Results 261 to 270 of about 16,798,464 (375)
Gasdermin D (GSDMD) does not only reduce pancreatic enzyme synthesis but also induces pancreatic acinar cells to express mucin 1 (MUC1), which forms a barrier to prevent digestive enzyme‐mediated digestion. However, GSDMD can promote the secretion of inflammatory cytokines by macrophages and aggravate pancreatic histological injury by expanding ...
Chaoxu Liu+10 more
wiley +1 more source
Metamizole limits proliferation in chronic myeloid leukemia cells and triggers apoptosis via the bax/bcl-2/caspase-3 cascade. [PDF]
Maytalman E, Nemutlu Samur D.
europepmc +1 more source
Cisplatin causes reactive oxygen species accumulation, leading to apoptosis and inflammation in cochlear hair cells. Small extracellular vesicles primarily derived from the damaged hair cells likely contribute to cisplatin‐induced ototoxicity, carrying a variety of microRNAs and proteins.
Jingru Ai+14 more
wiley +1 more source
αB-crystallin enhances radioresistance in basal-like breast cancer cells by suppressing caspase-3 activation. [PDF]
Yuan Y, Zhang X, Xu Y, Ge Y, Wu A.
europepmc +1 more source
Mesoporous gold nanospheres confined platinum nanoclusters (MGNSs@Pt) is developed as robust hydroxyl radical and oxygen nanogenerators for multimodal therapies. Their NIR‐II LSPR property also allowed MGSNs to be ideal phototheranostic agents. The chemodynamic and photothermal therapy efficiently induced the tumor cell apoptosis, enabling the MGNSs@Pt
Fei Cun+7 more
wiley +1 more source
Caerin 1.1 and 1.9 peptides induce acute caspase 3/GSDME-mediated pyroptosis in epithelial cancer cells. [PDF]
Luo Y+13 more
europepmc +1 more source
EBBP expression is significantly upregulated in DOX‐treated cardiomyocytes. Mechanistically, EBBP interacts with GRP78 to mediate K63‐linked ubiquitination, thereby attenuating the inhibitory GRP78‐PERK interaction and triggering activation of the PERK‐mediated integrated stress response (ISR).
Zilong Chen+9 more
wiley +1 more source
Role of RGS17 in cisplatin-induced cochlear inflammation and ototoxicity via caspase-3 activation. [PDF]
Al Aameri RFH+6 more
europepmc +1 more source
The presence and subcellular localization of caspase 3‐like proteinases in plant cells [PDF]
Henrie A. A. J. Korthout+4 more
openalex +1 more source
The proposed working model for how adipocytes participate in cisplatin resistance in osteosarcoma. The adipocytes secret A1BG and stabilize NAMPT, leading to increased NAD⁺ levels and subsequent increased PARP1‐mediated DNA repair, resulting in cisplatin resistance in osteosarcoma finally.
Yonghui Liang+8 more
wiley +1 more source