Results 151 to 160 of about 530,883 (357)
Caspase-9 swings both ways in the apoptosome
Molecular & Cellular Oncology, 2017 For nearly 2 decades, investigators have debated whether cysteinyl-aspartate-specific protease 9 (caspase-9) is activated within the apoptotic protease-activating factor 1 (Apaf-1) apoptosome through proximity-induced homodimerization or through ...
Chu-Chiao Wu, Shawn B. Bratton
doaj +1 more source
Ceramide Formation Leads to Caspase-3 Activation during Hypoxic PC12 Cell Death [PDF]
, 1998 Shinichi Yoshimura +10 more
openalex +1 more source
Advanced Functional Materials, EarlyView.FeDSNP‐Pa, a metallized nanoparticle loaded with sodium pyruvate (Pa), exerts triple therapeutic effects by scavenging reactive oxygen species (ROS), suppressing inflammatory responses, and inhibiting pyroptosis signaling pathways. This multifunctional neuroprotective strategy protecting retinal ganglion cells (RGCs) from elevated intraocular pressure ...
Yukun Wu +5 more
wiley +1 more source
Hubungan Antara Ekspresi Ki-67 Dan Kaspase-3 Dengan Respons Kemoterapi Neoajuvan Pada Pasien Karsinoma Serviks Stadium IB2 Dan IIA2 Di Rumah Sakit Dr. Hasan Sadikin, Bandung [PDF]
, 2016 Cervical carcinoma is the second ranks cancer in women in developing countries. This study was a retrospective cohortstudy of the relationship between the role of Ki-67 expression and caspase-3 on tumor shrinkage response in cervical carcinoma stage IB2 ...
HARSONO, A. B. (ALI) +2 more
core
Drug Design, Development and Therapy, 2018 Hengwen Chen,* Yan Dong,* Xuanhui He, Jun Li, Jie Wang Guang’anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China *These authors contributed equally to this work Background: Paeoniflorin (PF) is the active component of ...
Chen H, Dong Y, He X, Li J, Wang J
doaj
Apoptotic Effect of Coix Polysaccharides on A549 Lung Cancer Cells in Vitro
Chinese Journal of Lung Cancer, 2012 Background and objective Coix seeds are commonly used in Traditional Chinese Medicine and ingested through daily diet. The aim of this study is to analyze the apoptotic effect of coix polysaccharides on A549 cells.
Cheng LUO, Wei LIU, Xiangyi LU
doaj +1 more source
Cross-Resistance of CD95- and Drug-Induced Apoptosis as a Consequence of Deficient Activation of Caspases (ICE/Ced-3 Proteases) [PDF]
, 1997 Marek Łoś +5 more
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Advanced Functional Materials, EarlyView.Zr‐Fe MOF@Ribociclib@Herceptin (ZFRH) efficiently targets/kills Human Epidermal Growth Factor Receptor 2/Estrogen Receptor‐positive (HER2/ER+) breast cancer cells. It combats tumors by: 1) Elevating ROS, altering redox balance; 2) Inhibiting transcription; 3) Inducing pyroptosis.
Hongkun Miao +8 more
wiley +1 more source
In Situ Immunodetection of Neuronal Caspase-3 Activation in Alzheimer Disease [PDF]
, 1999 Lee A. Selznick +6 more
openalex +1 more source
Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes
Advanced Functional Materials, EarlyView.Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth +2 more
wiley +1 more source