Results 141 to 150 of about 4,575,594 (299)

Nitric oxide and thioredoxin modulate the activity of caspase 9 in HepG2 cells. [PDF]

open access: yesBiochim Biophys Acta Gen Subj, 2023
Chakraborty S   +6 more
europepmc   +1 more source

Photomicrographs depicting immunohistochemical staining of caspase-9.

open access: yes, 2013
For immunohistochemical analyses, brown colour indicates specific immunostaining of caspase-9 and light blue colour indicates nuclear haematoxylin staining.
Sarwat Sultana (38191)   +7 more
core   +1 more source

The Host Cell Factor Phosphatase‐2A Subunit PR130 Restricts Replication of Herpes Simplex Virus Type‐1

open access: yesAdvanced Science, EarlyView.
Molecular, genetic, virological, and biochemical analysis in combination with global proteome and phosphoproteome profiling and functional assays were applied to study the role of PR130 in the context of HSV‐1 replication. The observations reveal that host‐intrinsic mechanisms regulate HSV‐1 replication and highlight PR130 as a susceptibility factor of
Johannes Jungwirth   +10 more
wiley   +1 more source

Apoptosis triggered redistribution of caspase-9 from cytoplasm to mitochondria

open access: yes, 2003
Caspase-9 is an apoptosis initiator protease activated as a response to the mitochondrial damage in the cytoplasmic complex apoptosome. By fluorescence labelling of proteins, confocal microscopy and subcellular fractionations we demonstrate that caspase ...
Stenovec, M   +9 more
core   +1 more source

A Computational Strategy for Identifying Self‐Assembling Food‐Derived Molecules for Antiparasitic Nanotherapy

open access: yesAdvanced Science, EarlyView.
An integrated computational screening strategy identified ursolic acid (UA) and 18β‐glycyrrhetinic acid (18βGA) as a self‐assembling food‐derived molecular pair. The resulting carrier‐free nanoparticles (UA‐18βGA) showed synergistic antiparasitic activity, reduced combined toxicity, and host‐protective anti‐inflammatory effects in zebrafish and murine ...
Shenye Qu   +8 more
wiley   +1 more source

Исследование содержания белков-маркеров апоптоза в пульпе временных и постоянных зубов при воспалении

open access: yesЭндодонтия Today, 2020
In the present job the maintenance annexin V, caspase-9 and the tumour necrosis factor-α in gomogenates pulps time and second teeth in norm has been investigated and at an inflammation.

doaj  

The Dimeric Caspase-9 Can No Longer Be Activated the Same Way as the WT Caspase-9

open access: yes, 2013
(A) Increasing amounts of Apaf-1 (residues 1–570) led to a corresponding increase in the catalytic activity of the WT caspase-9, but had no effect on the activity of the dimeric caspase-9.
Eric N Shiozaki (68540)   +5 more
core   +1 more source

Bioorthogonal Fluorogenic Reporters for Noninvasive Imaging and Urinalysis of Immunotherapeutic Response in Renal Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
This study reported renal‐clearable bio‐orthogonal near‐infrared fluorogenic probes (BGRs) that specifically imaging and urinalysis of granzyme B for dynamic evaluation of RCC immunotherapy. BGRs not only differentiate immunotherapeutic responses in orthotopic RCC mice, but also enable sensitive optical urinalysis of granzyme B in clinical specimens ...
Xingyue Yang   +9 more
wiley   +1 more source

tBid‐Mediated Genetic Ablation of Connective Tissue Cells Reveals Their Key Regulatory Function During Limb Regeneration in Axolotls

open access: yesAdvanced Science, EarlyView.
We establish a tBid‐mediated cell ablation system in axolotls, achieve rapid and efficient ablation of multiple cell types, including muscle stem cell, spinal cord cell, and connective tissue (CT) cells. We investigate the role of CT using tBid‐mediated CT ablation and identify its essential role for limb development and regeneration.
Yan Hu   +11 more
wiley   +1 more source

Transcriptional silencing of uPAR and MMP-9 activates caspase-3, caspase-9 and PARP.

open access: yes, 2012
Activity of caspase-3 and caspase-9 in Daoy and D283 cells was determined using A) caspase-3 and B) caspase-9 colorimetric activity kits. Total cell lysates collected from transfected cells (with and with radiation) were collected, incubated with the ...
Christopher S. Gondi (138231)   +5 more
core   +1 more source

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