Results 161 to 170 of about 294,590 (260)

[Retracted] Paeoniflorin inhibits nucleus pulposus cell apoptosis by regulating the expression of Bcl-2 family proteins and caspase-9 in a rabbit model of intervertebral disc degeneration. [PDF]

Exp Ther Med
Shi L, Teng H, Zhu M, Li C, Huang K, Chen B, Dai Y, Wang J.   +7 more
europepmc   +1 more source

Plk1 Regulates Caspase-9 Phosphorylation at Ser-196 and Apoptosis of Human Airway Smooth Muscle Cells. [PDF]

Am J Respir Cell Mol Biol, 2022
Liao G, Wang R, Tang DD.
europepmc   +1 more source

MAM‐Localized MANF Counteracts Microinflammatory Stress to Attenuate Mitochondrial Dysfunction and Cataractogenesis in High Myopia

Advanced Science, EarlyView.
Chronic microinflammation in high myopia suppresses MANF in lens epithelial cells. MANF normally resides within MAMs and promotes ubiquitin‐mediated degradation of the ER Ca2+ pump SERCA2. MANF loss causes pathological SERCA2 accumulation, MAM hyperassembly, and disrupted ER‐to‐mitochondria Ca2+ transfer, leading to mitochondrial failure, oxidative ...
Xin Liu, Hao Li, Ching Kang, Dongling Guo, Shuyu Liu, Jiaqi Meng, Zhiqian Huang, Yu Du, Xiangjia Zhu   +8 more
wiley   +1 more source

Rhodiola crenulata induces apoptosis in bone metastatic breast cancer cells via activation of caspase-9 and downregulation of MtMP activity. [PDF]

Sci Rep
Ravi P, Jasuja H, Sarkar D, Vahidi Pashaki B, Gaikwad HK, Vahidi Pashaki P, Katti DR, Shetty K, Katti KS.   +8 more
europepmc   +1 more source

Asiaticoside Increases Caspase-9 Activity in MCF-7 Cells and Inhibits TNF-α and IL-6 Expression in Nude Mouse Xenografts via the NF-κB Pathway. [PDF]

Molecules, 2023
Al-Saeedi FJ.
europepmc   +1 more source

A Plant Photoregulator‐Inspired S‐Type Heterojunction System for Diabetic Keratopathy via Tri‐Modal Light‐Driven Immunometabolic Reprogramming, Tissue Repair, and Antibacterial Activity

Advanced Science, EarlyView.
To address the multifaceted imbalance in diabetic keratopathy, a light‐responsive biomimetic platform (WCNx‐Rh2) is developed and integrates glucose degradation, immune modulation, and antibacterial defense through a designed heterojunction and screened immunomodulator. WCNx‐Rh2 reduces AGEs/ROS and inflammatory signaling, reprogramming dendritic cells
Mengzhen Zhao, Zhibin Zhou, Yuxuan Wei, Xiangfan Huang, Zhiyong Zhou, Jiaheng Chen, Haoxin Cheng, Xiaotian Hu, Xiaolei Wang   +8 more
wiley   +1 more source

Stem bark ethanolic extract of <i>Pinus merkusii</i> induces caspase 9-mediated apoptosis in HeLa cells. [PDF]

Open Vet J
Achmad AB, Proboningrat A, Ansori ANM, Fadholly A, Rochmi SE, Samsudin RR, Hidayatik N, Hendarti GA, Jayanti S.   +8 more
europepmc   +1 more source

Evolutionarily Ancient Caspase-9 Sensitizes Immune Effector Coelomocytes to Cadmium-Induced Cell Death in the Sea Cucumber, <i>Holothuria leucospilota</i>. [PDF]

Front Immunol, 2022
Li X, Chen T, Wu X, Li Z, Zhang X, Jiang X, Luo P, Hu C, Wong NK, Ren C.   +9 more
europepmc   +1 more source

Targeting NSUN2‐Mediated m5C Modification Attenuates Chondrocyte Senescence and NLRP3 Activation in Osteoarthritis

Advanced Science, EarlyView.
NSUN2‐mediated m5C modification cooperates with ALYREF to stabilize and export IP3R3 mRNA, increasing IP3R3 expression and Ca2 + overload in chondrocytes. This signaling promotes mitochondrial dysfunction, NLRP3 inflammasome activation, and senescence, thereby accelerating osteoarthritis progression.
Guping Mao, Wei Li, Zhencan Lin, Zengfa Deng, Ming Li, Zongrui Jiang, Changzhao Li, Dianbo Long, Yan Kang   +8 more
wiley   +1 more source

Association Aamong Ppolymorphisms in the Aapoptosis-Rrelated NKX3-1, Caspase-3, Caspase-9, and BCL-2 Genes and Prostate Cancer Susceptibility From 9706 Cases and 12,567 Controls. [PDF]

Cancer Rep (Hoboken)
Feng Y, Feng Z, Li D, Gui J, Song Z, Xie X, Zhu L, Mi Y.   +7 more
europepmc   +1 more source