Genome-wide association studies identify the role of caspase-9 in kidney disease. [PDF]
Doke T +9 more
europepmc +1 more source
Caspase-8 and Apaf-1-independent Caspase-9 Activation in Sendai Virus-infected Cells [PDF]
Michael Bitzer +11 more
openalex +1 more source
Advanced Microfluidics for Single Cell‐Based Cancer Research
Cutting‐edge microfluidic platforms are transforming single‐cell cancer research. This review highlights advanced technologies, from droplet microfluidics to tumour‐chips, that enable functional and spatial single‐cell analyses. By integrating biosensing, immune components, and patient‐derived materials, these systems offer new insights into tumour ...
Adriana Carneiro +10 more
wiley +1 more source
Helminthic larval stage induces cellular apoptosis via caspase 9-mediated mitochondrial dysfunction. [PDF]
Sternkopf LE +15 more
europepmc +1 more source
Asiaticoside Increases Caspase-9 Activity in MCF-7 Cells and Inhibits TNF-α and IL-6 Expression in Nude Mouse Xenografts via the NF-κB Pathway. [PDF]
Al-Saeedi FJ.
europepmc +1 more source
Antiapoptotic Activity of the Free Caspase Recruitment Domain of Procaspase-9 [PDF]
Anastasis Stephanou +3 more
openalex +1 more source
Osteoblast‐CD4+ CTL Crosstalk Mediated by SIRT1/DAAM2 Axis Prevents Age‐Related Bone Loss
In the osteoblastic niche, SIRT1 activates and recruits CD4+ CTLs by increasing DAAM2 expression via EZH2 deacetylation and boosting the secretion of key chemokines, such as CCL3, CCL5, and CXCL10. Then, CD4+ CTL directly eliminates senescent osteoblasts in an MHC‐II‐dependent way, thereby slowing down the process of bone ageing and effectively ...
Bin Yang +20 more
wiley +1 more source
Caspase 9-induced apoptosis enables efficient fetal cell ablation and disease modeling. [PDF]
Matsui K +18 more
europepmc +1 more source

