Results 81 to 90 of about 6,274,764 (195)
Inhibition of caspase-8 and caspase-9 suppressed the protein level of the cleaved caspase-3.
, 2016 Western Blot results after inhibiting either caspase-8 or caspase-9 or both of them. (i, ii) Representative protein bands of Western Blot experiments. (a, b) Mean expression levels of the proteins normalized to GAPDH, from three independent experiments ...
Chun Xu (286394) +4 more
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Role of Serine 310 in the Activity and Temperature Profile of Human Caspase-9
مجله علمی دانشگاه علوم پزشکی کردستان, 2023 Background and Aim: Caspase-9 is a key enzyme in the intrinsic pathway of apoptosis that its activity is regulated by various mechanisms such as phosphorylation.
Raheleh Shakeri +3 more
doaj
Journal of Lipid Research, 2006 Two splice variants are derived from the caspase-9 gene, proapoptotic caspase-9a and antiapoptotic caspase-9b, by either the inclusion or exclusion of an exon 3, 4, 5, and 6 cassette.
Autumn Massiello, Charles E. Chalfant
doaj +1 more source
Drug Design, Development and Therapy, 2020 Chen H, Dong Y, He X, Li J, Wang J. Drug Des Devel Ther. 2018;12:823–836. The authors have advised Figure 11D on page 833 is incorrect. Due to an error at the time of figure assembly Figure 10D and Figure 11D were duplicated.
Chen H, Dong Y, He X, Li J, Wang J
doaj
Journal of Experimental & Clinical Cancer Research, 2018 Background Epstein-Barr virus (EBV) is widely found in nasopharyngeal carcinoma (NPC) tissue and associated with poor prognosis of patients. EBV nuclear antigen 1 (EBNA1) is expressed in all NPC tumors and plays multiple biological roles in both virus ...
Heng Zhou +7 more
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HCV-induced caspase-8 activity modulates caspase-9 cleavage.
, 2014 Huh7.5.1 cells were infected with HCVcc in the absence or presence of caspase-8 inhibitor (20 µM) for 72 h before harvest. The expression levels of truncated Bid (t-Bid) and cleaved caspase-9 were analyzed by Western blotting with antibodies specific to ...
Eui Ju Park (578043) +12 more
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CS increased pro-caspase and caspase 9 levels in macrophages.
, 2013 THP-1 macrophages were exposed to CS at concentrations of 1, 5 and 10 μg/ml for 24 h, then the macrophages were infected with Mtb. Relative units of pro-caspase 9 (A) and caspase 9 (B) are shown; band densities in the Western Blots were normalized ...
Leslie Chávez-Galán (489001) +4 more
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TUCAN/CARDINAL/CARD8 and apoptosis resistance in non-small cell lung cancer cells
BMC Cancer, 2006 Background Activation of caspase-9 in response to treatment with cytotoxic drugs is inhibited in NSCLC cells, which may contribute to the clinical resistance to chemotherapy shown in this type of tumor. The aim of the present study was to investigate the
Ferreira Carlos G +5 more
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Potency of moderate-intensity exercise on caspase-8 and caspase-9 expression in a DMBA-induced oral epithelial dysplasia rat model [PDF]
Journal of Applied Oral ScienceBackground Oral squamous cell carcinoma (OSCC) accounts for approximately 90% of oral cancers, with tobacco exposure representing one of its major risk factors.
Anis Irmawati +8 more
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Caspase-independent role of Apaf1 in T cell activation.
, 2018 LN cells from immunized Apaf1f/f-OTII or Lck-Cre-Apaf1f/f -OTII mice were stimulated with indicated doses of OVA or anti-CD3ε antibody in the presence or absence of z-VAD-fmk (z-VAD) for 48 hours.
Yasunobu Miyake (522605) +5 more
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