Results 91 to 100 of about 6,274,764 (195)

Caspase-3 activation in CSC treated U937 cells.

open access: yes, 2016
a) Treatment with CSC was associated with a time-dependent increase in caspase-3 activity. The increase in caspase-3 activity, compared to vehicle-treated cells, was found to be significant 24H and 48H after CSC treatment.
PSS Rao (2802544)   +4 more
core   +1 more source

Plasmalogens inhibit cleavage of caspase-9 and caspase-3.

open access: yes, 2013
A) Serum starvation increases cleavage of caspase-9 but not of caspase-8 and caspase-12. Neuro-2A cells were cultured in the culture medium supplemented with 10% FBS (control group), 0% FBS (serum starvation) and 0% FBS plus Pls of 5 and 20 µg/ml for 72 ...
Toshihiko Katafuchi (259003)   +5 more
core   +1 more source

Beta-mangostin from activates the intrinsic apoptosis pathway through reactive oxygen species with downregulation of the HSP70 gene in the HL60 cells associated with a G/G cell-cycle arrest

open access: yesTumor Biology, 2017
Xanthones are phytochemical compounds found in a number of fruits and vegetables. Characteristically, they are noted to be made of diverse properties based on their biological, biochemical, and pharmacological actions.
Fatima Abdelmutaal Ahmed Omer   +7 more
doaj   +1 more source

SfDredd cleaved Sf-caspase-1 when transfected in Sf9 cells.

open access: yes, 2016
Plasmids expressing FLAG-tagged SfDredd and HA-tagged Sf-caspase-1 were co-transfected into Sf9 cells. Mock treated cells, GFP expressed Sf9 cells, and, GFP and Sf-caspase-1 co-expressed Sf9 cells were used as controls.
Andong Wu (201754)   +5 more
core   +1 more source

Caspase-10 Negatively Regulates Caspase-8-Mediated Cell Death, Switching the Response to CD95L in Favor of NF-κB Activation and Cell Survival.

open access: yes, 2017
Formation of the death-inducing signaling complex (DISC) initiates extrinsic apoptosis. Caspase-8 and its regulator cFLIP control death signaling by binding to death-receptor-bound FADD.
M Ploesser (7788878)   +9 more
core   +4 more sources

SfDredd directly cleaved Sf-caspase-1 in vitro.

open access: yes, 2016
(A) Sf-caspase-1-C178A (300 nmol/L) was incubated with 300 nmol/L of C-terminally His-tagged SfDredd, SfDredd-C443A or SfDronc at 37°C for 1 h in Na-Citrate buffer and then subjected to immunoblotting using an antibody against Sf-caspase-1.
Andong Wu (201754)   +5 more
core   +1 more source

Paeoniflorin improves cardiac function and decreases adverse postinfarction left ventricular remodeling in a rat model of acute myocardial infarction

open access: yesDrug Design, Development and Therapy, 2018
Hengwen Chen,* Yan Dong,* Xuanhui He, Jun Li, Jie Wang Guang’anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China *These authors contributed equally to this work Background: Paeoniflorin (PF) is the active component of ...
Chen H, Dong Y, He X, Li J, Wang J
doaj  

HSP47 expression affected mitochondria caspase-9 cleavage.

open access: yes, 2013
(A) NIH3T3 cells treated with GalNAc-bn for the indicated periods were examined by western blot analysis using an antibody against caspase-9. NIH3T3 cells treated with staurosporine (STS) were used as a positive control for caspase-9 cleavage induction ...
Tatsunori Mizuno (439242)   +4 more
core   +1 more source

Nitric oxide and thioredoxin modulate the activity of caspase 9 in HepG2 cells. [PDF]

open access: yesBiochim Biophys Acta Gen Subj, 2023
Chakraborty S   +6 more
europepmc   +1 more source

Interactions in the Active Site Loops are Important for Maintaining the Active Site Environment of (Pro)caspase-3

open access: yes, 2004
Apoptosis is obligatory to development and in maintaining the vital balance between cell growth and death. Commitment to apoptosis involves a proteolytic cascade by a family of cysteine proteases named caspases.
Feeney, Brett
core  

Home - About - Disclaimer - Privacy