Results 191 to 200 of about 6,024,904 (336)

Optogenetic induction of caspase-8 mediated apoptosis by employing Arabidopsis cryptochrome 2. [PDF]

Sci Rep, 2023
Mo W, Su S, Shang R, Yang L, Zhao X, Wu C, Yang Z, Zhang H, Wu L, Liu Y, He Y, Zhang R, Zuo Z.   +12 more
europepmc   +1 more source

Expression of caspases-3, -6 and -8 and their relation to apoptosis in non-small cell lung carcinoma [PDF]

, 2001
Ulla T�rm�nen-N�p�nkangas, Ylermi Soini, Katriina Kahlos, Vuokko L. Kinnula, Paavo P��kk�   +4 more
openalex   +1 more source

NAD+‐Boosters Improve Mitochondria Quality Control In Parkinson's Disease Models Via Mitochondrial UPR

Advanced Science, EarlyView.
Treatment of MPTP‐incubated cells with NAD+‐boosters increase the UPRmt/mitophagy‐related mitochondria quality control (MQC). Disturbed plasma UPRmt‐mitophagy‐mediated MQC profiles in PD patient samples. NMN inhibits motor deficit and forestalls neuropathology phenotypes of PD mice, which is required the atf4‐medicated UPRmt pathway.
Shuoting Zhou, Xi Xiong, Jialong Hou, Qi Duan, Yi Zheng, Tao Jiang, Jiani Huang, Haijun He, Jiaxue Xu, Keke Chen, Wenwen Wang, Jinlai Cai, Jingjing Qian, Huijun Chen, Weihong Song, XinShi Wang, Chenglong Xie   +16 more
wiley   +1 more source

Caspase-8 and Tyrosine Kinases: A Dangerous Liaison in Cancer. [PDF]

Cancers (Basel), 2023
Contadini C, Ferri A, Cirotti C, Stupack D, Barilà D.   +4 more
europepmc   +1 more source

Extended polyglutamine selectively interacts with caspase-8 and -10 in nuclear aggregates [PDF]

, 2001
M U, Toshiyuki Miyashita, Y Ohtsuka, Yuko Okamura-Oho, Yoshiaki Shikama, Masao Yamada   +5 more
openalex   +1 more source

Caspase-8 activation

Reactome - a curated knowledgebase of biological pathways, 2013
openaire   +1 more source

Glucose Deprivation‐Induced Disulfidptosis via the SLC7A11‐INF2 Axis: Pan‐Cancer Prognostic Exploration and Therapeutic Validation

Advanced Science, EarlyView.
Glucose deprivation or GLUT1 inhibition induces disulfidptosis in SLC7A11high ovarian cancer cells by promoting cystine accumulation, NADPH/ATP depletion, and F‐actin disulfide formation. SLC7A11 interacts with INF2 to further increase H₂O₂ levels and impair mitochondrial fission, suppressing cell migration. Targeting the SLC7A11–INF2 axis represents a
Zhenyu Song, Qiuming Yao, Lina Huang, Dan Cui, Jun Xie, Leilei Wu, Jianfeng Huang, Bo Zhai, Dan Liu, Xiao Xu   +9 more
wiley   +1 more source

RAD51 modulates in nasopharyngeal carcinoma cells by regulating Caspase-8-mediated pyroptosis. [PDF]

Discov Oncol
Xie F, Song J, Tian Y, Zhang X, Chen T, Xu M.   +5 more
europepmc   +1 more source

Caspase 8 Activity in Membrane Blebs After Anti-Fas Ligation [PDF]

, 2001
Beverly Z. Packard, Akira Komoriya, Tilmann M. Brotz, Pierre A. Henkart   +3 more
openalex   +1 more source

NOX2 Contributes to High‐Frequency Outer Hair Cell Vulnerability in the Cochlea

Advanced Science, EarlyView.
This study first identifies NOX2 as a differentially expressed gene related to oxidative damage in the apical and basal turns through single‐cell RNA sequencing. NOX2 gene knockout mitigates OHCs damage caused by neomycin and noise and enhances Nrf2 expression and nuclear translocation.
Meihao Qi, Zejun Gao, Yang Qiu, Renfeng Wang, Keyong Tian, Bo Yue, Xinyu Zhang, Peng Zhang, Ziqi Wu, Qingwen Zhu, Zhenzhen Liu, Zhuoyao Ma, Xueying Zhou, Yu Han, Jun Chen, Jianhua Qiu, DingJun Zha   +16 more
wiley   +1 more source