Results 281 to 290 of about 16,739,924 (339)

Licorice extract and carbenoxolone protect PC12 cells against serum/glucose deprivation-induced apoptosis through modulation of caspase-3 and PARP activation. [PDF]

Avicenna J Phytomed
Hosseinzadeh H, Ramazani E, Bakhshi S, Tayarani-Najaran Z.   +3 more
europepmc   +1 more source

CDH1 Orchestrates Anabolic Events to Promote Cell Cycle Initiation

Advanced Science, EarlyView.
Cell proliferation requires the integration of cell cycle and anabolic signals. G1‐phase regulator CDH1 coordinates anabolism through the CDH1‐VHL‐AARS2/HIF1α axis, while CDH1‐accumulated R5P is sensed by TKTL1 to facilitate CDH1 degradation and cell cycle initiation, constituting a CDH1‐centered regulatory circuit.
Yun‐Zi Mao, Jiao‐Jiao Zhang, Meng‐Qi You, Han Wang, Yan Lin, Yuan Fang, Hui‐Lu Zhang, Yuan‐Yuan Qu, Qian Zhou, Meng Wang, Gang Li, Zi‐Fan Guo, Meng Xu, Jie Liu, Peng‐Cheng Lin, Yi‐Yuan Yuan, Yu Kang, Shi‐Min Zhao, Wei Xu   +18 more
wiley   +1 more source

Evaluation of Titanium Particles, TNF-α, and Caspase-3 Concentrations in Patients with Bones Fixations of the Maxilla and Mandibule. [PDF]

Int J Mol Sci
Antonowicz B, Mierzejewska ŻA, Borys J, Maciejczyk M, Prokopiuk S, Car H.   +5 more
europepmc   +1 more source

Engineering Bacteria as Living Therapeutics in Cancer Therapy

Advanced Science, EarlyView.
Through synthetic biology approaches, natural bacteria can be genetically programmed into multifunctional living therapeutics. These engineered bacteria are capable of secreting anti‐tumor factors, displaying tumor‐associated antigens on their surface, or undergoing programmed self‐lysis to release therapeutic cargo.
Jiangfeng Chen, Jiaqi Chen, Yixuan Chen, Wenxuan Yuan, Jiao Zhang, Guoqing Wang, Zhuojun Dai   +6 more
wiley   +1 more source

Survivin and caspase-3 and PanIN. Disorders of apoptosis in the process of pancreatic cancer formation

Studia Medyczne
Konrad Zaręba, Justyna Dorf, Kerianne Cummings, Anna Pryczynicz, Katarzyna Guzińska-Ustymowicz, Bogusław Kędra   +5 more
doaj   +1 more source

Caspase 3/GSDME-Mediated Corneal Epithelial Pyroptosis Promotes Dry Eye Disease. [PDF]

Invest Ophthalmol Vis Sci
Wang L, Tian Y, Zhang H, Dong Y, Hua X, Yuan X.   +5 more
europepmc   +1 more source

Microglia Drive Peripapillary Vascular Density Reduction in Normal Tension Glaucoma by Regulating the Rpl17/Stat5b/Apoa1 Axis

Advanced Science, EarlyView.
This study revealed that E50K mutant microglia drive retinal peripapillary vascular density reduction in NTG via the Rpl17/Stat5b/Apoa1 axis and identified Apoa1 as a novel suppressor of retinal vascular endothelial cells. These findings identify a potential therapeutic target for glaucoma and support the clinical potential of EA for protecting RGCs ...
Di Zhang, Sisi Chen, Yanfeng Zhang, Leyi Qiu, Mengxian Du, Wulian Song, Fengyi Guo, Jingyang Zhang, Xinna Liu, Huiping Yuan   +9 more
wiley   +1 more source

Alternative Models for Anticancer Drug Discovery From Natural Products Using Binary Tumor‐Microenvironment‐on‐a‐Chip

Advanced Science, EarlyView.
This study presents a binary tumor‐microenvironment‐on‐a‐chip (T‐MOC) system incorporating multicellular tumor spheroids (MCTs) as an alternative preclinical platform to evaluate the efficacy of anticancer natural products. The T‐MOC model reproduces in vivo drug delivery barriers and physiological conditions, enabling morphological analysis to predict
Youngwon Kim, Si Hyeon Chae, Dahae Lee, Bum Soo Lee, Jiseok Lim, Hyo‐Il Jung, Ki Hyun Kim, Bongseop Kwak   +7 more
wiley   +1 more source

[Retracted] Curcumin improves the paclitaxel-induced apoptosis of HPV-positive human cervical cancer cells via the NF-κB-p53-caspase-3 pathway. [PDF]

Exp Ther Med
Dang YP, Yuan XY, Tian R, Li DG, Liu W.
europepmc   +1 more source