi, Thomas, Vomund, Wen, Wood, Wu, Xiaoxiao Wan, Yamada, Yang, Yosef, Yosef, Yurkovetskiy, Zhao   +88 more
core   +2 more sources

(-)-Epigallocatechin Gallate Ameliorates Chronic Stress-Induced Depression-Like Behavior in Rats by Inhibiting the NF-κB/Caspase-1 Signaling Pathway and Reducing IL-1β and IL-18 Expression. [PDF]

Food Sci Nutr
Wu G, Xu J, Wu W, Jin J, Li S, Huang Y, Zhang Z, Hu Y, Zhang Y, Liu Y, Xu Y, Zheng M, Xu C, Lu W, Wu H, Hu L.   +15 more
europepmc   +1 more source

Differential Effects of Caspase-1/Interleukin-1β–Converting Enzyme on Acinar Cell Necrosis and Apoptosis in Severe Acute Experimental Pancreatitis [PDF]

, 2001
Bettina Rau, Adam S. Paszkowski, Susanne Lillich, Katja Baumgart, Peter Möller, H. G. Beger   +5 more
openalex   +1 more source

A Serum‐Stable Antimicrobial Peptide‐Based Delivery Platform for Selective Treatment of Nontargetable and Chemoresistant Tumors

Advanced Science, EarlyView.
A modular antimicrobial‐peptide‐based therapeutic system integrating membrane‐targeted selectivity, a conformation‐driven polyethylene glycolylated blocker, and serum‐stabilizing N‐cap is developed. The optimized conjugate 270 shows potent, rapid killing of the desired tumor cells, high serum stability, low off‐target toxicity, and broad applicability,
Tianxing Liu, Lingyu Ke, Ruize Sun, Xiaoling Chen, Mei Zhou, Olaf R. P. Bininda‐Emond, Chengbang Ma, Yangyang Jiang, Tao Wang, Chris Shaw, Lei Wang, Tianbao Chen, Alideertu Dong   +12 more
wiley   +1 more source

Bromodomain protein 4 inhibitor JQ-1 alleviates hepatic ischemia-reperfusion injury by blocking the NLRP3/caspase-1 pathway. [PDF]

World J Emerg Med
Wang L, Gong W.
europepmc   +1 more source