Results 271 to 280 of about 6,024,904 (336)

TRIF-TAK1 signaling suppresses caspase-8/3-mediated GSDMD/E activation and pyroptosis in influenza A virus-infected airway epithelial cells. [PDF]

iScience
Sun Y, Yu H, Zhan Z, Liu W, Liu P, Sun J, Zhang P, Wang X, Liu X, Xu X.   +9 more
europepmc   +1 more source

Transforming growth factor beta-induced apoptosis in primary murine hepatocytes is caspase-8 dependent

, 2001
Charles M. Samson, Patty A. Lange, Mark A. Bird, Melissa A. Hayden, David A. Brenner, Kevin E. Behms   +5 more
openalex   +1 more source

Post‐Translational Modified Neoantigens in Autoimmune Diseases: Challenges of Immune Tolerance

Advanced Science, EarlyView.
Autoimmune diseases have a high incidence and disability rate. The pathogenesis of autoimmune diseases involves the interaction among genetic factors, environmental factors, and immune disorders. The post‐translational modified neoantigens are the key nodal of these three factors. And these post‐translational modified neoantigens, after being presented
Yue Zhai, Kefei Wu, Qi Lin, Zhenzhen Cao, Yankun Jia, Ping Zhu   +5 more
wiley   +1 more source

PARP inhibitors enhance antitumor immune responses by triggering pyroptosis via TNF-caspase 8-GSDMD/E axis in ovarian cancer. [PDF]

J Immunother Cancer
Xia Y, Huang P, Qian YY, Wang Z, Jin N, Li X, Pan W, Wang SY, Jin P, Drokow EK, Li X, Zhang Q, Zhang Z, Li P, Fang Y, Yang XP, Han Z, Gao QL.   +17 more
europepmc   +1 more source

CONVERSION FROM A TYPE I TO A TYPE II DEATH RECEPTOR-MEDIATED PATHWAY THROUGH A PARTIAL INHIBITION OF CASPASE-8

, 2001
Bryan W. Johnson, Enriqué Cepero, Lawrence Boise   +2 more
openalex   +1 more source

Peptide‐Based Biomaterials as a Promising Tool for Cancer Radiotherapy

Advanced Science, EarlyView.
This review provides a systematic overview of peptide‐based biomaterials in tumor radiotherapy, covering their roles as both radiosensitizers and radiopharmaceuticals. Peptide‐based radiosensitizers are generally divided into three categories: peptides as direct radiosensitizers, peptides as carriers of radiosensitizers, and targeted‐peptide‐modified ...
Qian Wang, Xinhui Chu, Jianfeng Liu
wiley   +1 more source

Retraction: MicroRNA-21 Inhibits the Apoptosis of Osteosarcoma Cell Line SAOS-2 via Targeting Caspase 8. [PDF]

Oncol Res
Oncology Research Editorial Office.
europepmc   +1 more source

Novel ATR/PARP1 Dual Inhibitors Demonstrate Synergistic Antitumor Efficacy in Triple‐Negative Breast Cancer Models

Advanced Science, EarlyView.
Novel ATR/PARP1 dual inhibitors are developed for the first time. Advanced lead B8 effectively reduces cell viability in vitro and suppresses tumor growth in vivo, with better potency than ATRi and PARPi alone or in combination. Mechanistically, B8 induces apoptosis, arrests the cell cycle, and inhibits cancer cells colony formation, migration, and ...
Yuan Gao, Jiawei Zhou, Chen‐Chen Wang, Zong‐Hao Wang, Nian‐Dong Mao, Meng‐Lan He, Peng‐Peng Zhang, Ping Huang, Guo‐Wei Ye, Yu‐Qing Zhang, Feng‐Hui Tang, Hang Zhang, Tian Xie, Xiang‐Yang Ye   +13 more
wiley   +1 more source

Arginine methylation of caspase-8 controls life/death decisions in extrinsic apoptotic networks. [PDF]

Oncogene
Wohlfromm F, Ivanisenko NV, Pietkiewicz S, König C, Seyrek K, Kähne T, Lavrik IN.   +6 more
europepmc   +1 more source

Dopamine D1 Receptor Contributes to Glucocorticoid‐Associated Osteonecrosis of Femoral Head Protection Through the ATF3/CHOP Axis to Inhibit Osteoblastic Apoptosis

Advanced Science, EarlyView.
This work identifies a novel mechanism by which dopamine D1 receptor (DRD1) contributes to the pathogenesis of glucocorticoid (GC)‐associated osteonecrosis of the femoral head (ONFH) through the regulation of osteoblastic apoptosis, indicating that DRD1 serves as a critical mediator of the crosstalk between the nervous and skeletal systems.
Kai Zheng, Wenming Li, Tianhao Wang, Gaoran Ge, Wei Zhang, Yi Qin, Wenhao Li, Zebin Wu, Zhen Wang, Gang Rui, Yaozeng Xu, Dechun Geng   +11 more
wiley   +1 more source