Results 71 to 80 of about 16,798,464 (375)
During low tide intertidal organisms face severe temperature fluctuations. This situation may be more pronounced in the context of climate change.
Fengshen Zhao, Heding Shen
doaj
A Novel Combination Therapy Approach Targeting STAT3 and Autophagy in Glioblastoma
The aggressive brain cancer glioblastoma (GBM) is notoriously resistant to radiotherapy and chemotherapy, which drives tumor recurrence and relapse. GBM cells are highly addicted to STAT3 (signal transducer and activator of transcription 3) and STAT3 ...
Sujoy Bhattacharya+2 more
doaj +1 more source
Caspase-3 and caspase-6 in ductal breast carcinoma: a descriptive study.
Caspases are the main point in the apoptotic process. We have collected some information from 210 cases of Ductal breast cancer (pT1 - pT2) such as tumour size, histological differentiation degree, lymph node status and tumor necrosis in the infiltrating component and we have evaluated the number of apoptotic cells or bodies by TUNEL technique as well ...
Blázquez, S.+6 more
openaire +3 more sources
Delivery of mixed-lineage kinase domain-like protein by vapor nanobubble photoporation induces necroptotic-like cell death in tumor cells [PDF]
Modern molecular medicine demands techniques to efficiently deliver molecules directly into mammalian cells. As proteins are the final mediators of most cellular pathways, efficient intracellular protein delivery techniques are highly desired.
Braeckmans, Kevin+10 more
core +2 more sources
Irisin Protects Against Hind Limb Ischemia Reperfusion Injury
Ayşegül Küçük,1,* Yücel Polat,2 Aydan Kılıçarslan,3 Nuran Süngü,3 Hakan Kartal,4 Ali Doğan Dursun,5,* Mustafa Arslan6 1Kutahya Health Sciences University, Medical Faculty, Department of Physiology, Kutahya ...
Küçük A+6 more
doaj
Impact of Aluminium phthalocyanine nanoconjugate on melanoma stem cells
Metastatic melanoma cancer stem cells are subpopulations linked to tumour development, immunoevasive behaviour, treatment resistance, and metastasis, all of which contribute to a poor prognosis.
Bridgette Mkhobongo+2 more
doaj +1 more source
Salmonella Pathogenesis and Processing of Secreted Effectors by Caspase-3 [PDF]
The enteric pathogen Salmonella enterica serovar Typhimurium causes food poisoning resulting in gastroenteritis. The S. Typhimurium effector Salmonella invasion protein A (SipA) promotes gastroenteritis by functional motifs that trigger either mechanisms
A. Maldonado-Contreras+28 more
core +1 more source
Cytotoxic chemotherapy, still the most widely adopted anticancer treatment, aims at eliminating cancer cells inducing apoptosis with DNA damaging agents, exploiting the differential replication rate of cancer vs.
Emanuele Bruni+5 more
doaj +1 more source
Effect of sikkam (Bischofia javanica Blume) ethanolic extract on the quality and quantity of hyperglycemic rat sperm [PDF]
Context: Hyperglycemia causes diabetes mellitus (DM), abnormal metabolism, oxidative stress, and chronic complications such as impotence. Hyperglycemia causes testicular atrophy and stromal cell, seminiferous tubular damage, and spermatogenic cells ...
Syafruddin Ilyas+3 more
doaj
Protection by 20-5,14-HEDGE Against Surgically-Induced Ischemia Reperfusion Lung Injury in Rats [PDF]
Background We previously reported that the cytochrome P450 product 20-hydroxyeicosatetraenoic acid has prosurvival effects in pulmonary artery endothelial cells and ex vivo pulmonary arteries.
Ali, Irshad+6 more
core +2 more sources