Results 261 to 270 of about 16,739,924 (339)

αB-crystallin enhances radioresistance in basal-like breast cancer cells by suppressing caspase-3 activation. [PDF]

Sci Prog
Yuan Y, Zhang X, Xu Y, Ge Y, Wu A.
europepmc   +1 more source

Caspase‐3 Modulates Regenerative Response After Stroke

Stem Cells, 2014
Wenying Fan, Yiqin Dai, Haochen Xu, Ximin Zhu, Ping Cai, Lixiang Wang, Chungang Sun, Changlong Hu, P. Zheng, Bing-Qiao Zhao   +9 more
semanticscholar   +1 more source

Mitochondrial Dysfunction Increases Expression of Endothelin-1 and Induces Apoptosis through Caspase-3 Activation in Rat Cardiomyocytes In Vitro

, 2000
Koichi Yuki, Takashi Miyauchi, Yoshihiko Kakinuma, Nobuyuki Murakoshi, Takahiko Suzuki, Junichi Hayashi, Katsutoshi Goto, Iwao Yamaguchi   +7 more
openalex   +1 more source

Nanocatalytic Neuroprotection and Neurological Recovery Post‐Traumatic Brain Injury

Advanced Science, EarlyView.
This study demonstrates that combining Ce0.7Zr0.3O2 nanozymes with nimodipine enhances neuroprotection after traumatic brain injury. The therapy reduces oxidative stress, neuronal apoptosis, and improves blood–brain barrier integrity, with nanozymes effective at low doses.
Xinjie Hong, Liang Zhao, Xianzheng Sang, Chao Ma, Meiqi Chang, Xinran Song, Wei Feng, Tao Xu, Li Ding, Yu Chen, Lijun Hou   +10 more
wiley   +1 more source

Role of RGS17 in cisplatin-induced cochlear inflammation and ototoxicity via caspase-3 activation. [PDF]

Front Immunol
Al Aameri RFH, Alanisi EMA, Al Sallami D, Alberts I, Tischkau S, Rybak LP, Ramkumar V.   +6 more
europepmc   +1 more source

Engineering Neutrophil Vesicles for Synergistic Protection against Ischemia/Reperfusion Injury after Lung Transplant

Advanced Science, EarlyView.
Engineered neutrophil‐derived vesicles (SOD2‐Fer‐1@CVs) co‐delivering antioxidant and ferroptosis‐inhibitory agents enable inflammation‐targeted, ROS‐responsive therapy for ischemia–reperfusion injury in lung transplantation. Synergizing with ex vivo lung perfusion, this strategy alleviates oxidative stress and inflammation, restores vascular integrity,
Hao‐Xiang Yuan, Yu‐Yun Ye, Pu Shen, Jie Zhang, Qian‐Fang Meng, Ying Chen, Xin Xu, Xuan‐Lin Zhang, Lang Rao, Zhi‐Jin Fan, Jian‐Xing He   +10 more
wiley   +1 more source

Caerin 1.1 and 1.9 peptides induce acute caspase 3/GSDME-mediated pyroptosis in epithelial cancer cells. [PDF]

Sci Rep
Luo Y, Li J, Fu Q, Zhang P, Song X, Liu M, Mo R, Fu J, Tang S, Wu J, Yang X, Liu X, Wang T, Ni G.   +13 more
europepmc   +1 more source

Vinburnine Sensitizes Radiotherapy Efficacy in Nasopharyngeal Carcinoma by Triggering Pyroptosis and Immune Responses via Activation of EDAR‐NFκB Pathway

Advanced Science, EarlyView.
This study demonstrates that vinburnine, an approved cerebrovascular drug, synergizes with radiotherapy in nasopharyngeal carcinoma (NPC) by modulating EDAR‐NFκB signaling through directly binding to EDAR, leading to triggering apoptosis/pyroptosis, and amplifying CCL5/CX3CL1‐driven T‐cell cytotoxicity.
Jing Chen, Nian Liu, Qian Tao, Jie Wu, Jinyu Huang, Can Lu, Qiuqiu Li, Liangfang Shen, Xiang Chen, Cong Peng   +9 more
wiley   +1 more source

Prognostic Significance of DNAJB4 Expression in Gastric Cancer: Correlation with CD31, Caspase-3, and Tumor Progression. [PDF]

Diagnostics (Basel)
Cheng CY, Chen YL, Ho H, Huang CY, Chu SE, Liang YJ.   +5 more
europepmc   +1 more source

Disruption of NF‐κB‐Mediated Copper Homeostasis Sensitizes Breast Cancer to Cuproptosis

Advanced Science, EarlyView.
This study reveals a feedback mechanism regulating copper homeostasis, in which copper directly interacts with TAK1 to activate NF‐κB signaling, while NF‐κB transcriptionally suppresses copper transporter (CTR1) expression. These findings highlight a promising therapeutic strategy for breast cancer by combining NF‐κB inhibitors with copper chelators or
Xiaomei Zhang, Yaqing Su, Weixiong Yang, Zimin Song, Zicheng Sun, Xueji Wu, Jianwen Chen, Bing Gao, Zekang Wang, Lei Wang, Qiwei Jiang, Lang Bu, Jingting Li, Ying Lin, Wei Xie, Jie Li, Jianping Guo   +16 more
wiley   +1 more source