Results 301 to 310 of about 476,553 (353)

Survivin and caspase-3 and PanIN. Disorders of apoptosis in the process of pancreatic cancer formation

Studia Medyczne
Konrad Zaręba, Justyna Dorf, Kerianne Cummings, Anna Pryczynicz, Katarzyna Guzińska-Ustymowicz, Bogusław Kędra   +5 more
doaj   +1 more source

Research progress on biomarkers of traumatic brain injury

Animal Models and Experimental Medicine, EarlyView.
Traumatic brain injury: From primary insult to secondary neuroinflammation and degeneration. Abstract Traumatic brain injury (TBI) is a common disorder of the nervous system and has become a leading cause of death and disability worldwide, imposing a substantial burden on patients and their social circles. Its main symptoms include dyskinesia, language
Xuting Shen, Si Cheng, Shuyi Chen, Mengyue Wang, Tangying Li, Weicheng Xu, Yifan Zhang, Ping Yuan, Lei Shi   +8 more
wiley   +1 more source

Alpha-1 Antitrypsin Mediates Spontaneous Resolution of Acute Gouty Inflammation Via Inhibiting Caspase 3/GSDME-dependent Macrophage Pyroptosis. [PDF]

Inflammation
Li X, Liu L, Tong S, Wang F, Zhu L, Cheng Q, Zhang P, Chen M, Xie Y, Wang L, Yu H, Wu H.   +11 more
europepmc   +1 more source

Caspase-8, association with Alzheimer\u27s disease and functional analysis of rare variants [PDF]

, 2017
Cruchaga, Carlos, et al.,, Lord, Jenny
core   +1 more source

Cancer therapy‐induced ototoxicity: Current challenges and emerging management strategies

Animal Models and Experimental Medicine, EarlyView.
This review comprehensively examines the key risk factors for cancer therapy‐induced ototoxicity, including cumulative drug dose, genetic susceptibility, and combined treatment regimens. It highlights current challenges in ototoxicity monitoring, such as insufficient timeliness and limited clinical adoption, and advocates for standardized auditory ...
Yuqi Huang, Baoying Xu, Xinru Chen, Yu Chen, Dehong Yu   +4 more
wiley   +1 more source

Caspase-3 in Brain Death Donors Is Associated with Reduced Primary Graft Dysfunction After Heart Transplantation. [PDF]

Int J Mol Sci
Herrador L, González-Costello J, Niubo-Bosch J, Calatayud-Samper L, Maestro-Benedicto A, Farrero-Torres M, Blasco-Peiro T, Almenar-Bonet L, Blázquez-Bermejo Z, Garrido-Bravo I, Gran-Ipiña F, Grande-Trillo A, Manito N, Moreno-Gonzalez G.   +13 more
europepmc   +1 more source

Astrocytic Mitochondria Transplantation Rescues Neuron Loss and Dendritic Injuries in Acute Cerebral Ischemic Stroke Mouse Model by Flexibly Regulating Mitochondria Dynamics

Annals of Neurology, EarlyView.
Objective Cerebral ischemic stroke causes neuronal oxygen/energy deprivation, disrupting mitochondrial function including reduced membrane potential and bioenergetics, exacerbating neuronal injury. Mitochondrial defects are, therefore, a central neuropathological node and potential therapeutic target.
Ning Bian, Jianing Shen, Linwei Tian, Jinghui Li, Lu Yang, Bo Yuan, Shulin Li, Yuyu Niu, Lu Zhao, Jingkuan Wei   +9 more
wiley   +1 more source

CDC5L binds to ELAVL1 to inhibit pyroptosis in hepatocellular carcinoma through the Caspase 3/GSDME signaling pathway. [PDF]

Int J Mol Med
Liang S, Zhu Z, Tang Y, Zhou S, Xiao M, Gong X, Ye K.   +6 more
europepmc   +1 more source

Predominance of Ferroptotic Cell Death Mechanisms in Substantia Nigra Neurodegeneration in Parkinson's Disease

Annals of Neurology, EarlyView.
Objective The extent of neuronal loss in Parkinson's disease (PD) and the pathogenic processes underlying neuronal dysfunction and loss remain poorly understood. Here, we analyzed the expression of key molecules representing different cell death signaling pathways and their association with Lewy pathology, dopaminergic (DA) neuron loss and stage of PD ...
Yue Jing Heng, Anusha Jayaraman, Richard Reynolds, Jia Nee Foo   +3 more
wiley   +1 more source