Results 281 to 290 of about 509,167 (309)

Stimuli‐Responsive Supramolecular Biomaterials for Cancer Theranostics

Advanced Science, EarlyView.
The ultimate goal of cancer theranostics is to get imaging agents and therapeutic cargo to tumor sites when and where they are required. “Smart” systems should be developed. This review discusses the characteristics of physiological stimuli, types and action modes of external stimuli, construction approaches and working principles, as well as ...
Wenting Hu, Binglin Ye, Guocan Yu, Feihe Huang, Zhengwei Mao   +4 more
wiley   +1 more source

The bone phenotype associated with cherubism is independent of Caspase-1-dependent inflammasome activation in the mouse. [PDF]

PLoS One
Rabhi BV, Thomasseau S, Decrouy X, Cohen-Solal M, Deckert M, Coudert AE, Brial F.   +6 more
europepmc   +1 more source

DNMT2‐m5C‐ACLY Axis Promotes Lenvatinib Resistance in Hepatocellular Carcinoma Through Histone Acetylation‐Mediated Notch Pathway

Advanced Science, EarlyView.
Lenvatinib resistance poses a major challenge in advanced hepatocellular carcinoma (HCC). This study reveals that DNMT2 upregulation is a key driver, which stabilizes ACLY mRNA via m5C modification and activates the Notch signaling pathway. Crucially, combining ACLY inhibitors with lenvatinib overcomes resistance and suppresses tumors, offering a ...
Shiguang Yang, Jie Li, Shengwei Mao, Xuhui Zhao, Douwaner Liu, Jiafeng Chen, Jialu Fu, Yichao Bu, Xiaoling Wu, Shaoqing Liu, Qifeng Yu, Qiongzhu Dong, Zheng Tang, Yuan Fang, Yinghong Shi   +14 more
wiley   +1 more source

Cordycepin attenuates NLRP3/Caspase-1/GSDMD-mediated LPS-induced macrophage pyroptosis. [PDF]

Front Pharmacol
Liu Z, Lv L, Wei J, Xie Y, Jili M, Huang Y, Yang R, Luo Y.   +7 more
europepmc   +1 more source

Increased serum caspase-1 in adult-onset Still's disease. [PDF]

PLoS One
Matsumoto H, Yoshida S, Koga T, Fujita Y, Sumichika Y, Saito K, Temmoku J, Asano T, Sato S, Mizokami M, Sugiyama M, Migita K.   +11 more
europepmc   +1 more source

A new type of Caspase-1 upon recognizing bacteria inhibits GSDME-dependent histone modification and NF-κB signaling. [PDF]

Commun Biol
Chang R, Sun J, Leng J, Wang Z, Mu S, Li Y, Wang J, Song L.   +7 more
europepmc   +1 more source

Caspase-1-licensed pyroptosis drives dsRNA-mediated necroptosis and dampens host defense against bacterial pneumonia. [PDF]

PLoS Pathog
Luo Q, Shen L, Yang S, Zhang Y, Pan Y, Wu Z, Shu Q, Chen Q.   +7 more
europepmc   +1 more source

Correction to "Adipose Tissue IL-18 Production Is Independent of Caspase-1 and Caspase-11". [PDF]

Immun Inflamm Dis
europepmc   +1 more source