Results 71 to 80 of about 16,798,464 (375)

Analyses of the differential expression of cloned Caspase-3 and Caspae-9 genes, of Onchidium reevesii, exposed to extreme hot and cold conditions

open access: yesAquaculture and Fisheries, 2021
During low tide intertidal organisms face severe temperature fluctuations. This situation may be more pronounced in the context of climate change.
Fengshen Zhao, Heding Shen
doaj  

A Novel Combination Therapy Approach Targeting STAT3 and Autophagy in Glioblastoma

open access: yesAutophagy Reports, 2022
The aggressive brain cancer glioblastoma (GBM) is notoriously resistant to radiotherapy and chemotherapy, which drives tumor recurrence and relapse. GBM cells are highly addicted to STAT3 (signal transducer and activator of transcription 3) and STAT3 ...
Sujoy Bhattacharya   +2 more
doaj   +1 more source

Caspase-3 and caspase-6 in ductal breast carcinoma: a descriptive study.

open access: yesHistology and histopathology, 2006
Caspases are the main point in the apoptotic process. We have collected some information from 210 cases of Ductal breast cancer (pT1 - pT2) such as tumour size, histological differentiation degree, lymph node status and tumor necrosis in the infiltrating component and we have evaluated the number of apoptotic cells or bodies by TUNEL technique as well ...
Blázquez, S.   +6 more
openaire   +3 more sources

Delivery of mixed-lineage kinase domain-like protein by vapor nanobubble photoporation induces necroptotic-like cell death in tumor cells [PDF]

open access: yes, 2019
Modern molecular medicine demands techniques to efficiently deliver molecules directly into mammalian cells. As proteins are the final mediators of most cellular pathways, efficient intracellular protein delivery techniques are highly desired.
Braeckmans, Kevin   +10 more
core   +2 more sources

Irisin Protects Against Hind Limb Ischemia Reperfusion Injury

open access: yesDrug Design, Development and Therapy, 2021
Ayşegül Küçük,1,* Yücel Polat,2 Aydan Kılıçarslan,3 Nuran Süngü,3 Hakan Kartal,4 Ali Doğan Dursun,5,* Mustafa Arslan6 1Kutahya Health Sciences University, Medical Faculty, Department of Physiology, Kutahya ...
Küçük A   +6 more
doaj  

Impact of Aluminium phthalocyanine nanoconjugate on melanoma stem cells

open access: yesArtificial Cells, Nanomedicine, and Biotechnology, 2023
Metastatic melanoma cancer stem cells are subpopulations linked to tumour development, immunoevasive behaviour, treatment resistance, and metastasis, all of which contribute to a poor prognosis.
Bridgette Mkhobongo   +2 more
doaj   +1 more source

Salmonella Pathogenesis and Processing of Secreted Effectors by Caspase-3 [PDF]

open access: yes, 2010
The enteric pathogen Salmonella enterica serovar Typhimurium causes food poisoning resulting in gastroenteritis. The S. Typhimurium effector Salmonella invasion protein A (SipA) promotes gastroenteritis by functional motifs that trigger either mechanisms
A. Maldonado-Contreras   +28 more
core   +1 more source

Lowering Etoposide Doses Shifts Cell Demise From Caspase-Dependent to Differentiation and Caspase-3-Independent Apoptosis via DNA Damage Response, Inducing AML Culture Extinction

open access: yesFrontiers in Pharmacology, 2018
Cytotoxic chemotherapy, still the most widely adopted anticancer treatment, aims at eliminating cancer cells inducing apoptosis with DNA damaging agents, exploiting the differential replication rate of cancer vs.
Emanuele Bruni   +5 more
doaj   +1 more source

Effect of sikkam (Bischofia javanica Blume) ethanolic extract on the quality and quantity of hyperglycemic rat sperm [PDF]

open access: yesJournal of Pharmacy & Pharmacognosy Research, 2022
Context: Hyperglycemia causes diabetes mellitus (DM), abnormal metabolism, oxidative stress, and chronic complications such as impotence. Hyperglycemia causes testicular atrophy and stromal cell, seminiferous tubular damage, and spermatogenic cells ...
Syafruddin Ilyas   +3 more
doaj  

Protection by 20-5,14-HEDGE Against Surgically-Induced Ischemia Reperfusion Lung Injury in Rats [PDF]

open access: yes, 2012
Background We previously reported that the cytochrome P450 product 20-hydroxyeicosatetraenoic acid has prosurvival effects in pulmonary artery endothelial cells and ex vivo pulmonary arteries.
Ali, Irshad   +6 more
core   +2 more sources

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