Results 311 to 320 of about 301,365 (321)
Sperm caspase-9 in oligoasthenoteratozoospermic men with and without varicocele [PDF]
Fertility and Sterility, 2011 To assess sperm caspase-9 activity in infertile oligoasthenoteratozoospermic (OAT) men with and without varicocele.Prospective.Academic setting.Eighty men: healthy fertile control subjects (n = 20), OAT (n = 25), and OAT associated with left-side varicocele (n = 35).History taking, clinical examination, semen analysis,assessment of seminal caspase-9 ...
Mohamed Ahmed Elbaz +5 more
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The effect of caspase-9 in the differentiation of SH-SY5Y cells
European Journal of Pharmacology, 2021Neuroblastoma is the most common solid malignant tumor in infants and young children. Its origin is the incompletely committed precursor cells from the autonomic nervous system. Neuroblastoma cells are multipotent cells with a high potency of differentiation into the neural cell types.
Zahra Madadi +4 more
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Caspase 9: context-dependent killer
Trends in Cell Biology, 1998Abstract KUIDA, K. et al . (1998) Reduced apoptosis and cytochrome c -mediated caspase activation in mice lacking caspase 9 Cell 94, 325–337 Hakem, R. et al .
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Activation of caspase 9 in a rat model of experimental glaucoma
Current Eye Research, 2002We investigated retinal ganglion cell (RGC) death and activation of caspase 9 in rats with experimental glaucoma.Elevated intraocular pressure (IOP) was induced in rats using the Morrison model. Surviving backlabeled RGC were counted and TUNEL staining detected apoptosis.
Ellen E. Freeman +4 more
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Analysis of Apaf-1 and Caspase 9 in Tumorigenesis [PDF]
, 2002 Abstract : The replicative exhaustion of Human diploid fibroblasts (HDFs) in culture is associated with an "irreversible" cell-cycle arrest known as replicative senescence. However, young cells can enter a similar phenotype to replicative senescence in response to expression of certain mitogenic oncogenes, oxidative stress, and DNA damage.
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Cytochrome C and Caspase-9 Expression in Huntington 's Disease
NeuroMolecular Medicine, 2002There is increasing evidence implicating apoptosis-mediated cell death in the pathogenesis of neurodegenerative diseases. One important event in the apoptotic cascade is the release of cytochrome c by mitochondria into the cytoplasm, activating caspase-9, leading to the subsequent activation of downstream executioner caspases.
Steven M. Hersch +12 more
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Regulation of Cell Death Protease Caspase-9 by Phosphorylation
Science, 1998Caspases are intracellular proteases that function as initiators and effectors of apoptosis. The kinase Akt and p21-Ras, an Akt activator, induced phosphorylation of pro–caspase-9 (pro-Casp9) in cells. Cytochrome c–induced proteolytic processing of pro-Casp9 was defective in cytosolic extracts from cells expressing either active Ras or Akt.
Henning R. Stennicke +7 more
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The Regulation of the Alternative Splicing of Caspase 9
2010VCU Theses and ...
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Apoptosis, 1999
Overcoming apoptosis resistance to chemotherapy and radiation may lead to a reduction in gastric cancer death. We hypothesize that the apoptotic machinery in gastric cancer cells is dependent upon specific cellular conditions. In the course of our study of the expression of apoptosis-related genes in human gastric cancer cell lines, we have identified ...
Kazuki Teramachi +4 more
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Overcoming apoptosis resistance to chemotherapy and radiation may lead to a reduction in gastric cancer death. We hypothesize that the apoptotic machinery in gastric cancer cells is dependent upon specific cellular conditions. In the course of our study of the expression of apoptosis-related genes in human gastric cancer cell lines, we have identified ...
Kazuki Teramachi +4 more
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