Results 311 to 320 of about 476,553 (353)

Vitexin induces apoptosis and enhances daunorubicin efficacy in acute leukemia via modulation of the HIF-1α/Bcl-2/caspase-3 pathway. [PDF]

Sci Rep
Jirawatpraphakorn C, Tanyong D, Jaree A, Owattanapanich W.   +3 more
europepmc   +1 more source

Investigation of the Effect of Borago officinalis on Bax/Bcl-2/Caspase-3 Pathways Against Spleen Toxicity Induced by Lead Acetate in Rats

Samet Tekin, Furkan Aykurt, Burak Çınar, Ömer Yardımcı, Burak Batuhan Lacın, Merve Bolat, İsmail Bolat, Ali Cınar   +7 more
openalex   +2 more sources

Natural compound triptolide induces caspase-3/GSDME-mediated pyroptosis by promoting ROS accumulation in small cell lung cancer. [PDF]

Cancer Cell Int
Yan Y, Xu Z, Wang C, Liu Y, Long Y, Yuan X, Chu Q.   +6 more
europepmc   +1 more source

Activation of human endogenous retroviruses by Sox proteins induces cell apoptosis via the caspase-3 pathway. [PDF]

Front Microbiol
Hossain MJ, Monde N, Sasaki H, Nyame P, Amesimeku WAO, Terasawa H, Matsumura S, Matsui T, Tsutsuki H, Maeda Y, Sawa T, Monde K.   +11 more
europepmc   +1 more source

Cleavage of CAD by caspase-3 determines the cancer cell fate during chemotherapy. [PDF]

Nat Commun
Ma J, Zhao J, Zhang C, Tan J, Cheng A, Niu Z, Lin Z, Pan G, Chen C, Ding Y, Zhong M, Zhuang Y, Xiong Y, Zhou H, Zhou S, Xu M, Ye W, Li F, Song Y, Wang Z, Hong X.   +20 more
europepmc   +1 more source

Protection against post-resuscitation renal injury by Artesunate via inhibition of caspase-3/Gasdermin E -mediated pyroptosis. [PDF]

Resusc Plus
Wang Q, Shen P, Wu W, Zhu J, Xu J.
europepmc   +1 more source

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Caspase-3 Activators as Anticancer Agents

Current Protein & Peptide Science, 2023
Background: The cancer is still a major cause of death worldwide. Among different targets to design anticancer agents, caspase-3 is an important target as its cleavage and activation lead to apoptosis and finally, cancer cell death. Apart from some naturally occurring molecules, many small molecules have been reported as caspase-3 activators ...
Nitin Srivastava, Anil Kumar Saxena
openaire   +2 more sources